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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

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Accession:HP:0002380 term browser browse the term
Definition:Fasciculations are observed as small, local, involuntary muscle contractions (twitching) visible under the skin. Fasciculations result from increased irritability of an axon (which in turn is often a manifestation of disease of a motor neuron). This leads to sporadic discharges of all the muscle fibers controlled by the axon in isolation from other motor units.
Comment:This finding can be visible clinically and can be demonstrated by electromyography (EMG).
Synonyms:exact_synonym: Fasciculation;   Muscle fasciculation;   Muscle twitch
 alt_id: HP:0002468;   HP:0007092
 xref: MESH:D005207;   SNOMEDCT_US:82470000;   UMLS:C0015644

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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system physiology 0
          Abnormality of movement 0
            Involuntary movements 0
              Fasciculations 0
                Facial-lingual fasciculations + 0
                Limb fasciculations 0
                Tongue fasciculations 0
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