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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Abnormal cerebral cortex morphology
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Accession:HP:0002538 term browser browse the term
Definition:Any structural abnormality of the cerebral cortex.
Comment:The cerebral cortex constitutes more than half the volume of the human brain and is presumed to be responsible for the neuronal computations underlying complex phenomena, such as perception, thought, language, attention, episodic memory and voluntary movement.
Synonyms:exact_synonym: Abnormality of the cerebral cortex
 xref: UMLS:C4025701

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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system morphology 0
          Morphological central nervous system abnormality 0
            Abnormal brain morphology 0
              Abnormal forebrain morphology 0
                Abnormal cerebral morphology 0
                  Abnormal cerebral cortex morphology 0
                    Abnormal cortical gyration + 0
                    Abnormal temporal lobe morphology + 0
                    Cerebral cortex with spongiform changes 0
                    Cerebral cortical atrophy + 0
                    Cerebral cortical microinfarct 0
                    Cortical dysplasia + 0
                    Cortical tubers 0
                    Hypoplasia of the frontal lobes 0
                    Neuronal loss in the cerebral cortex 0
                    Open operculum 0
                    Small cerebral cortex + 0
                    Swollen achromatic neurons in the cerebral cortex 0
                    Thick cerebral cortex + 0
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