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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

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Accession:HP:0025406 term browser browse the term
Definition:A state characterized by a feeling of weakness and loss of strength leading to a generalized weakness of the body.
Comment:Asthenia is to be distinguished from fatigue, because asthenia refers to a sensation of exhaustion which occurs before any effort. Asthenia is to be distinguished from myasthenia, which means a specific weakness of one or more muscles. Asthenia and fatigue can coexist.
Synonyms:exact_synonym: Lack of energy and strength;   Weakness
 related_synonym: Prostration

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  Human phenotype 0
    Phenotypic abnormality 0
      Constitutional symptom 0
        Asthenia 0
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