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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Pseudobulbar affect
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Accession:HP:0002193 term browser browse the term
Definition:Pseudobulbar affect (PBA) is characterized by uncontrolled crying or laughing which may be disproportionate or inappropriate to the social context. Thus, there is a disparity between the patient's emotional expression and his or her emotional experience.
Comment:Terminology has been varied and somewhat confusing, including involuntary emotional expression disorder, emotional lability, emotional dysregulation, pathological laughter and crying, emotional dysregulation, emotional incontinence, and emotionalism. PBA may be encountered in the setting of amyotrophic lateral sclerosis, extrapyramidal and cerebellar disorders (Parkinson disease, multiple system atrophy, progressive supranuclear palsy), multiple sclerosis, traumatic brain injury, Alzheimer disease and other dementias, stroke, and brain tumors.
Synonyms:exact_synonym: Pseudobulbar behavioral symptoms;   Pseudobulbar behavioural symptoms
 xref: UMLS:C4025720


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Path 1
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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system physiology 0
          Pseudobulbar signs 0
            Pseudobulbar affect 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system physiology 0
          Abnormality of mental function 0
            Atypical behavior 0
              Pseudobulbar affect 0
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