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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Mechanic's hands
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Accession:HP:6001013 term browser browse the term
Definition:Mechanic's hands are fissured, erythematous, hyperkeratotic eruptions on the hands, resembling the type of occupational dermatosis said to resemble the hands of a manual laborer. The lesions are classically on the lateral edges of the fingers and thumbs, largely sparing the palmar, and dorsal aspects of the digits.
Comment:This feature can be observed in antisynthetase syndrome (ASyS), an autoimmune disease clinically manifested most often by interstitial lung disease, myositis, and arthritis.


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Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the integument 0
        Abnormality of the skin 0
          Abnormal skin morphology 0
            Regional abnormality of skin 0
              Abnormal skin morphology of the palm 0
                Palmar hyperkeratosis 0
                  Mechanic's hands 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the integument 0
        Abnormality of the skin 0
          Abnormal skin morphology 0
            Thickened skin 0
              Epidermal thickening 0
                Hyperkeratosis 0
                  Palmar hyperkeratosis 0
                    Mechanic's hands 0
paths to the root