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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Abnormal platelet granule secretion
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Accession:HP:0030396 term browser browse the term
Definition:Platelets are replete with secretory granules, which are critical to normal platelet function. Among the three types of platelet secretory granules - alpha-granules, dense granules, and lysosomes - the alpha-granule is the most abundant. Granule contents must be released from their intracellular repository in order to achieve their physiologic function, and this term refers to a functional defect in granule secretion.
Synonyms:xref: UMLS:C4072929


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of blood and blood-forming tissues 0
        Abnormality of thrombocytes 0
          Abnormal platelet function 0
            Abnormal platelet granule secretion 0
              Abnormal platelet alpha granule secretion 0
              Abnormal platelet dense granule secretion + 0
              Abnormal platelet lysosome secretion 0
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