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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal myocardial fiber morphology
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Accession:MP:0000278 term browser browse the term
Definition:any structural anomaly of the terminally differentiated, non-proliferative, cardiac muscle fibers, the multinucleated muscle cells of the heart
Synonyms:exact_synonym: abnormal adult cardiomyocyte morphology;   abnormal cardiac muscle cell morphology;   abnormal myocardial cell morphology;   abnormal myocardial fibers;   abnormal myocardial fibre morphology;   myocardial fibers abnormalities
 narrow_synonym: myocardial fiber dysplasia;   myocardial fibre dysplasia
 broad_synonym: abnormal myocardial fibres;   myocardial fibres abnormalities
 alt_id: MP:0002994



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decreased myocardial fiber size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb16 zinc finger and BTB domain containing 16 IMP compared to wild type SHR/OlaIpcv; RGD PMID:28396530 RGD:150340623 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zbtb16em1Ipcv zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv IMP compared to wild type SHR/OlaIpcv; RGD PMID:28396530 RGD:150340623
increased myocardial fiber size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:144,076,911...144,122,714
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    muscle phenotype 199
      abnormal muscle morphology 98
        abnormal muscle fiber morphology 15
          abnormal myocardial fiber morphology 7
            abnormal intercalated disk morphology + 0
            abnormal myocardial fiber mitochondrial morphology + 0
            absent cardiac desmosomes 0
            decreased myocardial fiber number 0
            decreased myocardial fiber size 3
            increased myocardial fiber number 0
            increased myocardial fiber size 4
            myocardial fiber degeneration 0
            myocardial fiber disarray 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    cardiovascular system phenotype 1371
      abnormal cardiovascular system morphology 427
        abnormal heart morphology 331
          abnormal heart layer morphology 8
            abnormal myocardium layer morphology 8
              abnormal myocardial fiber morphology 7
                abnormal intercalated disk morphology + 0
                abnormal myocardial fiber mitochondrial morphology + 0
                absent cardiac desmosomes 0
                decreased myocardial fiber number 0
                decreased myocardial fiber size 3
                increased myocardial fiber number 0
                increased myocardial fiber size 4
                myocardial fiber degeneration 0
                myocardial fiber disarray 0
paths to the root