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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Abnormal fetal long-bone echogenicity
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Accession:HP:0034072 term browser browse the term
Definition:Any deviation from the normal appearing echogenicity of the fetal bone. Echogenicity refers to the ability of tissue to reflect ultrasound waves back toward the transducer and produce an echo. Whenever there is an interface of structures with different echogenicities, a visible difference in contrast will be apparent on the screen. The higher the echogenicity of tissues, the brighter they appear on ultrasound imaging.
Comment:Hyperechoic structures are seen as brighter on the US image relative to surrounding structures due to higher reflectivity of the US beam. Isoechoic structures are seen as bright as surrounding structures on conventional US imaging due to similar reflectivity to the US beam. Hypoechoic structures are seen as darker relative to the surrounding structures on the US image due to the US beam being reflected to a lesser extent. Anechoic structures that lack internal reflectors fail to reflect the US beam to the transducer and are seen as homogeneously black on imaging.

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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of prenatal development or birth 0
        Fetal anomaly 0
          Abnormal fetal morphology 0
            Abnormal fetal skeletal morphology 0
              Abnormal fetal long-bone echogenicity 0
                Increased fetal long bone echogenicity 0
                Reduced fetal long bone echogenicity 0
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