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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of cation channel activity
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Accession:GO:2001259 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of cation channel activity.
Synonyms:exact_synonym: positive regulation of cation diffusion facilitator activity;   positive regulation of nonselective cation channel activity


show annotations for term's descendants           Sort by:
positive regulation of cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO (PMID:19815520), (PMID:19943616) RGD PMID:19815520 PMID:19943616 NCBI chr17:62,835,055...62,902,331
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Adrb1 adrenoceptor beta 1 IDA RGD PMID:22505670 RGD:6893581 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Ank2 ankyrin 2 involved_in ISO (PMID:19805355), (PMID:20610380) RGD PMID:19805355 PMID:20610380 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Ank3 ankyrin 3 involved_in IMP PMID:18180363 BHF-UCL PMID:18180363 RGD:6767295 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Asic2 acid sensing ion channel subunit 2 IDA RGD PMID:12736332 RGD:1298620 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424 		JBrowse link
G Ctss cathepsin S involved_in ISO (PMID:22864553) RGD PMID:22864553 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:30990108) RGD PMID:30990108 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO (PMID:30990108) RGD PMID:30990108 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IDA RGD PMID:20806410 RGD:9686372 NCBI chr 2:51,228,710...51,632,806
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta acts_upstream_of_or_within ISO MGI:1933754 (PMID:18981174) RGD PMID:18981174 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IMP RGD PMID:23785408 RGD:7296920 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:1338071 (PMID:18981174) RGD PMID:18981174 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:19359367 RGD:9743912 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Pirt phosphoinositide-interacting regulator of transient receptor potential channels acts_upstream_of_or_within ISO MGI:3834636 (PMID:18455988) RGD PMID:18455988 NCBI chr10:51,613,202...51,628,108
Ensembl chr10:51,613,126...51,632,264 		JBrowse link
G Stac SH3 and cysteine rich domain involved_in ISO (PMID:27149520) RGD PMID:27149520 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008 		JBrowse link
activation of store-operated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate-beta-hydroxylase involved_in ISO (PMID:22586105) RGD PMID:22586105 NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Cracr2a calcium release activated channel regulator 2A involved_in ISS
ISO		 GO_REF:0000024
(PMID:20418871)
(PMID:27016526)		 UniProt
RGD		 PMID:20418871 PMID:27016526 GO_REF:0000024 NCBI chr 4:160,428,987...160,517,427
Ensembl chr 4:160,408,077...160,518,107 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within ISO (PMID:15611229) RGD PMID:15611229 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in IMP
ISO
ISS		 (PMID:16005298), (PMID:26322679), (PMID:28219928)
GO_REF:0000024		 RGD
UniProt		 PMID:16005298 PMID:26322679 PMID:28219928 PMID:21541286 GO_REF:0000024, RGD:7175076 NCBI chr 1:166,067,450...166,230,733
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Stim2 stromal interaction molecule 2 involved_in IMP
ISO		 (PMID:17905723), (PMID:18160041) RGD PMID:17905723 PMID:18160041 PMID:21541286 RGD:7175076 NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179 		JBrowse link
G Stimate STIM activating enhancer involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr16:6,013,392...6,070,829
Ensembl chr16:6,013,369...6,071,816 		JBrowse link
positive regulation of delayed rectifier potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A involved_in IDA
ISO		 PMID:8301666
(PMID:19646991), (PMID:8301666)		 RGD PMID:8301666 PMID:19646991 PMID:8301666 RGD:10047161 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
positive regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IDA PMID:25533460 BHF-UCL PMID:25533460 RGD:11059570 NCBI chr17:82,473,097...82,818,564
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 involved_in IMP PMID:10666413 RGD
UniProt		 PMID:22187436 PMID:10666413 RGD:13514092, RGD:13673808 NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Fgf14 fibroblast growth factor 14 acts_upstream_of_or_within IMP PMID:23831029 MGI PMID:23831029 RGD:10047342 NCBI chr15:107,442,800...108,086,486
Ensembl chr15:101,045,036...101,679,900 		JBrowse link
G Nipsnap2 nipsnap homolog 2 involved_in ISO (PMID:22627147) RGD PMID:22627147 NCBI chr12:32,542,171...32,580,345
Ensembl chr12:26,911,723...26,944,166 		JBrowse link
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin-associated protein 1 involved_in IDA
ISO		 PMID:12873381
(PMID:15379999)		 RGD PMID:15379999 PMID:12873381 RGD:6482800 NCBI chr10:85,778,267...85,786,553
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Htt huntingtin involved_in ISO (PMID:12873381) RGD PMID:12873381 NCBI chr14:80,070,456...80,219,668
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:16223735) RGD PMID:16223735 NCBI chr14:5,541,821...5,585,140
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
positive regulation of large conductance calcium-activated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gal galanin and GMAP prepropeptide involved_in ISO (PMID:24602615) RGD PMID:24602615 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Galr2 galanin receptor 2 involved_in ISO (PMID:24602615) RGD PMID:24602615 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:23407708 RGD:7777099 NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
positive regulation of proton-transporting ATP synthase activity, rotational mechanism term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase involved_in ISS
ISO		 GO_REF:0000024
(PMID:30530489)		 UniProt
RGD		 PMID:30530489 GO_REF:0000024 NCBI chr 2:82,603,086...82,618,325
Ensembl chr 2:82,603,009...82,618,308 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked involved_in ISO (PMID:21106936) RGD PMID:21106936 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667
Ensembl chr10:27,128,610...27,146,667 		JBrowse link
positive regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 involved_in ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 involved_in ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 6:12,845,170...12,857,830
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calm3 calmodulin 3 involved_in ISO (PMID:20226167) RGD PMID:20226167 NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in ISO (PMID:17023043) RGD PMID:17023043 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISO (PMID:11035031) RGD PMID:11035031 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Jph2 junctophilin 2 involved_in ISO (PMID:20095964) RGD PMID:20095964 NCBI chr 3:151,994,768...152,058,941
Ensembl chr 3:151,994,778...152,058,904 		JBrowse link
G Trdn triadin involved_in ISO (PMID:15041652), (PMID:15731460) RGD PMID:15041652 PMID:15731460 NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595 		JBrowse link
positive regulation of store-operated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IMP RGD PMID:20844246 RGD:8801954 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Casq1 calsequestrin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27185316), (PMID:28895244)		 UniProt
RGD		 PMID:27185316 PMID:28895244 GO_REF:0000024 NCBI chr13:87,203,021...87,212,710
Ensembl chr13:84,670,649...84,680,339 		JBrowse link
G Cracr2a calcium release activated channel regulator 2A acts_upstream_of ISO MGI:1925542 (PMID:20418871) RGD PMID:20418871 NCBI chr 4:160,428,987...160,517,427
Ensembl chr 4:160,408,077...160,518,107 		JBrowse link
positive regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IDA RGD PMID:20478999 RGD:13514093 NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 IDA RGD PMID:12821675 RGD:737839 NCBI chr 3:57,315,900...57,578,271
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in IMP PMID:23699505 ARUK-UCL PMID:23699505 RGD:13792535 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Ehd3 EH-domain containing 3 involved_in ISO (PMID:25825486) RGD PMID:25825486 NCBI chr 6:21,640,861...21,665,601
Ensembl chr 6:21,639,290...21,665,236 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187 RGD:7243967 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:14679187 RGD:7243967 NCBI chr11:45,003,468...45,015,942
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA RGD PMID:14679187 RGD:7243967 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G S100a1 S100 calcium binding protein A1 IDA RGD PMID:19657060 RGD:7205633 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544 		JBrowse link
G Stac SH3 and cysteine rich domain involved_in ISO (PMID:29467163) RGD PMID:29467163 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008 		JBrowse link
G Stac2 SH3 and cysteine rich domain 2 involved_in ISO (PMID:29467163) RGD PMID:29467163 NCBI chr10:83,032,418...83,048,260
Ensembl chr10:83,032,417...83,048,260 		JBrowse link
G Stac3 SH3 and cysteine rich domain 3 involved_in ISO (PMID:27621462), (PMID:29467163) RGD PMID:27621462 PMID:29467163 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589 		JBrowse link
positive regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:12183335 RGD:728122 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 IMP RGD PMID:22056818 RGD:14390155 NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585 		JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 IDA RGD PMID:21943416 RGD:7242916 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682 		JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 IDA RGD PMID:21943417 RGD:12910700 NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744 		JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 IDA RGD PMID:21943417 RGD:12910700 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IMP RGD PMID:7568179 RGD:12910723 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153 		JBrowse link
G Lrrc26 leucine rich repeat containing 26 involved_in ISO (PMID:22547800) RGD PMID:22547800 NCBI chr 3:8,102,361...8,103,687
Ensembl chr 3:8,102,361...8,103,687 		JBrowse link
G Lrrc38 leucine rich repeat containing 38 involved_in ISO (PMID:22547800) RGD PMID:22547800 NCBI chr 5:155,685,495...155,707,578
Ensembl chr 5:155,685,495...155,707,578 		JBrowse link
G Lrrc52 leucine rich repeat containing 52 involved_in ISO (PMID:22547800) RGD PMID:22547800 NCBI chr13:79,597,244...79,620,640
Ensembl chr13:79,597,245...79,620,640 		JBrowse link
G Lrrc55 leucine rich repeat containing 55 involved_in ISO (PMID:22547800) RGD PMID:22547800 NCBI chr 3:70,269,908...70,280,651
Ensembl chr 3:70,265,936...70,278,639 		JBrowse link
positive regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf13 fibroblast growth factor 13 involved_in ISS
ISO		 GO_REF:0000024
(PMID:36696443)		 UniProt
RGD		 PMID:36696443 GO_REF:0000024 NCBI chr  X:142,312,381...142,838,581
Ensembl chr  X:137,276,511...137,800,391 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:24097558 RGD:39939085 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Kif5b kinesin family member 5B IMP RGD PMID:24198377 RGD:11073607 NCBI chr17:56,185,386...56,222,990
Ensembl chr17:51,489,944...51,527,508 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:36696443)		 UniProt
RGD		 PMID:36696443 GO_REF:0000024 NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    positive regulation of biological process 6756
      positive regulation of transport 1090
        positive regulation of transporter activity 117
          positive regulation of ion transmembrane transporter activity 112
            positive regulation of cation channel activity 67
              positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 3
              positive regulation of large conductance calcium-activated potassium channel activity 3
              positive regulation of proton-transporting ATP synthase activity, rotational mechanism 2
              positive regulation of ryanodine-sensitive calcium-release channel activity 7
              positive regulation of store-operated calcium channel activity + 8
              positive regulation of voltage-gated calcium channel activity + 15
              positive regulation of voltage-gated potassium channel activity + 12
              positive regulation of voltage-gated sodium channel activity 4
Path 2
Term Annotations click to browse term
  biological_process 20546
    localization 5709
      establishment of localization 5057
        transport 4749
          regulation of transport 1961
            regulation of transmembrane transport 574
              regulation of transmembrane transporter activity 240
                regulation of monoatomic ion transmembrane transporter activity 232
                  positive regulation of ion transmembrane transporter activity 112
                    positive regulation of cation channel activity 67
                      positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 3
                      positive regulation of large conductance calcium-activated potassium channel activity 3
                      positive regulation of proton-transporting ATP synthase activity, rotational mechanism 2
                      positive regulation of ryanodine-sensitive calcium-release channel activity 7
                      positive regulation of store-operated calcium channel activity + 8
                      positive regulation of voltage-gated calcium channel activity + 15
                      positive regulation of voltage-gated potassium channel activity + 12
                      positive regulation of voltage-gated sodium channel activity 4
paths to the root