Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Avascular necrosis
go back to main search page
Accession:HP:0010885 term browser browse the term
Definition:A disease where there is cellular death (necrosis) of bone components due to interruption of the blood supply.
Comment:The interruption of the blood supply may have many different causes such as rapid growth, heredity causes, trauma or overuse, anatomic conformation, dietary imbalances or secondary effects of other diseases.
Synonyms:exact_synonym: Aseptic bone necrosis;   Aseptic necrosis;   Bone infarction;   Death of bone due to decreased blood supply;   Ischaemic bone necrosis;   Ischemic bone necrosis;   Osteochondronecrosis;   Osteonecrosis
 xref: MESH:D010020;   SNOMEDCT_US:240196003;   SNOMEDCT_US:398199007;   SNOMEDCT_US:72756009;   UMLS:C0029445;   UMLS:C0085660;   UMLS:C0520474;   UMLS:C0877326

show annotations for term's descendants           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the musculoskeletal system 0
        Abnormality of the skeletal system 0
          Abnormal musculoskeletal physiology 0
            Avascular necrosis 0
              Juvenile aseptic necrosis + 0
paths to the root