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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Systemic autoinflammation
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Accession:HP:0033428 term browser browse the term
Definition:Dysregulation of the innate immune system characterized by systemic pathobiology, i.e., with symptoms that can affect the entire body.
Comment:The main cell types of the innate immune system are monocytes, macrophages, and neutrophils and organ damage is mediated by neutrophils and macrophages.

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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the immune system 0
        Abnormality of immune system physiology 0
          Abnormal inflammatory response 0
            Increased inflammatory response 0
              Systemic autoinflammation 0
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