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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Abnormal T cell morphology
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Accession:HP:0002843 term browser browse the term
Definition:Abnormal increase or decrease of total or subset T cell count. T cells are commonly characterized as CD3+ lymphocytes, or their subpopulations, in the blood, compared to a reference range for a given sex and age-group, measured ex vivo. These may include both TCR alpha/beta and gamma/delta T cells.
Comment:T-cells are lymphocytes whose principle function in the adaptive immune system is to mediate cell-mediated immunity.
Synonyms:exact_synonym: Abnormal T cells;   Abnormality of T cells;   Cellular immune defect;   Defective cellular immunity
 alt_id: HP:0002734;   HP:0030332
 xref: UMLS:C1855752


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Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of blood and blood-forming tissues 0
        Abnormal leukocyte morphology 0
          Abnormal lymphocyte morphology 0
            Abnormal T cell morphology 0
              Abnormal T cell count + 0
              Abnormal alpha-beta T cell morphology + 0
              Decreased CD4+ T cell ZAP-70 protein expression 0
              Decreased FOXP3-expressing T cell count 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the immune system 0
        Abnormal immune system morphology 0
          Abnormal cellular immune system morphology 0
            Abnormal leukocyte morphology 0
              Abnormal lymphocyte morphology 0
                Abnormal T cell morphology 0
                  Abnormal T cell count + 0
                  Abnormal alpha-beta T cell morphology + 0
                  Decreased CD4+ T cell ZAP-70 protein expression 0
                  Decreased FOXP3-expressing T cell count 0
paths to the root