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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Increased bone mineral density
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Accession:HP:0011001 term browser browse the term
Definition:An abnormal increase of bone mineral density, that is, of the amount of matter per cubic centimeter of bones which is often referred to as osteosclerosis. Osteosclerosis can be detected on radiological examination as an increased whiteness (density) of affected bones.
Comment:This term may be merged with Increased bone density in the future or made obsolete.
Synonyms:exact_synonym: Increased bone density;   Osteosclerosis;   Osteosclerosis of bones
 alt_id: HP:0002796;   HP:0004350;   HP:0005711;   HP:0005741;   HP:0010738
 xref: MESH:D010026;   SNOMEDCT_US:49347007;   UMLS:C0029464

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Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the musculoskeletal system 0
        Abnormality of the skeletal system 0
          Abnormal skeletal morphology 0
            Abnormal bone structure 0
              Abnormal bone ossification 0
                Abnormality of bone mineral density 0
                  Increased bone mineral density 0
                    Bone-in-a-bone appearance of carpal bones 0
                    Clavicular sclerosis 0
                    Cortical sclerosis 0
                    Craniofacial osteosclerosis + 0
                    Generalized osteosclerosis 0
                    Increased bone density with cystic changes 0
                    Increased density of long bones + 0
                    Increased skull ossification + 0
                    Ivory epiphyses of the metacarpals + 0
                    Metacarpal diaphyseal endosteal sclerosis 0
                    Osteopetrosis 0
                    Osteopoikilosis 0
                    Patchy osteosclerosis + 0
                    Sclerosis of foot bone + 0
                    Sclerosis of hand bone + 0
                    Sclerosis of skull base + 0
                    Sclerotic scapulae 0
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