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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

Term:Premature rupture of membranes
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Accession:HP:0001788 term browser browse the term
Definition:Premature rupture of membranes (PROM) is a condition which occurs in pregnancy when the amniotic sac ruptures more than an hour before the onset of labor.
Synonyms:alt_id: HP:0002163
 xref: MESH:D005322;   SNOMEDCT_US:237266003;   SNOMEDCT_US:44223004;   UMLS:C0015944

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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of prenatal development or birth 0
        Abnormal delivery 0
          Premature rupture of membranes 0
            Premature birth following premature rupture of fetal membranes 0
            Preterm premature rupture of membranes 0
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