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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal alcohol consumption
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Accession:MP:0001425 term browser browse the term
Definition:aberrant behavioral-related or physiological-related intake of alcohol into the body
Synonyms:exact_synonym: abnormal ethanol consumption



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alcohol aversion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IMP RGD PMID:11535626 RGD:15036815 NCBI chr12:40,610,244...40,643,220 JBrowse link
alcohol preference term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IAGP DNA:polymorphism RGD PMID:11825850 RGD:2306323 NCBI chr 1:227,426,939...227,579,497 JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IAGP DNA:polymorphism RGD PMID:15900217 RGD:2306341 NCBI chr12:40,610,244...40,643,220 JBrowse link
G Arrb2 arrestin, beta 2 IAGP RGD PMID:18367649 RGD:401938607 NCBI chr10:55,645,539...55,653,485 JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IAGP DNA:polymorphism, missense mutation:promoter, cds RGD PMID:24611993 RGD:8662401 NCBI chr 4:85,553,163...85,596,203 JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 IAGP DNA:polymorphism:CDS:amino acid R100Q, Q allele higher in the alcohol preferring ANA line than the AA non-preferring line (P<0.0001) RGD PMID:14615016 RGD:1626511 NCBI chr10:27,311,965...27,327,337 JBrowse link
G Npy neuropeptide Y IAGP as compared to NP/Iusm; RGD PMID:27461754 RGD:11530013 NCBI chr 4:80,212,111...80,219,310 JBrowse link
G Npyem6Sage neuropeptide Y; zinc finger nuclease induced mutant 6, Sigma Advanced Genetic Engineering Labs IAGP as compared to NP/Iusm; RGD PMID:27461754 RGD:11530013
increased alcohol consumption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IAGP RGD PMID:16899727 RGD:1600586 NCBI chr 3:116,619,633...116,670,212 JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit IMP compared to wild type RGD PMID:31288250 RGD:150530288 NCBI chr 8:64,265,879...64,294,233 JBrowse link
G Chrna5em20(D398N)Pas cholinergic receptor, nicotinic, alpha 5 (neuronal); ZFN induced mutant 20,Pas IMP compared to wild type RGD PMID:31288250 RGD:150530288
G Crhr1 corticotropin releasing hormone receptor 1 IAGP DNA:polymorphism:promoter RGD PMID:17015825 RGD:1626233 NCBI chr10:89,540,192...89,583,466 JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12086672 RGD:1580677 NCBI chr 8:58,605,403...58,669,339 JBrowse link
G Npy neuropeptide Y IAGP as compared to NP/Iusm; RGD PMID:27461754 RGD:11530013 NCBI chr 4:80,212,111...80,219,310 JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:15670655 RGD:1642509 NCBI chr 2:170,200,027...170,210,286 JBrowse link
G Npyem6Sage neuropeptide Y; zinc finger nuclease induced mutant 6, Sigma Advanced Genetic Engineering Labs IAGP as compared to NP/Iusm; RGD PMID:27461754 RGD:11530013
low alcohol preference term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:30456835 RGD:13825259 NCBI chr 2:112,196,158...112,201,666 JBrowse link
G Ghsrem1Ottc growth hormone secretagogue receptor;CRISPR induced mutant 1, Ottc IMP RGD PMID:30456835 RGD:13825259

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5421
    behavior/neurological phenotype 614
      abnormal behavior 613
        abnormal behavioral response to xenobiotic 141
          abnormal alcohol consumption 106
            alcohol aversion 1
            alcohol preference 71
            decreased alcohol consumption 3
            increased alcohol consumption 33
            low alcohol preference 6
Path 2
Term Annotations click to browse term
  mammalian phenotype 5421
    behavior/neurological phenotype 614
      abnormal behavior 613
        abnormal consumption behavior 197
          abnormal drinking behavior 125
            abnormal alcohol consumption 106
              alcohol aversion 1
              alcohol preference 71
              decreased alcohol consumption 3
              increased alcohol consumption 33
              low alcohol preference 6
paths to the root