Neurofibrillary tangles - Ontology Report - Rat Genome Database

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HUMAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.

Term:	Neurofibrillary tangles	go back to main search page
Accession:	HP:0002185	browse the term
Definition:	Pathological protein aggregates formed by hyperphosphorylation of a microtubule-associated protein known as tau, causing it to aggregate in an insoluble form.
Synonyms:	exact_synonym:	Neurofibrillary tangles composed of disordered microtubules in neurons; Paired helical filaments
	alt_id:	HP:0003132; HP:0007070
	xref:	MESH:D016874; SNOMEDCT_US:85775002; UMLS:C0085400

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Term paths to the root

Path 1
Term	Annotations
Human phenotype	0
Phenotypic abnormality	0
Abnormality of the nervous system	0
Abnormal nervous system morphology	0
Morphological central nervous system abnormality	0
Abnormality of brain morphology	0
Abnormal forebrain morphology	0
Abnormal cerebral morphology	0
Cerebral inclusion bodies	0
Neurofibrillary tangles	0

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