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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Placental mesenchymal dysplasia
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Accession:HP:0032165 term browser browse the term
Definition:Placental mesenchymal dysplasia is a rare anomaly characterized by placentomegaly, dilatation of chorionic vessels and hydropic stem villi with cistern-like formation. It is often clinically mistaken for a partial hydatidiform mole but there is no trophoblastic proliferation. P57 immunohistochemical expression is discordant, showing a normal positive expression in the cytotrophoblastic cells, and loss of expression in the stromal cells.
Comment:Placental mesenchymal dysplasia is an unusual abnormality of the stem villi of the placenta that may be mistaken for a hydatidiform mole, and in particular, partial mole, owing to the mixture of cysts and normal-appearing parenchyma.

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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of prenatal development or birth 0
        Abnormalities of placenta or umbilical cord 0
          Abnormal placenta morphology 0
            Placental mesenchymal dysplasia 0
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