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The Human Phenotype Ontology (HPO) is downloaded weekly from The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at

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Accession:HP:0000969 term browser browse the term
Definition:An abnormal accumulation of fluid beneath the skin, or in one or more cavities of the body.
Comment:Edema may be related to one or more of the following factors: 1) increased capillary hydrostatic pressure, 2) decreased osmotic pressure of plasma, 3) decreased tissue tension and lymphatic drainage, 4) increased osmotic pressure of tissue fluids, and 5) increased capillary permeability.
Synonyms:exact_synonym: Dropsy;   Fluid retention;   Hydrops;   Oedema;   Water retention
 alt_id: HP:0000990
 xref: EFO:0009373;   MESH:D004487;   SNOMEDCT_US:20741006;   SNOMEDCT_US:267038008;   SNOMEDCT_US:423666004;   SNOMEDCT_US:79654002;   UMLS:C0013604

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Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of metabolism/homeostasis 0
        Abnormal homeostasis 0
          Abnormality of fluid regulation 0
            Edema 0
              Angioedema 0
              Cerebral edema 0
              Corneal stromal edema 0
              Edema of the dorsum of hands 0
              Edema of the upper limbs 0
              Facial edema + 0
              Generalized edema + 0
              Genital edema 0
              Hydrops fetalis + 0
              Hyperkeratosis over edematous areas 0
              Hypoproteinemic edema 0
              Increased nuchal translucency 0
              Intestinal edema + 0
              Joint swelling 0
              Laryngeal edema 0
              Lymphedema + 0
              Macular edema + 0
              Muscular edema 0
              Peau d'orange 0
              Pedal edema + 0
              Peripheral edema 0
              Pharyngeal edema 0
              Pleural effusion + 0
              Pulmonary edema 0
              Tongue edema 0
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