Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of apoptotic signaling pathway
go back to main search page
Accession:GO:2001235 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
Synonyms:exact_synonym: positive regulation of apoptotic signalling pathway
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe


show annotations for term's descendants           Sort by:
positive regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10845921) Ensembl
MGI		 PMID:10845921 GO_REF:0000107 NCBI chr14:49,467,186...49,485,845
Ensembl chr14:49,468,877...49,485,850 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16183742) Ensembl
MGI		 PMID:16183742 GO_REF:0000107 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364 		JBrowse link
G BID BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8918887) Ensembl
MGI		 PMID:8918887 GO_REF:0000107 NCBI chr 5:69,849,007...69,874,647
Ensembl chr 5:69,849,002...69,875,853 		JBrowse link
G BMF Bcl2 modifying factor acts_upstream_of_or_within ISO (PMID:11546872) MGI PMID:11546872 NCBI chr 1:131,178,021...131,199,668
Ensembl chr 1:131,178,315...131,200,393 		JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta acts_upstream_of_or_within ISO (PMID:17367784) MGI PMID:17367784 NCBI chr18:50,862,225...50,956,263
Ensembl chr18:50,861,466...50,956,225 		JBrowse link
G CASP2 caspase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16183742) Ensembl
MGI
TreeGrafter		 PMID:16183742 GO_REF:0000107 GO_REF:0000118 NCBI chr18:6,946,432...6,966,088
Ensembl chr18:6,941,937...6,966,061 		JBrowse link
G CLCN1 chloride voltage-gated channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:6,902,540...6,941,530
Ensembl chr18:6,902,542...6,940,449 		JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:89,257,603...89,480,414
Ensembl chr 5:89,267,944...89,479,712 		JBrowse link
G CTSC cathepsin C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20435891) Ensembl
MGI		 PMID:20435891 GO_REF:0000107 NCBI chr 9:21,726,628...21,761,796
Ensembl chr 9:21,722,036...21,761,516 		JBrowse link
G CTSH cathepsin H involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:20435891) Ensembl
MGI
GO_Central		 PMID:20435891 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:48,084,882...48,106,072
Ensembl chr 7:48,083,572...48,106,072 		JBrowse link
G CTSK cathepsin K involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:98,389,459...98,404,969
Ensembl chr 4:98,391,428...98,404,961 		JBrowse link
G CTSL cathepsin L involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618 		JBrowse link
G CTSS cathepsin S involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:98,415,273...98,442,952
Ensembl chr 4:98,417,883...98,442,950 		JBrowse link
G CTSV cathepsin V involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr10:25,202,360...25,208,058
Ensembl chr10:25,202,389...25,209,210 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,660...261,859,022 		JBrowse link
G DAXX death domain associated protein acts_upstream_of_or_within ISO (PMID:10684855) MGI PMID:10684855 NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110 		JBrowse link
G EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15680327) Ensembl
MGI		 PMID:15680327 GO_REF:0000107 NCBI chr 7:5,368,341...5,390,665
Ensembl chr 7:5,370,967...5,390,633 		JBrowse link
G FAS Fas cell surface death receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G IFNB1 interferon beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495 		JBrowse link
G IL19 interleukin 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12370360) Ensembl
MGI		 PMID:12370360 GO_REF:0000107 NCBI chr 9:67,469,519...67,479,597
Ensembl chr 9:67,469,524...67,479,813 		JBrowse link
G INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21750715) Ensembl
MGI		 PMID:21750715 GO_REF:0000107 NCBI chr12:51,923,764...51,931,875
Ensembl chr12:51,924,902...51,931,873 		JBrowse link
G ING5 inhibitor of growth family member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21750715) Ensembl
MGI
TreeGrafter		 PMID:21750715 GO_REF:0000107 GO_REF:0000118 NCBI chr15:140,264,708...140,279,020
Ensembl chr15:140,264,766...140,279,010 		JBrowse link
G INHBB inhibin subunit beta B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20454446) Ensembl
MGI		 PMID:20454446 GO_REF:0000107 NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405 		JBrowse link
G JAK2 Janus kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15012602) Ensembl
MGI		 PMID:15012602 GO_REF:0000107 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148 		JBrowse link
G MAGED1 MAGE family member D1 acts_upstream_of_or_within ISO (PMID:17488777)
(PMID:19268530)		 MGI PMID:17488777 PMID:19268530 NCBI chr  X:45,258,761...45,329,282
Ensembl chr  X:45,258,829...45,329,272 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO (PMID:16458303) MGI PMID:16458303 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16458303) Ensembl
MGI		 PMID:16458303 GO_REF:0000107 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (PMID:14517295) MGI PMID:14517295 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G NFATC4 nuclear factor of activated T cells 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20530871) Ensembl
MGI		 PMID:20530871 GO_REF:0000107 NCBI chr 7:74,918,982...74,929,688
Ensembl chr 7:74,918,984...74,929,600 		JBrowse link
G NGFR nerve growth factor receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10764727) Ensembl
MGI		 PMID:10764727 GO_REF:0000107 NCBI chr12:25,699,410...25,720,355
Ensembl chr12:25,699,427...25,720,356 		JBrowse link
G NKX3-1 NK3 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:7,783,296...7,787,036
Ensembl chr14:7,783,323...7,787,033 		JBrowse link
G OSM oncostatin M acts_upstream_of_or_within ISO (PMID:15012602) MGI PMID:15012602 NCBI chr14:47,242,767...47,246,836
Ensembl chr14:47,242,774...47,246,838 		JBrowse link
G PDCD7 programmed cell death 7 acts_upstream_of_or_within ISO (PMID:10037816) MGI PMID:10037816 NCBI chr 1:163,157,881...163,172,528
Ensembl chr 1:163,156,925...163,170,228 		JBrowse link
G PML PML nuclear body scaffold involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10684855) Ensembl
MGI		 PMID:10684855 GO_REF:0000107 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105 		JBrowse link
G PRKCD protein kinase C delta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15731106) Ensembl
MGI		 PMID:15731106 GO_REF:0000107 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G PTEN phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:9778245) MGI PMID:9778245 NCBI chr14:99,929,590...100,021,619 JBrowse link
G RPS3 ribosomal protein S3 involved_in IEA
IBA		 TreeGrafter
Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:9,612,939...9,630,404
Ensembl chr 9:9,624,990...9,630,401 		JBrowse link
G SOCS2 suppressor of cytokine signaling 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:89,581,081...89,587,424
Ensembl chr 5:89,581,090...89,584,581 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G TP63 tumor protein p63 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9774969) Ensembl
MGI		 PMID:9774969 GO_REF:0000107 NCBI chr13:127,115,990...127,347,082
Ensembl chr13:127,116,105...127,347,068 		JBrowse link
G TP73 tumor protein p73 acts_upstream_of_or_within ISO (PMID:16044147) MGI PMID:16044147 NCBI chr 6:65,169,770...65,228,997
Ensembl chr 6:65,182,456...65,228,990 		JBrowse link
G TPD52L1 TPD52 like 1 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:37,667,476...37,761,670
Ensembl chr 1:37,667,150...37,761,760 		JBrowse link
G TRAF7 TNF receptor associated factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:39,811,803...39,828,450
Ensembl chr 3:39,810,606...39,828,395 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:23,047,048...23,062,974
Ensembl chr 7:23,047,520...23,062,487 		JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:140,171,134...140,184,126
Ensembl chr15:140,171,143...140,184,121 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (PMID:22240901) MGI PMID:22240901 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:77,863,655...77,940,944
Ensembl chr13:77,863,701...77,945,468 		JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:49,063,813...49,222,274
Ensembl chr 3:49,063,991...49,198,664 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:96,769,862...96,847,136
Ensembl chr 6:96,770,253...96,847,125 		JBrowse link
G RNF183 ring finger protein 183 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:253,924,122...253,966,702
Ensembl chr 1:253,925,677...253,933,791 		JBrowse link
G SERINC3 serine incorporator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12486168) Ensembl
MGI		 PMID:12486168 GO_REF:0000107 NCBI chr17:46,904,841...46,924,842
Ensembl chr17:46,895,402...46,924,792 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G SPOP speckle type BTB/POZ protein acts_upstream_of_or_within ISO (PMID:20811152) MGI PMID:20811152 NCBI chr12:25,792,621...25,860,630
Ensembl chr12:25,792,630...25,860,595 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G AGTR2 angiotensin II receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10753917) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:10753917 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:130,645,427...130,653,317
Ensembl chr 4:130,645,216...130,657,995 		JBrowse link
G BCL2L14 BCL2 like 14 involved_in ISO (PMID:11054413) UniProt PMID:11054413 NCBI chr 5:60,334,813...60,357,935
Ensembl chr 5:60,332,451...60,357,897 		JBrowse link
G BID BH3 interacting domain death agonist involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter
UniProt		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:69,849,007...69,874,647
Ensembl chr 5:69,849,002...69,875,853 		JBrowse link
G CASP8 caspase 8 acts_upstream_of_or_within ISO (PMID:16183742) MGI PMID:16183742 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468 		JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:34,058,091...34,121,939
Ensembl chr 6:34,059,081...34,121,264 		JBrowse link
G DEDD2 death effector domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:49,710,948...49,730,457
Ensembl chr 6:49,710,933...49,727,192 		JBrowse link
G FADD Fas associated via death domain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22675671) Ensembl
MGI		 PMID:22675671 GO_REF:0000107 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818 		JBrowse link
G G0S2 G0/G1 switch 2 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:133,287,065...133,288,066
Ensembl chr 9:133,287,325...133,287,742 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980 		JBrowse link
G HYAL2 hyaluronidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19366691) Ensembl
MGI		 PMID:19366691 GO_REF:0000107 NCBI chr13:32,805,220...32,813,684
Ensembl chr13:32,805,227...32,815,333 		JBrowse link
G ITM2C integral membrane protein 2C involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:131,614,887...131,627,428
Ensembl chr15:131,614,743...131,628,619 		JBrowse link
G LTBR lymphotoxin beta receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:64,271,372...64,278,422
Ensembl chr 5:64,270,310...64,287,523 		JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:133,276,122...133,383,506
Ensembl chr13:133,273,112...133,389,458 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15858817) Ensembl
MGI		 PMID:15858817 GO_REF:0000107 NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196 		JBrowse link
G PML PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8666928) Ensembl
MGI		 PMID:8666928 GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786 		JBrowse link
G RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19136968) Ensembl
MGI		 PMID:19136968 GO_REF:0000107 NCBI chr17:34,784,018...34,801,228
Ensembl chr17:34,784,016...34,801,230 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19498109) Ensembl
MGI		 PMID:19498109 GO_REF:0000107 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699 		JBrowse link
G RUNX3 RUNX family transcription factor 3 acts_upstream_of_or_within ISO (PMID:11955451) MGI PMID:11955451 NCBI chr 6:82,531,203...82,595,044
Ensembl chr 6:82,531,559...82,595,026 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14976225) Ensembl
MGI		 PMID:14976225 GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SIGLEC1 sialic acid binding Ig like lectin 1 acts_upstream_of_or_within ISO (PMID:23408841) MGI PMID:23408841 NCBI chr17:31,994,505...32,021,239
Ensembl chr17:31,994,632...32,021,239 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) ARUK-UCL PMID:20037584 MGI:4438693 NCBI chr 8:30,159,744...30,180,650
Ensembl chr 8:30,159,754...30,180,650 		JBrowse link
G TNF tumor necrosis factor involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:39,166,288...39,168,294
Ensembl chr 3:39,166,298...39,168,302 		JBrowse link
G TNFSF10 TNF superfamily member 10 involved_in
acts_upstream_of_or_within		 ISO (PMID:20097879), (PMID:21525171), (PMID:22266862)
(PMID:15632112)		 UniProt
MGI		 PMID:15632112 PMID:20097879 PMID:21525171 PMID:22266862 NCBI chr13:111,021,952...111,103,060
Ensembl chr13:110,983,298...111,038,324 		JBrowse link
G TNFSF12 TNF superfamily member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,843,026...52,853,328
Ensembl chr12:52,843,026...52,853,325 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IEA Ensembl GO_REF:0000107
G WWOX WW domain containing oxidoreductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNA1 catenin alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22411810) Ensembl
MGI		 PMID:22411810 GO_REF:0000107 NCBI chr 2:140,682,776...140,869,828
Ensembl chr 2:140,682,371...140,871,334 		JBrowse link
G DAPK3 death associated protein kinase 3 involved_in ISO PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 2:74,758,962...74,776,355
Ensembl chr 2:74,759,004...74,775,330 		JBrowse link
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:68,516,666...68,520,025
Ensembl chr 3:68,516,500...68,519,886 		JBrowse link
G INHBA inhibin subunit beta A involved_in ISS UniProt GO_REF:0000024 NCBI chr12:53,115,379...53,117,128
NCBI chr18:52,889,684...52,909,260
Ensembl chr18:52,889,684...52,900,967 		JBrowse link
G JAK3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chr 2:59,905,901...59,926,504
Ensembl chr 2:59,905,919...59,926,495 		JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:15039234) MGI PMID:15039234 NCBI chr12:43,487,098...43,754,205
Ensembl chr12:43,489,813...43,753,969 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12115603) Ensembl
MGI		 PMID:12115603 GO_REF:0000107 NCBI chr 2:5,120,202...5,123,168
Ensembl chr 2:5,119,939...5,123,617 		JBrowse link
G PPP2R1A protein phosphatase 2 scaffold subunit Aalpha acts_upstream_of_or_within ISO (PMID:12944463) MGI PMID:12944463 NCBI chr 6:57,929,520...57,964,948
Ensembl chr 6:57,921,329...57,964,961 		JBrowse link
G PPP2R1B protein phosphatase 2 scaffold subunit Abeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:39,479,040...39,518,773
Ensembl chr 9:39,480,331...39,517,629 		JBrowse link
G RET ret proto-oncogene involved_in ISO (PMID:10921886) UniProt PMID:10921886 NCBI chr14:61,305,818...61,361,416
Ensembl chr14:61,305,841...61,361,412 		JBrowse link
G SRPX sushi repeat containing protein X-linked involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17088259) Ensembl
MGI		 PMID:17088259 GO_REF:0000107 NCBI chr  X:34,075,577...34,198,462
Ensembl chr  X:34,075,579...34,198,467 		JBrowse link
G TGFB2 transforming growth factor beta 2 acts_upstream_of_or_within ISO (PMID:8206089) MGI PMID:8206089 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,539...8,390,341 		JBrowse link
G UNC5B unc-5 netrin receptor B involved_in ISO PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr14:74,120,055...74,208,055
Ensembl chr14:74,120,050...74,205,263 		JBrowse link
G WWOX WW domain containing oxidoreductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19366691) Ensembl
MGI		 PMID:19366691 GO_REF:0000107 NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1B bone morphogenetic protein receptor type 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18363966) Ensembl
MGI		 PMID:18363966 GO_REF:0000107 NCBI chr 8:124,536,648...125,035,841
Ensembl chr 8:124,536,653...124,759,406 		JBrowse link
G FAF1 Fas associated factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8524870) Ensembl
MGI		 PMID:8524870 GO_REF:0000107 NCBI chr 6:161,173,915...161,603,731
Ensembl chr 6:161,166,996...161,603,725 		JBrowse link
G MAL mal, T cell differentiation protein acts_upstream_of_or_within ISO (PMID:12776198) MGI PMID:12776198 NCBI chr 3:46,223,610...46,242,306
Ensembl chr 3:46,181,555...46,242,047 		JBrowse link
G PEA15 proliferation and apoptosis adaptor protein 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10588860) Ensembl
MGI		 PMID:10588860 GO_REF:0000107 NCBI chr 4:90,263,600...90,276,142
Ensembl chr 4:90,263,604...90,276,147 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15705586) BHF-UCL PMID:15705586 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164 		JBrowse link
G PSEN2 presenilin 2 acts_upstream_of_or_within ISO (PMID:8940094) MGI PMID:8940094 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SKIL SKI like proto-oncogene involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10811619) Ensembl
MGI		 PMID:10811619 GO_REF:0000107 NCBI chr13:109,029,831...109,059,176
Ensembl chr13:109,029,952...109,059,173 		JBrowse link
G STK3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20080598) Ensembl
MGI		 PMID:20080598 GO_REF:0000107 NCBI chr 4:38,011,802...38,306,777
Ensembl chr 4:38,011,814...38,306,773 		JBrowse link
G STK4 serine/threonine kinase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20080598) Ensembl
MGI		 PMID:20080598 GO_REF:0000107 NCBI chr17:47,387,594...47,475,705
Ensembl chr17:47,387,600...47,475,718 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,784...131,746,115 		JBrowse link
G TRPS1 transcriptional repressor GATA binding 1 acts_upstream_of_or_within ISO (PMID:18363966) MGI PMID:18363966 NCBI chr 4:22,905,627...23,162,862
Ensembl chr 4:22,905,637...23,159,546 		JBrowse link
G ZSWIM2 zinc finger SWIM-type containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16522193) Ensembl
MGI		 PMID:16522193 GO_REF:0000107 NCBI chr15:91,840,694...91,865,227
Ensembl chr15:91,840,944...91,864,332 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO MMO:0000679 RGD PMID:23729662 RGD:329403056 NCBI chr 4:83,103,768...83,205,015
Ensembl chr 4:83,098,290...83,205,454 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14502238) Ensembl
MGI		 PMID:14502238 GO_REF:0000107 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G BBC3 BCL2 binding component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,046,887 		JBrowse link
G BCAP31 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:124,456,999...124,484,923
Ensembl chr  X:124,457,001...124,484,743 		JBrowse link
G BCL2L11 BCL2 like 11 involved_in ISO (PMID:21671007) UniProt PMID:21671007 NCBI chr 3:45,156,791...45,202,996
Ensembl chr 3:45,160,155...45,201,186 		JBrowse link
G BCLAF1 BCL2 associated transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:27,872,167...27,902,980
Ensembl chr 1:27,872,183...27,902,974 		JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373 		JBrowse link
G BID BH3 interacting domain death agonist involved_in IEA
IBA		 Ensembl
UniProt
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:69,849,007...69,874,647
Ensembl chr 5:69,849,002...69,875,853 		JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:140,171,134...140,184,126
Ensembl chr15:140,171,143...140,184,121 		JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of_or_within ISO (PMID:17938250) MGI PMID:17938250 NCBI chr 3:45,585,188...45,623,240
Ensembl chr 3:45,585,226...45,624,543 		JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G CLU clusterin involved_in ISS UniProt GO_REF:0000024 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G EI24 EI24 autophagy associated transmembrane protein acts_upstream_of_or_within ISO (PMID:17981155) MGI PMID:17981155 NCBI chr 9:52,704,560...52,724,966
Ensembl chr 9:52,704,570...52,720,938 		JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:41,571,054...41,636,058
Ensembl chr 5:41,570,282...41,636,028 		JBrowse link
G FIS1 fission, mitochondrial 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,938,250...8,942,102
Ensembl chr 3:8,937,453...8,946,955 		JBrowse link
G FLCN folliculin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21258407) Ensembl
MGI		 PMID:21258407 GO_REF:0000107 NCBI chr12:61,029,186...61,045,400
Ensembl chr12:61,031,157...61,045,392 		JBrowse link
G GSDME gasdermin E involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:47,524,637...47,583,748
Ensembl chr18:47,526,797...47,583,731 		JBrowse link
G IL19 interleukin 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23468852) Ensembl
MGI		 PMID:23468852 GO_REF:0000107 NCBI chr 9:67,469,519...67,479,597
Ensembl chr 9:67,469,524...67,479,813 		JBrowse link
G IL20RA interleukin 20 receptor subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23468852) Ensembl
MGI		 PMID:23468852 GO_REF:0000107 NCBI chr 1:27,137,545...27,172,341
Ensembl chr 1:27,137,558...27,172,720 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:88,719,886...88,745,922
Ensembl chr 6:88,720,176...88,745,914 		JBrowse link
G MIR15A microRNA mir-15a involved_in ISO (PMID:16166262) BHF-UCL PMID:16166262 NCBI chr11:17,757,463...17,757,541
Ensembl chr11:17,757,460...17,757,554 		JBrowse link
G MIR16-1 microRNA mir-16-1 involved_in ISO (PMID:16166262) BHF-UCL PMID:16166262 NCBI chr13:100,083,329...100,083,405
Ensembl chr13:100,083,329...100,083,405 		JBrowse link
G MIR16-2 microRNA mir-16-2 involved_in ISO (PMID:16166262) BHF-UCL PMID:16166262 NCBI chr11:17,757,606...17,757,684
Ensembl chr11:17,757,601...17,757,687 		JBrowse link
G MIR27B microRNA mir-27b acts_upstream_of_or_within ISO (PMID:31124343) ARUK-UCL PMID:31124343 NCBI chr10:27,079,963...27,080,042
Ensembl chr10:27,079,954...27,080,056 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,466,138...6,483,539
Ensembl chr12:6,466,121...6,483,548 		JBrowse link
G NKX3-1 NK3 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:7,783,296...7,787,036
Ensembl chr14:7,783,323...7,787,033 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,402,781...18,404,411
Ensembl chr 3:18,402,935...18,511,087 		JBrowse link
G PLAGL2 PLAG1 like zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11832486) Ensembl
MGI		 PMID:11832486 GO_REF:0000107 NCBI chr17:35,840,624...35,856,564
Ensembl chr17:35,840,633...35,856,440 		JBrowse link
G PLEKHF1 pleckstrin homology and FYVE domain containing 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:16188880) GO_Central
TreeGrafter
MGI		 PMID:16188880 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:39,786,201...39,797,578
Ensembl chr 6:39,786,199...39,797,583 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:21454712) UniProt PMID:21454712 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,887...161,188,164 		JBrowse link
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12181197) Ensembl
MGI		 PMID:12181197 GO_REF:0000107 NCBI chr15:84,134,273...84,156,596
Ensembl chr15:84,133,687...84,156,508 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:57,280,192...57,284,846
Ensembl chr 2:57,279,857...57,284,849 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10490590) Ensembl
MGI		 PMID:10490590 GO_REF:0000107 NCBI chr 7:74,951,145...74,955,255
Ensembl chr 7:74,951,145...74,955,251 		JBrowse link
G S100A8 S100 calcium binding protein A8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:96,209,670...96,210,603
Ensembl chr 4:96,209,659...96,210,602 		JBrowse link
G S100A9 S100 calcium binding protein A9 involved_in ISO (PMID:19935772) UniProt PMID:19935772 NCBI chr 4:96,236,114...96,238,989 JBrowse link
G SEPTIN4 septin 4 involved_in ISO (PMID:21185211) UniProt PMID:21185211 NCBI chr12:34,772,776...34,785,176 JBrowse link
G SIAH1 siah E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,337,770...36,365,784
Ensembl chr 6:36,342,872...36,371,383 		JBrowse link
G STYXL1 serine/threonine/tyrosine interacting like 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:10,131,508...10,212,611
Ensembl chr 3:10,132,093...10,205,179 		JBrowse link
G TAF6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:20096117) UniProt PMID:20096117 NCBI chr 3:8,017,675...8,026,982
Ensembl chr 3:8,017,675...8,026,888 		JBrowse link
G TMEM120A transmembrane protein 120A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:10,206,581...10,212,612
Ensembl chr 3:10,206,630...10,212,610 		JBrowse link
G TP53 tumor protein p53 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF5A eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) UniProt PMID:15371445 NCBI chr12:52,659,040...52,664,686 JBrowse link
G MIR186 microRNA mir-186 acts_upstream_of ISO (PMID:27714074) ARUK-UCL PMID:27714074 NCBI chr 6:141,943,328...141,943,409
Ensembl chr 6:141,943,328...141,943,409 		JBrowse link
G MSX1 msh homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:5,628,381...5,632,375
Ensembl chr 8:5,628,380...5,632,607 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:131,258,709...131,263,285
Ensembl chr 3:131,258,722...131,263,256 		JBrowse link
G SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 involved_in ISO (MGI:5553386|PMID:24523556) UniProt PMID:24523556 MGI:5553386 NCBI chr 4:129,361,596...129,395,790
Ensembl chr 4:129,357,552...129,395,583 		JBrowse link
G UBB ubiquitin B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17571083) MGI
Ensembl		 PMID:17571083 GO_REF:0000107 NCBI chr12:59,171,258...59,172,841
Ensembl chr12:59,171,289...59,172,841 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBH1 F-box DNA helicase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23361013) MGI
Ensembl		 PMID:23361013 GO_REF:0000107 NCBI chr10:65,060,714...65,108,975
Ensembl chr10:65,060,312...65,108,379 		JBrowse link
G MTCH2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (PMID:26219591) MGI PMID:26219591 NCBI chr 2:14,982,991...15,005,214
Ensembl chr 2:14,983,154...15,005,213 		JBrowse link
G NACC2 NACC family member 2 involved_in IEA Ensembl GO_REF:0000107
G PIAS4 protein inhibitor of activated STAT 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16816390) Ensembl
MGI		 PMID:16816390 GO_REF:0000107 NCBI chr 2:74,702,915...74,729,792
Ensembl chr 2:74,702,945...74,729,775 		JBrowse link
G PLSCR1 phospholipid scramblase 1 acts_upstream_of_or_within ISO (PMID:12509439) MGI PMID:12509439 NCBI chr13:86,836,288...86,869,569
Ensembl chr13:86,834,587...86,869,297 		JBrowse link
G RAD9A RAD9 checkpoint clamp component A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15983387) Ensembl
MGI		 PMID:15983387 GO_REF:0000107 NCBI chr 2:5,123,142...5,129,740
Ensembl chr 2:5,123,134...5,129,703 		JBrowse link
G RPS3 ribosomal protein S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:9,612,939...9,630,404
Ensembl chr 9:9,624,990...9,630,401 		JBrowse link
G SKIL SKI like proto-oncogene involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10811619) Ensembl
MGI		 PMID:10811619 GO_REF:0000107 NCBI chr13:109,029,831...109,059,176
Ensembl chr13:109,029,952...109,059,173 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL26 ribosomal protein L26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:53,548,313...53,553,453
Ensembl chr12:53,548,321...53,553,455 		JBrowse link
G STEAP3 STEAP3 metalloreductase acts_upstream_of_or_within ISO (PMID:18617898) MGI PMID:18617898 NCBI chr15:24,736,556...24,785,376
Ensembl chr15:24,736,594...24,787,865 		JBrowse link
G TP73 tumor protein p73 acts_upstream_of_or_within ISO (PMID:15983387) MGI PMID:15983387 NCBI chr 6:65,169,770...65,228,997
Ensembl chr 6:65,182,456...65,228,990 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOX1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19661248) Ensembl
MGI		 PMID:19661248 GO_REF:0000107 NCBI chr  X:82,540,664...82,575,811
Ensembl chr  X:82,540,667...82,586,532 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22555455) Ensembl
MGI		 PMID:22555455 GO_REF:0000107 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,516 		JBrowse link
G SFPQ splicing factor proline and glutamine rich involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:91,391,552...91,408,236
Ensembl chr 6:91,391,555...91,408,219 		JBrowse link
G SOD1 superoxide dismutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G VNN1 vanin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:31,003,338...31,023,731
Ensembl chr 1:31,000,255...31,024,505 		JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:28386847 RGD:329337357 NCBI chr 4:83,103,768...83,205,015
Ensembl chr 4:83,098,290...83,205,454 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:76,482,027...76,699,354
Ensembl chr 8:76,482,844...76,699,348 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,562,092...98,567,014
Ensembl chr 4:98,534,812...98,567,006 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO RGD PMID:27614125 RGD:329961568 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982 		JBrowse link
G RALBP1 ralA binding protein 1 ISO RGD PMID:23788031 RGD:12904719 NCBI chr 6:98,550,925...98,598,945
Ensembl chr 6:98,550,933...98,598,206 		JBrowse link
positive regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF3 activating transcription factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:130,772,259...130,829,678
Ensembl chr 9:130,772,262...130,785,506 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    cellular process 16838
      signal transduction 6973
        positive regulation of signal transduction 1678
          positive regulation of apoptotic signaling pathway 172
            positive regulation of extrinsic apoptotic signaling pathway + 60
            positive regulation of intrinsic apoptotic signaling pathway + 78
Path 2
Term Annotations click to browse term
  biological_process 17799
    biological regulation 12896
      regulation of biological process 12533
        signaling 7515
          signal transduction 6973
            regulation of signal transduction 3115
              positive regulation of signal transduction 1678
                positive regulation of apoptotic signaling pathway 172
                  positive regulation of extrinsic apoptotic signaling pathway + 60
                  positive regulation of intrinsic apoptotic signaling pathway + 78
paths to the root