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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Fetal trigonocephaly
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Accession:HP:4000142 term browser browse the term
Definition:A fetal ultrasound finding defined by flattening of the occiput with pointing of the frontal bones and brachycephaly with an increased cephalic index. It is characterized by keel shaped deformity of forehead with midline ridge, bilateral fronto temporal constriction with compensatory biparietal expansion, supra orbital and lateral orbital retrusion and hypotelorism. This finding is said to resemble a strawberry.
Comment:Fetal trigonocephaly can be seen in trisomy 18 (or other chromosomal abnormalities) and monogenic syndromes, particularly also in craniosynostosis syndromes and some skeletal dysplasias.
Synonyms:exact_synonym: Foetal trigonocephaly;   Strawberry sign;   Strawberry skull;   Strawberry-shaped skull

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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of prenatal development or birth 0
        Fetal anomaly 0
          Abnormal fetal morphology 0
            Abnormal fetal skeletal morphology 0
              Fetal trigonocephaly 0
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