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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Interlobular septal thickening
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Accession:HP:0030879 term browser browse the term
Definition:Presence of thickening of the interlobular septa of the lungs as seen on a CT scan.
Comment:Interlobular septa are 10-20nm long structures at the border of the secondary pulmonary lobules and which are usually perpendicular to the pleura in the periphery of the lung. Interlobular septa are composed of connective tissue and contain pulmonary venules and lymphatics. Diseases that affect one of the components of the interlobular septa may lead to thickening of the septa, which makes the visible on computed tomography (CT) scans. Some of the diseases that may be associated with this phenotypic feature are pulmonary edema, pulmonary lymphangitis carcinomatosis, leukemic or lymphomic involvement of the lung, diffuse alveolar hemorrhage, Nieman-Pick disease, and pneumonia.
Synonyms:exact_synonym: Interlobular lines (pulmonary CT finding);   Peripheral lines (pulmonary CT finding);   Septal lines (pulmonary CT finding);   Septal thickening (pulmonary CT finding);   Short lines (pumonary CT finding)
 narrow_synonym: Interlobular septal thickening on pulmonary HRCT
 xref: UMLS:C4280727


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Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the respiratory system 0
        Abnormal respiratory system morphology 0
          Abnormal pulmonary thoracic imaging finding 0
            Pulmonary interstitial high-resolution computed tomography abnormality 0
              Pulmonary interstitial thickening 0
                Interlobular septal thickening 0
                  Irregular septal thickening on pulmonary HRCT 0
                  Nodular septal thickening on pulmonary HRCT 0
                  Smooth septal thickening on pulmonary HRCT 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the respiratory system 0
        Abnormal respiratory system morphology 0
          Abnormal lung morphology 0
            Abnormal pulmonary interstitial morphology 0
              Pulmonary interstitial high-resolution computed tomography abnormality 0
                Pulmonary interstitial thickening 0
                  Interlobular septal thickening 0
                    Irregular septal thickening on pulmonary HRCT 0
                    Nodular septal thickening on pulmonary HRCT 0
                    Smooth septal thickening on pulmonary HRCT 0
paths to the root