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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Abnormal corpus striatum morphology
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Accession:HP:0010994 term browser browse the term
Definition:Abnormality of the striatum, which is the largest nucleus of the basal ganglia, comprising the caudate, putamen and ventral striatum, including the nucleus accumbens.
Comment:The striatum (also known as the neostriatum or striate nucleus) contains the caudate nucleus and putamen, which are separated from one another by a white matter tract called the internal capsule. The striatum is part of the basal ganglia and receives input from the cerebral cortex. Essentially all cortical areas (sensory, motor and associational) project to the striatum. The other major input to the striatum comes from the thalamus, particularly the intralaminar thalamic nuclei.
Synonyms:exact_synonym: Abnormality of the neostriatum;   Abnormality of the striate nucleus;   Abnormality of the striatum
 xref: UMLS:C4023607


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system morphology 0
          Morphological central nervous system abnormality 0
            Abnormality of brain morphology 0
              Abnormal forebrain morphology 0
                Abnormal cerebral morphology 0
                  Abnormal cerebral subcortex morphology 0
                    Abnormal basal ganglia morphology 0
                      Abnormal corpus striatum morphology 0
                        Abnormal caudate nucleus morphology + 0
                        Abnormal putamen morphology + 0
                        Degeneration of the striatum 0
                        Striatal T2 hyperintensity 0
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