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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.

Term:Myelokathexis
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Accession:HP:0031160 term browser browse the term
Definition:Impaired egress of mature neutrophils from bone marrow causing neutropenia.
Comment:The word myelo-kathexis is derived from the Greek words for marrow (myelo) retention (kathexis). Unlike other forms of severe neutropenia, myelokathexis is characterized by granulocytic hyperplasia in the bone marrow, which contains neutrophils with cytoplasmic vacuoles, nuclear hypersegmentation, and pyknotic nuclear lobes connected by thin filaments.



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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of blood and blood-forming tissues 0
        Abnormality of bone marrow cell morphology 0
          Abnormal granulocytopoietic cell morphology 0
            Myelokathexis 0
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