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ONTOLOGY REPORT - ANNOTATIONS


Term:decreased bone marrow cell number
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Accession:MP:0000333 term browser browse the term
Definition:decreased number of cells that make up the core cavities of bones when compared to the normal state
Synonyms:exact_synonym: bone marrow hypoplasia;   hypocellular bone marrow;   reduced bone marrow cell number
 alt_id: MP:0000174


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decreased bone marrow cell number term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 JBrowse link 17 46,303,220 46,328,031 RGD:5509061
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase JBrowse link 2 31,688,244 31,807,093 RGD:5509061
G Adar adenosine deaminase, RNA-specific JBrowse link 3 89,714,469 89,753,455 RGD:5509061
G Aldh2 aldehyde dehydrogenase 2, mitochondrial JBrowse link 5 121,566,027 121,593,824 RGD:5509061
G Arhgap1 Rho GTPase activating protein 1 JBrowse link 2 91,650,118 91,672,325 RGD:5509061
G Arid5b AT rich interactive domain 5B (MRF1-like) JBrowse link 10 68,092,523 68,279,355 RGD:5509061
G Asxl1 additional sex combs like 1 JBrowse link 2 153,345,830 153,404,007 RGD:5509061
G Atr ataxia telangiectasia and Rad3 related JBrowse link 9 95,857,597 95,953,217 RGD:5509061
G Bcl6 B cell leukemia/lymphoma 6 JBrowse link 16 23,965,050 23,988,866 RGD:5509061
G Bmi1 Bmi1 polycomb ring finger oncogene JBrowse link 2 18,677,018 18,686,629 RGD:5509061
G Braf Braf transforming gene JBrowse link 6 39,603,231 39,725,658 RGD:5509061
G Brca2 breast cancer 2, early onset JBrowse link 5 150,522,297 150,570,147 RGD:5509061
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit JBrowse link 8 84,338,631 84,640,251 RGD:5509061
G Ccna1 cyclin A1 JBrowse link 3 55,045,469 55,057,634 RGD:5509061
G Ccna2 cyclin A2 JBrowse link 3 36,564,865 36,573,038 RGD:5509061
G Ccnd3 cyclin D3 JBrowse link 17 47,505,051 47,599,689 RGD:5509061
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) JBrowse link 18 60,803,849 60,812,652 RGD:5509061
G Cd79a CD79A antigen (immunoglobulin-associated alpha) JBrowse link 7 24,897,497 24,901,858 RGD:5509061
G Chaf1b chromatin assembly factor 1, subunit B (p60) JBrowse link 16 93,883,900 93,906,115 RGD:5509061
G Commd10 COMM domain containing 10 JBrowse link 18 46,958,819 47,087,995 RGD:5509061
G Csf1 colony stimulating factor 1 (macrophage) JBrowse link 3 107,741,048 107,760,469 RGD:5509061
G Csf3r colony stimulating factor 3 receptor (granulocyte) JBrowse link 4 126,023,441 126,044,975 RGD:5509061
G Csnk1a1 casein kinase 1, alpha 1 JBrowse link 18 61,554,236 61,590,320 RGD:5509061
G Ctsk cathepsin K JBrowse link 3 95,499,210 95,509,387 RGD:5509061
G Cul4a cullin 4A JBrowse link 8 13,105,623 13,147,940 RGD:5509061
G Cxcl12 chemokine (C-X-C motif) ligand 12 JBrowse link 6 117,168,535 117,181,368 RGD:5509061
G Cxcr4 chemokine (C-X-C motif) receptor 4 JBrowse link 1 128,588,199 128,592,299 RGD:5509061
G Dhps deoxyhypusine synthase JBrowse link 8 85,071,486 85,075,162 RGD:5509061
G Dkc1 dyskeratosis congenita 1, dyskerin JBrowse link X 75,095,854 75,109,776 RGD:5509061
G Dot1l DOT1-like, histone H3 methyltransferase (S. cerevisiae) JBrowse link 10 80,755,101 80,795,461 RGD:5509061
G Dst dystonin JBrowse link 1 33,907,888 34,308,662 RGD:5509061
G E2f6 E2F transcription factor 6 JBrowse link 12 16,810,909 16,826,752 RGD:5509061
G Ebf1 early B cell factor 1 JBrowse link 11 44,618,100 45,008,096 RGD:5509061
G Elavl1 ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) JBrowse link 8 4,284,781 4,325,140 RGD:5509061
G Ep400 E1A binding protein p400 JBrowse link 5 110,664,373 110,770,927 RGD:5509061
G Epo erythropoietin JBrowse link 5 137,483,020 137,485,816 RGD:5509061
G Espl1 extra spindle pole bodies 1, separase JBrowse link 15 102,296,254 102,324,357 RGD:5509061
G Esrra estrogen related receptor, alpha JBrowse link 19 6,910,977 6,922,048 RGD:5509061
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit JBrowse link 11 101,191,115 101,226,463 RGD:5509061
G Fadd Fas (TNFRSF6)-associated via death domain JBrowse link 7 144,578,323 144,582,441 RGD:5509061
G Fancc Fanconi anemia, complementation group C JBrowse link 13 63,301,334 63,497,292 RGD:5509061
G Fancd2 Fanconi anemia, complementation group D2 JBrowse link 6 113,531,640 113,597,020 RGD:5509061
G Fbxw7 F-box and WD-40 domain protein 7 JBrowse link 3 84,814,990 84,979,198 RGD:5509061
G Fes feline sarcoma oncogene JBrowse link 7 80,377,758 80,387,954 RGD:5509061
G Flt3 FMS-like tyrosine kinase 3 JBrowse link 5 147,330,741 147,400,489 RGD:5509061
G Flt3l FMS-like tyrosine kinase 3 ligand JBrowse link 7 45,131,183 45,136,490 RGD:5509061
G Fubp1 far upstream element (FUSE) binding protein 1 JBrowse link 3 152,210,422 152,236,830 RGD:5509061
G Gab2 growth factor receptor bound protein 2-associated protein 2 JBrowse link 7 97,081,751 97,308,951 RGD:5509061
G Gata1 GATA binding protein 1 JBrowse link X 7,959,260 7,976,663 RGD:5509061
G Gja1 gap junction protein, alpha 1 JBrowse link 10 56,377,300 56,390,419 RGD:5509061
G Gmnn geminin JBrowse link 13 24,751,845 24,761,937 RGD:5509061
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano JBrowse link 6 113,067,428 113,077,244 RGD:5509061
G Hax1 HCLS1 associated X-1 JBrowse link 3 89,995,446 89,998,716 RGD:5509061
G Hck hemopoietic cell kinase JBrowse link 2 153,108,468 153,151,441 RGD:5509061
G Hdac1 histone deacetylase 1 JBrowse link 4 129,516,104 129,542,646 RGD:5509061
G Hdac2 histone deacetylase 2 JBrowse link 10 36,974,297 37,001,889 RGD:5509061
G Hip1 huntingtin interacting protein 1 JBrowse link 5 135,406,518 135,545,323 RGD:5509061
G Hoxa9 homeobox A9 JBrowse link 6 52,223,097 52,227,370 RGD:5509061
G Hoxb4 homeobox B4 JBrowse link 11 96,318,267 96,321,638 RGD:5509061
G Idh1 isocitrate dehydrogenase 1 (NADP+), soluble JBrowse link 1 65,158,616 65,186,479 RGD:5509061
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:5509061
G Igh immunoglobulin heavy chain complex JBrowse link 12 113,258,768 116,009,954 RGD:5509061
G Ikzf1 IKAROS family zinc finger 1 JBrowse link 11 11,684,962 11,772,930 RGD:5509061
G Il31ra interleukin 31 receptor A JBrowse link 13 112,521,931 112,580,732 RGD:5509061
G Il7 interleukin 7 JBrowse link 3 7,572,028 7,613,760 RGD:5509061
G Il7r interleukin 7 receptor JBrowse link 15 9,506,159 9,529,941 RGD:5509061
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 1 87,620,312 87,720,510 RGD:5509061
G Jak2 Janus kinase 2 JBrowse link 19 29,251,803 29,313,095 RGD:5509061
G Kat6a K(lysine) acetyltransferase 6A JBrowse link 8 22,859,442 22,943,259 RGD:5509061
G Kdm1a lysine (K)-specific demethylase 1A JBrowse link 4 136,550,533 136,602,787 RGD:5509061
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 5 75,574,987 75,656,722 RGD:5509061
G Kitl kit ligand JBrowse link 10 100,015,615 100,100,416 RGD:5509061
G Kmt2a lysine (K)-specific methyltransferase 2A JBrowse link 9 44,803,355 44,881,352 RGD:5509061
G Lepr leptin receptor JBrowse link 4 101,717,137 101,815,352 RGD:5509061
G Lig4 ligase IV, DNA, ATP-dependent JBrowse link 8 9,970,020 9,977,696 RGD:5509061
G Lmo2 LIM domain only 2 JBrowse link 2 103,957,903 103,981,878 RGD:5509061
G Lyz2 lysozyme 2 JBrowse link 10 117,277,541 117,282,272 RGD:5509061
G Mdm2 transformed mouse 3T3 cell double minute 2 JBrowse link 10 117,688,875 117,710,758 RGD:5509061
G Mdm4 transformed mouse 3T3 cell double minute 4 JBrowse link 1 132,986,105 133,030,587 RGD:5509061
G Msi2 musashi RNA-binding protein 2 JBrowse link 11 88,339,382 88,718,306 RGD:5509061
G Mybl2 myeloblastosis oncogene-like 2 JBrowse link 2 163,054,327 163,084,688 RGD:5509061
G Ndor1 NADPH dependent diflavin oxidoreductase 1 JBrowse link 2 25,244,813 25,255,509 RGD:5509061
G Nf1 neurofibromin 1 JBrowse link 11 79,339,590 79,581,609 RGD:5509061
G Nlk nemo like kinase JBrowse link 11 78,567,168 78,697,595 RGD:5509061
G Ociad1 OCIA domain containing 1 JBrowse link 5 73,292,769 73,314,077 RGD:5509061
G Pbx1 pre B cell leukemia homeobox 1 JBrowse link 1 168,119,364 168,432,365 RGD:5509061
G Pcid2 PCI domain containing 2 JBrowse link 8 13,075,476 13,105,343 RGD:5509061
G Pclaf PCNA clamp associated factor JBrowse link 9 65,890,323 65,903,551 RGD:5509061
G Pfdn1 prefoldin 1 JBrowse link 18 36,403,679 36,454,495 RGD:5509061
G Pgm3 phosphoglucomutase 3 JBrowse link 9 86,552,476 86,571,878 RGD:5509061
G Phf20 PHD finger protein 20 JBrowse link 2 156,196,647 156,309,953 RGD:5509061
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 7 90,130,192 90,209,447 RGD:5509061
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:5509061
G Prf1 perforin 1 (pore forming protein) JBrowse link 10 61,297,751 61,304,684 RGD:5509061
G Prkdc protein kinase, DNA activated, catalytic polypeptide JBrowse link 16 15,637,444 15,842,239 RGD:5509061
G Procr protein C receptor, endothelial JBrowse link 2 155,751,125 155,755,478 RGD:5509061
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:5509061
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 JBrowse link 2 90,910,713 90,918,050 RGD:5509061
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 5 121,130,533 121,191,397 RGD:5509061
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 67,665,501 67,724,632 RGD:5509061
G Racgap1 Rac GTPase-activating protein 1 JBrowse link 15 99,620,496 99,651,656 RGD:5509061
G Rad50 RAD50 double strand break repair protein JBrowse link 11 53,649,519 53,707,319 RGD:5509061
G Rag2 recombination activating gene 2 JBrowse link 2 101,624,712 101,632,528 RGD:5509061
G Rasa3 RAS p21 protein activator 3 JBrowse link 8 13,567,218 13,677,587 RGD:5509061
G Rassf2 Ras association (RalGDS/AF-6) domain family member 2 JBrowse link 2 131,992,850 132,030,416 RGD:5509061
G Rbm38 RNA binding motif protein 38 JBrowse link 2 173,021,891 173,034,734 RGD:5509061
G Rc3h1 RING CCCH (C3H) domains 1 JBrowse link 1 160,906,411 160,974,976 RGD:5509061
G Rel reticuloendotheliosis oncogene JBrowse link 11 23,736,847 23,770,969 RGD:5509061
G Rhbdf1 rhomboid 5 homolog 1 JBrowse link 11 32,209,585 32,222,331 RGD:5509061
G Rnf2 ring finger protein 2 JBrowse link 1 151,469,398 151,500,991 RGD:5509061
G Rnf8 ring finger protein 8 JBrowse link 17 29,614,789 29,641,664 RGD:5509061
G Rpl27a ribosomal protein L27A JBrowse link 7 109,519,195 109,522,369 RGD:5509061
G Rps27l ribosomal protein S27-like JBrowse link 9 66,944,624 66,949,522 RGD:5509061
G Runx1 runt related transcription factor 1 JBrowse link 16 92,601,466 92,826,074 RGD:5509061
G Ruvbl1 RuvB-like protein 1 JBrowse link 6 88,465,409 88,497,566 RGD:5509061
G Serpini2 serine (or cysteine) peptidase inhibitor, clade I, member 2 JBrowse link 3 75,242,357 75,270,078 RGD:5509061
G Sirt6 sirtuin 6 JBrowse link 10 81,621,786 81,627,792 RGD:5509061
G Slc37a4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 JBrowse link 9 44,396,857 44,402,968 RGD:5509061
G Smim3 small integral membrane protein 3 JBrowse link 18 60,474,191 60,518,949 RGD:5509061
G Socs1 suppressor of cytokine signaling 1 JBrowse link 16 10,783,808 10,785,536 RGD:5509061
G Sod1 superoxide dismutase 1, soluble JBrowse link 16 90,220,762 90,226,333 RGD:5509061
G Sod2 superoxide dismutase 2, mitochondrial JBrowse link 17 13,007,839 13,018,119 RGD:5509061
G Sox17 SRY (sex determining region Y)-box 17 JBrowse link 1 4,490,928 4,497,426 RGD:5509061
G Sphk1 sphingosine kinase 1 JBrowse link 11 116,530,836 116,536,675 RGD:5509061
G Sphk2 sphingosine kinase 2 JBrowse link 7 45,709,463 45,718,002 RGD:5509061
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 JBrowse link 12 87,305,058 87,388,355 RGD:5509061
G Src Rous sarcoma oncogene JBrowse link 2 157,423,906 157,471,838 RGD:5509061
G Srrt serrate RNA effector molecule homolog (Arabidopsis) JBrowse link 5 137,295,704 137,307,716 RGD:5509061
G Stk11 serine/threonine kinase 11 JBrowse link 10 80,115,767 80,130,679 RGD:5509061
G Syk spleen tyrosine kinase JBrowse link 13 52,582,610 52,648,792 RGD:5509061
G Tal1 T cell acute lymphocytic leukemia 1 JBrowse link 4 115,056,426 115,071,755 RGD:5509061
G Thoc5 THO complex 5 JBrowse link 11 4,895,283 4,928,867 RGD:5509061
G Timp1 tissue inhibitor of metalloproteinase 1 JBrowse link X 20,870,166 20,874,737 RGD:5509061
G Tle4 transducin-like enhancer of split 4 JBrowse link 19 14,448,072 14,598,183 RGD:5509061
G Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator JBrowse link 1 105,780,673 105,849,444 RGD:5509061
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 JBrowse link 14 78,277,446 78,308,043 RGD:5509061
G Trat1 T cell receptor associated transmembrane adaptor 1 JBrowse link 16 48,730,774 48,810,547 RGD:5509061
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:5509061
G Usp1 ubiquitin specific peptidase 1 JBrowse link 4 98,923,810 98,935,543 RGD:5509061
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 3 116,110,020 116,129,688 RGD:5509061
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 6 113,623,994 113,631,634 RGD:5509061
G Vpreb1 pre-B lymphocyte gene 1 JBrowse link 16 16,868,401 16,869,255 RGD:5509061
G Vpreb2 pre-B lymphocyte gene 2 JBrowse link 16 17,979,445 17,981,274 RGD:5509061
G Xist inactive X specific transcripts JBrowse link X 103,460,373 103,483,233 RGD:5509061
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 17 84,183,924 84,187,947 RGD:5509061
absent bone marrow cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pot1b protection of telomeres 1B JBrowse link 17 55,651,190 55,712,647 RGD:5509061
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:5509061
G Rad50 RAD50 double strand break repair protein JBrowse link 11 53,649,519 53,707,319 RGD:5509061
G Runx2 runt related transcription factor 2 JBrowse link 17 44,495,987 44,814,797 RGD:5509061
G Terc telomerase RNA component JBrowse link 3 96,414,437 96,414,833 RGD:5509061
absent common myeloid progenitor cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 3 89,714,469 89,753,455 RGD:5509061
G Atf4 activating transcription factor 4 JBrowse link 15 80,255,184 80,257,545 RGD:5509061
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase JBrowse link 2 118,598,202 118,641,592 RGD:5509061
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha JBrowse link 7 35,119,293 35,121,928 RGD:5509061
G Fancc Fanconi anemia, complementation group C JBrowse link 13 63,301,334 63,497,292 RGD:5509061
G Hip1 huntingtin interacting protein 1 JBrowse link 5 135,406,518 135,545,323 RGD:5509061
G Jak2 Janus kinase 2 JBrowse link 19 29,251,803 29,313,095 RGD:5509061
G Kat6a K(lysine) acetyltransferase 6A JBrowse link 8 22,859,442 22,943,259 RGD:5509061
G Ly6a lymphocyte antigen 6 complex, locus A JBrowse link 15 74,994,877 74,998,031 RGD:5509061
G Meis1 Meis homeobox 1 JBrowse link 11 18,880,428 19,019,651 RGD:5509061
G Pbx1 pre B cell leukemia homeobox 1 JBrowse link 1 168,119,364 168,432,365 RGD:5509061
G Spi1 spleen focus forming virus (SFFV) proviral integration oncogene JBrowse link 2 91,082,368 91,115,759 RGD:5509061
G Tal1 T cell acute lymphocytic leukemia 1 JBrowse link 4 115,056,426 115,071,755 RGD:5509061

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  mammalian phenotype 13563
    hematopoietic system phenotype 3730
      abnormal hematopoietic system morphology/development 3283
        abnormal bone marrow cell morphology/development 605
          abnormal bone marrow cell number 214
            decreased bone marrow cell number 154
              absent bone marrow cell + 18
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.