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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Neurofibrillary tangles
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Accession:HP:0002185 term browser browse the term
Definition:Pathological protein aggregates formed by hyperphosphorylation of a microtubule-associated protein known as tau, causing it to aggregate in an insoluble form.
Synonyms:exact_synonym: Neurofibrillary tangles composed of disordered microtubules in neurons;   Paired helical filaments
 alt_id: HP:0003132;   HP:0007070
 xref: MESH:D016874;   SNOMEDCT_US:85775002;   UMLS:C0085400


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the nervous system 0
        Abnormal nervous system morphology 0
          Morphological central nervous system abnormality 0
            Abnormality of brain morphology 0
              Abnormal forebrain morphology 0
                Abnormal cerebral morphology 0
                  Cerebral inclusion bodies 0
                    Neurofibrillary tangles 0
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