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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Substantia nigra hypointensity on susceptibility-weighted imaging
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Accession:HP:0033048 term browser browse the term
Definition:Hypointence (dark) appearance of the substantia nigra inmagnetic resonance imaging using susceptibility weighted imaging (SWI).
Comment:Susceptibility-weighted imaging (SWI) is a relatively new magnetic resonance (MR) technique that exploits the magnetic susceptibility differences of various tissues, such as blood, iron and calcification, as a new source of contrast enhancement. Low SWI signal intensity may suggest deposition of paramagnetic material.
Synonyms:exact_synonym: Low signal intensity in the substantia nigra on susceptibility-weighted imaging (SWI)


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Substantia nigra hypointensity on susceptibility-weighted imaging term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GTPBP2 GTP binding protein 2 IAGP OMIM:617988 HPO NCBI chr 6:43,620,494...43,631,333
Ensembl chr 6:43,605,316...43,629,264 		JBrowse link
G SLC44A1 solute carrier family 44 member 1 IAGP OMIM:618868 HPO NCBI chr 9:105,244,651...105,438,504
Ensembl chr 9:105,244,622...105,439,171 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 15292
    Phenotypic abnormality 15290
      Abnormality of the nervous system 10551
        Abnormal nervous system morphology 4209
          Morphological central nervous system abnormality 4062
            Abnormality of brain morphology 3010
              Abnormal midbrain morphology 86
                Abnormal substantia nigra morphology 27
                  Substantia nigra hypointensity on susceptibility-weighted imaging 2
Path 2
Term Annotations click to browse term
  Human phenotype 15292
    Phenotypic abnormality 15290
      Abnormality of the nervous system 10551
        Abnormal nervous system morphology 4209
          Morphological central nervous system abnormality 4062
            Abnormality of brain morphology 3010
              Abnormal forebrain morphology 2130
                Abnormal cerebral morphology 2103
                  Abnormal cerebral subcortex morphology 1169
                    Abnormal basal ganglia morphology 209
                      Abnormal substantia nigra morphology 27
                        Substantia nigra hypointensity on susceptibility-weighted imaging 2
paths to the root