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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Absence of lymph node germinal center
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Accession:HP:0002849 term browser browse the term
Definition:Absence of germinal centers in lymph nodes. Germinal centers are the parts of lymph nodes in which B lymphocytes proliferate, differentiate, mutate through somatic hypermutation and class switch during antibody responses.
Synonyms:exact_synonym: Absence of lymph node germinal centre;   Lymph nodes lack germinal center;   Lymph nodes lack germinal centre;   Lymphoid germinal center defect;   Lymphoid germinal centre defect
 xref: UMLS:C1847383


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Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the immune system 0
        Abnormality of the lymphatic system 0
          Abnormal lymph node morphology 0
            Absence of lymph node germinal center 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the cardiovascular system 0
        Abnormality of the vasculature 0
          Abnormality of the lymphatic system 0
            Abnormal lymph node morphology 0
              Absence of lymph node germinal center 0
paths to the root