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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.

Term:Absent zona pellucida
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Accession:HP:6000328 term browser browse the term
Definition:Lack of the oocyte extracellular matrix region (zona pellucida). This feature can be observed following follicular aspiration (retrieval of eggs for fertility treatments).
Comment:During in vitro fertilization treatment, oocyte retrieval is performed after ovarian stimulation via vaginal puncture. Cumulus-oocyte complexes, which consist of cumulus cells surrounding the centrally located oocyte, are isolated from the individual's follicular fluid. This term refers to the finding of oocytes lacking zonae pellucidae.



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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormal cellular phenotype 0
        Abnormal cell morphology 0
          Abnormal oocyte morphology 0
            Abnormal zona pellucida morphology 0
              Absent zona pellucida 0
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