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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Prominent nasolabial fold
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Accession:HP:0005272 term browser browse the term
Definition:Exaggerated bulkiness of the crease or fold of skin running from the lateral margin of the nose, where nasal base meets the skin of the face, to a point just lateral to the corner of the mouth (cheilion, or commissure).
Synonyms:exact_synonym: Deep laugh lines;   Deep nasolabial crease;   Deep nasolabial fold;   Deep nasolabial groove;   Deep smile lines;   Nasolabial crease, prominent;   Prominent laugh lines;   Prominent nasolabial groove;   Prominent smile lines
 xref: UMLS:C1866487

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Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of head or neck 0
        Abnormality of the head 0
          Abnormality of the face 0
            Abnormality of the nose 0
              Abnormality of the nasolabial region 0
                Prominent nasolabial fold 0
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