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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Delayed patellar ossification
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Accession:HP:0006454 term browser browse the term
Definition:Formation of bone in the patella later than normal.
Comment:The patella initially ossifies at between three and five years, commencing as multiple foci that rapidly coalesce. As the patellar ossification center enlarges the expanding margins may be irregular and associated with accessory ossification centers. These are most common superolaterally and may lead to the development of a bipartite patella. The bipartite patella has cartilaginous continuity despite the appearance of osseous discontinuity. The patella expands to all cartilaginous contours during late adolescence when the epiphyseal ossification centers around the knee are also in the final stages of maturation. The only cartilage not replaced is that occupying the superior two-thirds of the articular surface (the lower one-third is covered by the fat pad). The subchondral plate does not assume the actual articular contours until the late stages of osseous maturation (after ten to twelve years). Accordingly, typical measurements such as medial and lateral angulation cannot be accurately done prior to the final stages of patellar ossification expansion and maturation (PMID:6729496).
Synonyms:exact_synonym: Delayed patellae ossification
 related_synonym: Delayed bone maturation of the knee cap
 xref: UMLS:C4021597;   UMLS:C4280446


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Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of limbs 0
        Abnormality of the lower limb 0
          Abnormality of lower limb joint 0
            Abnormality of the knee 0
              Abnormal knee morphology 0
                Abnormal patella morphology 0
                  Delayed patellar ossification 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the musculoskeletal system 0
        Abnormality of the skeletal system 0
          Abnormal skeletal morphology 0
            Abnormal joint morphology 0
              Abnormality of lower limb joint 0
                Abnormality of the knee 0
                  Abnormal knee morphology 0
                    Abnormal patella morphology 0
                      Delayed patellar ossification 0
paths to the root