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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Parakeratosis
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Accession:HP:0001036 term browser browse the term
Definition:Abnormal formation of the keratinocytes of the epidermis characterized by persistence of nuclei, incomplete formation of keratin, and moistness and swelling of the keratinocytes.
Comment:Persistence of the nuclei of keratinocytes as they rise into the stratum corneum of the epidermis. Parakeratosis is observed as scaling in many conditions such as psoriasis.
Synonyms:xref: SNOMEDCT_US:200766001;   SNOMEDCT_US:65068000;   UMLS:C0030436


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  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the integument 0
        Abnormality of the skin 0
          Abnormal skin morphology 0
            Thickened skin 0
              Epidermal thickening 0
                Parakeratosis 0
                  Hyperparakeratosis 0
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