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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.

Term:Coprolalia
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Accession:HP:0430112 term browser browse the term
Definition:Coprolalia denotes the involuntary utterance of obscenities. Intent is an important classifier in coprolalic behaviors, and unfortunately it remains unclear how to objectively distinguish coprolalia from common swearing.
Comment:In Tourette syndrome (TS), the unintended expression of coprolalic behaviors is encountered in about one-fifth of patients. Typical coprolalic behaviors in TS are characterized by the utterance of single short obscenities (e.g., in English, so-called four-letter words) with a different pitch or tone from ongoing speech. There have been only a few reports of patients exhibiting coprolalia in other neurological conditions, such as neurodevelopmental disorders (e.g., Kleine-Levin and fragile X syndrome), neurodegenerative syndromes (e.g., FTD, Alzheimer's disease, and chorea-acanthocytosis), after focal brain lesions, in encephalitis lethargica, or as ictal phenomenon.



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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system physiology 0
          Abnormal central motor function 0
            Involuntary vocalization 0
              Coprolalia 0
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