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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Synostosis of joints
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Accession:HP:0100240 term browser browse the term
Definition:The abnormal fusion of neighboring bones across a joint.
Comment:Note that contracture refers to a reduction of joint mobility due to permanent shortening of the soft parts around a joint, muscles, tendons, ligaments, fasciae, or skin. Ankylosis and contracture can occur together or alone. Fibrous ankylosis refers to adhesions between the opposing surface of a joint. Cartilaginous ankylosis implies the fusion of two apposed cartilaginous surfaces. Bony ankylosis or synostosis refers to an osseous union between articulating surfaces.
Synonyms:exact_synonym: Bony ankylosis;   Fusion of joints
 xref: UMLS:C4022183

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Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the musculoskeletal system 0
        Abnormality of the skeletal system 0
          Abnormality of musculoskeletal physiology 0
            Abnormality of joint mobility 0
              Synostosis of joints 0
                Fusion of middle ear ossicles 0
                Synostosis involving bones of the lower limbs + 0
                Synostosis involving bones of the upper limbs + 0
                Synostosis involving digits + 0
                Synostosis of carpals/tarsals + 0
                Synostosis of metacarpals/metatarsals + 0
                Vertebral fusion + 0
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