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MEASUREMENT METHODS - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:automated serum aspartate aminotransferase activity assay
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Accession:MMO:0000789 term browser browse the term
Definition:This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of serum, i.e. blood plasma from which clotting factors have been removed. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Blood AST level is used as an enzymatic marker for liver disease or damage.
Synonyms:exact_synonym: automated serum AST activity assay;   automated serum GOT activity assay;   automated serum aspartate transaminase activity assay;   automated serum glutamic-oxaloacetic transaminase activity assay


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Related Phenotype Data for Term "automated serum aspartate aminotransferase activity assay" (MMO:0000789)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Term paths to the root
Path 1
Term Annotations click to browse term
  measurement method 2368
    ex vivo method 1236
      enzyme or transport activity assay 3
        blood enzyme activity assay 3
          blood aspartate aminotransferase activity assay 0
            serum aspartate aminotransferase activity assay 0
              automated serum aspartate aminotransferase activity assay 0
Path 2
Term Annotations click to browse term
  measurement method 2368
    ex vivo method 1236
      ex vivo biological fluid analysis 305
        ex vivo blood analysis 250
          blood protein analysis 11
            blood enzyme activity assay 3
              blood aspartate aminotransferase activity assay 0
                serum aspartate aminotransferase activity assay 0
                  automated serum aspartate aminotransferase activity assay 0
paths to the root