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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Palmoplantar hyperkeratosis
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Accession:HP:0000972 term browser browse the term
Definition:Abnormal thickening of the skin localized to the palm of the hand and the sole of the foot.
Comment:The terms hyperkeratosis and keratoderma have been used interchangeably throughout the literature.
Synonyms:exact_synonym: Hyperkeratosis of palms and soles;   Hyperkeratosis of the palms and soles;   Palmoplantar keratoses;   Palmoplantar keratosis;   Thick palms and soles;   Thickened palms and soles;   Thickening of the outer layer of the skin of the palms and soles
 alt_id: HP:0007548
 xref: SNOMEDCT_US:706885006;   UMLS:C0022596


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Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of limbs 0
        Abnormality of the lower limb 0
          Abnormal foot morphology 0
            Abnormality of the plantar skin of foot 0
              Plantar hyperkeratosis 0
                Palmoplantar hyperkeratosis 0
                  Congenital palmoplantar hyperkeratosis 0
                  Congenital symmetrical palmoplantar keratosis 0
                  Diffuse palmoplantar hyperkeratosis 0
                  Focal friction-related palmoplantar hyperkeratosis 0
                  Honeycomb palmoplantar hyperkeratosis 0
                  Nonepidermolytic palmoplantar hyperkeratosis 0
                  Palmoplantar keratoderma 0
                  Patchy palmoplantar hyperkeratosis 0
                  Punctate palmoplantar hyperkeratosis 0
                  Spinous keratoses of palms and soles 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the integument 0
        Abnormality of the skin 0
          Abnormal skin morphology 0
            Thickened skin 0
              Epidermal thickening 0
                Hyperkeratosis 0
                  Plantar hyperkeratosis 0
                    Palmoplantar hyperkeratosis 0
                      Congenital palmoplantar hyperkeratosis 0
                      Congenital symmetrical palmoplantar keratosis 0
                      Diffuse palmoplantar hyperkeratosis 0
                      Focal friction-related palmoplantar hyperkeratosis 0
                      Honeycomb palmoplantar hyperkeratosis 0
                      Nonepidermolytic palmoplantar hyperkeratosis 0
                      Palmoplantar keratoderma 0
                      Patchy palmoplantar hyperkeratosis 0
                      Punctate palmoplantar hyperkeratosis 0
                      Spinous keratoses of palms and soles 0
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