Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cation channel activity
go back to main search page
Accession:GO:2001257 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cation channel activity.
Synonyms:exact_synonym: regulation of cation diffusion facilitator activity;   regulation of nonselective cation channel activity



show annotations for term's descendants           Sort by:
activation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stim1 stromal interaction molecule 1 IMP RGD PMID:21541286 RGD:7175076 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Stim2 stromal interaction molecule 2 IMP RGD PMID:21541286 RGD:7175076 NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
JBrowse link
negative regulation of cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 IDA RGD PMID:20624795 RGD:6849299 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Fgf12 fibroblast growth factor 12 IDA RGD PMID:12401812 RGD:6484231 NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607
JBrowse link
negative regulation of delayed rectifier potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 IDA
IMP
RGD PMID:8183366 PMID:8799886 RGD:61642, RGD:9743956 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Mtnr1b melatonin receptor 1B IDA RGD PMID:14962062 RGD:9588668 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737
JBrowse link
negative regulation of inward rectifier potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx27 sorting nexin 27 IDA RGD PMID:21422294 RGD:8554349 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906
JBrowse link
negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabp1 calcium binding protein 1 IDA RGD PMID:17960496 RGD:7207144 NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein IMP RGD PMID:24751537 RGD:10047103 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 IMP RGD PMID:26584289 RGD:155804278 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:15937148 RGD:9835002 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
negative regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187 PMID:21943416 PMID:21943417 RGD:7243967, RGD:7242916, RGD:12910700 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:19219384 PMID:21943416 PMID:14679187 RGD:7243947, RGD:7242916, RGD:7243967 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA RGD PMID:14679187 RGD:7243967 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
positive regulation of cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IDA RGD PMID:22505670 RGD:6893581 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Asic2 acid sensing ion channel subunit 2 IDA RGD PMID:12736332 RGD:1298620 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IDA RGD PMID:20806410 RGD:9686372 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IMP RGD PMID:23785408 RGD:7296920 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:19359367 RGD:9743912 NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
positive regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IMP RGD PMID:22187436 RGD:13514092 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
positive regulation of large conductance calcium-activated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:23407708 RGD:7777099 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
positive regulation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IMP RGD PMID:20844246 RGD:8801954 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
positive regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IDA RGD PMID:20478999 RGD:13514093 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 IDA RGD PMID:12821675 RGD:737839 NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187 RGD:7243967 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:14679187 RGD:7243967 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA RGD PMID:14679187 RGD:7243967 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G S100a1 S100 calcium binding protein A1 IDA RGD PMID:19657060 RGD:7205633 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
JBrowse link
positive regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IMP RGD PMID:12183335 RGD:728122 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 IMP RGD PMID:22056818 RGD:14390155 NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585
JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 IDA RGD PMID:21943416 RGD:7242916 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682
JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 IDA RGD PMID:21943417 RGD:12910700 NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744
JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 IDA RGD PMID:21943417 RGD:12910700 NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IMP RGD PMID:7568179 RGD:12910723 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
positive regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:24097558 RGD:39939085 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Kif5b kinesin family member 5B IMP RGD PMID:24198377 RGD:11073607 NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508
JBrowse link
regulation of acetylcholine-gated cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit IMP RGD PMID:11904236 RGD:704387 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 IMP RGD PMID:18322004 RGD:7207845 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
regulation of kainate selective glutamate receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grip1 glutamate receptor interacting protein 1 IMP RGD PMID:12597860 RGD:152995391 NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273
JBrowse link
G Pick1 protein interacting with PRKCA 1 IMP RGD PMID:12597860 RGD:152995391 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link
regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IDA RGD PMID:15628869 RGD:7241270 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 IDA RGD PMID:15628869 RGD:7241270 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 IDA RGD PMID:15628869 RGD:7241270 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
regulation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calm1 calmodulin 1 IC RGD PMID:23109337 RGD:7241220 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 IC RGD PMID:23109337 RGD:7241220 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 IC RGD PMID:23109337 RGD:7241220 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Pla2g6 phospholipase A2 group VI IMP RGD PMID:12547829 RGD:6482757 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Plcg1 phospholipase C, gamma 1 IMP RGD PMID:17432954 RGD:2299884 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabp1 calcium binding protein 1 IDA RGD PMID:17224447 RGD:7207146 NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IMP RGD PMID:17196942 RGD:1598976 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 IDA RGD PMID:12042350 RGD:632406 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    cellular process 18312
      transmembrane transport 1602
        monoatomic ion transmembrane transport 1025
          regulation of monoatomic ion transmembrane transport 311
            regulation of monoatomic cation transmembrane transport 273
              regulation of cation channel activity 43
                negative regulation of cation channel activity + 13
                positive regulation of cation channel activity + 24
                regulation of acetylcholine-gated cation channel activity + 1
                regulation of delayed rectifier potassium channel activity + 2
                regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity + 0
                regulation of inward rectifier potassium channel activity + 1
                regulation of kainate selective glutamate receptor activity 2
                regulation of large conductance calcium-activated potassium channel activity + 1
                regulation of osmolarity-sensing cation channel activity + 0
                regulation of proton-transporting ATP synthase activity, rotational mechanism + 0
                regulation of ryanodine-sensitive calcium-release channel activity + 3
                regulation of store-operated calcium channel activity + 8
                regulation of voltage-gated calcium channel activity + 16
                regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization + 0
                regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization + 0
                regulation of voltage-gated sodium channel activity + 2
Path 2
Term Annotations click to browse term
  biological_process 19872
    localization 5633
      establishment of localization 4939
        transport 4625
          transmembrane transport 1602
            monoatomic ion transmembrane transport 1025
              monoatomic cation transmembrane transport 864
                regulation of monoatomic cation transmembrane transport 273
                  regulation of cation channel activity 43
                    negative regulation of cation channel activity + 13
                    positive regulation of cation channel activity + 24
                    regulation of acetylcholine-gated cation channel activity + 1
                    regulation of delayed rectifier potassium channel activity + 2
                    regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity + 0
                    regulation of inward rectifier potassium channel activity + 1
                    regulation of kainate selective glutamate receptor activity 2
                    regulation of large conductance calcium-activated potassium channel activity + 1
                    regulation of osmolarity-sensing cation channel activity + 0
                    regulation of proton-transporting ATP synthase activity, rotational mechanism + 0
                    regulation of ryanodine-sensitive calcium-release channel activity + 3
                    regulation of store-operated calcium channel activity + 8
                    regulation of voltage-gated calcium channel activity + 16
                    regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization + 0
                    regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization + 0
                    regulation of voltage-gated sodium channel activity + 2
paths to the root