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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.

Term:Osteolysis
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Accession:HP:0002797 term browser browse the term
Definition:Osteolysis refers to the destruction of bone through bone resorption with removal or loss of calcium.
Comment:Osteolysis may be a feature of neoplastic, infectious, metabolis, vascular, and joint disorders and is also a component of many hereditary diseases. Osteolysis may be highly localized or more diffuse. This term is meant to group the more specific osteolysis terms.
Synonyms:exact_synonym: Breakdown of bone;   Increased bone resorption;   Osteolytic defects of bones
 narrow_synonym: periprosthetic osteolysis
 alt_id: HP:0010737
 xref: EFO:0009761;   SNOMEDCT_US:203522001;   SNOMEDCT_US:30425001;   UMLS:C0221204



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Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the musculoskeletal system 0
        Abnormality of the skeletal system 0
          Abnormal skeletal morphology 0
            Abnormal bone structure 0
              Osteolysis 0
                Mandibular osteolysis 0
                Osteolysis involving bones of the lower limbs + 0
                Osteolysis involving bones of the upper limbs + 0
                Patchy reduction of bone mineral density 0
                Progressive clavicular acroosteolysis 0
                Rib osteolysis 0
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