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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of apoptotic signaling pathway
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Accession:GO:2001234 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.
Synonyms:exact_synonym: negative regulation of apoptotic signalling pathway


show annotations for term's descendants           Sort by:
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO MGI:1930187 (PMID:17488777) RGD PMID:17488777 NCBI chr10:69,796,502...69,889,671
Ensembl chr10:69,794,007...69,889,634 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
ISS 		(PMID:15946935)
GO_REF:0000024 		RGD
UniProt		 PMID:15946935 GO_REF:0000024 NCBI chr 1:239,278,994...239,386,598
Ensembl chr 1:239,278,994...239,382,024 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2675387 (PMID:18436203) 		Ensembl
RGD		 PMID:18436203 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within 		ISO (PMID:20097879)
(PMID:11546872) 		RGD PMID:11546872 PMID:20097879 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in ISO RNAcentral:URS000055128B_10090 (PMID:26708520) RGD PMID:26708520 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (PMID:11546872) RGD PMID:11546872 NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within
involved_in 		IEA
ISO 		GO_REF:0000107
MGI:99161 (PMID:11290297)
GO_REF:0000117 		Ensembl
RGD
UniProt		 PMID:11290297 GO_REF:0000107 GO_REF:0000117 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:86,243,491...86,250,024 		JBrowse link
G Cdk11b cyclin-dependent kinase 11B acts_upstream_of_or_within ISO MGI:3043373 (PMID:15060143) RGD PMID:15060143 NCBI chr 5:171,495,042...171,521,143
Ensembl chr 5:171,495,776...171,521,145 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:16193064) 		UniProt
RGD		 PMID:16193064 GO_REF:0000024 NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698 		JBrowse link
G Cth cystathionine gamma-lyase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:22244329) 		Ensembl
RGD		 PMID:22244329 GO_REF:0000107 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1858008|MGI:2148567|MGI:98957 (PMID:15131783), (PMID:20454446) 		Ensembl
RGD		 PMID:15131783 PMID:20454446 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IEA 		UniProtKB:P35411 (PMID:10869418)
GO_REF:0000107 		RGD
Ensembl		 PMID:10869418 GO_REF:0000107 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983 		JBrowse link
G Ep300 E1A binding protein p300 IMP cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4888719 (PMID:21209208) 		Ensembl
RGD		 PMID:21209208 GO_REF:0000107 NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:132,512,210...132,538,026 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (PMID:25590961) RGD PMID:25590961 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:117,167,045...117,187,622 		JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 2:198,430,920...198,468,874 JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:23690069 RGD:13792722 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:15731106) 		Ensembl
RGD		 PMID:15731106 GO_REF:0000107 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (PMID:16857185) RGD PMID:16857185 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891 		JBrowse link
G Igbp1 immunoglobulin binding protein 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2448686|MGI:3056510 (PMID:15499020) 		Ensembl
RGD		 PMID:15499020 GO_REF:0000107 NCBI chr  X:69,622,925...69,645,167
Ensembl chr  X:69,622,917...69,646,149 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Ing2 inhibitor of growth family, member 2 acts_upstream_of_or_within ISO MGI:4879096 (PMID:21124965) RGD PMID:21124965 NCBI chr16:51,305,311...51,316,177
Ensembl chr16:51,307,466...51,316,177 		JBrowse link
G LOC134479587 polycomb group RING finger protein 2-like involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 7:764,073...765,186 JBrowse link
G Madd MAP-kinase activating death domain acts_upstream_of_or_within ISO (PMID:14735464) RGD PMID:14735464 NCBI chr 3:97,570,141...97,613,688
Ensembl chr 3:97,570,787...97,613,509 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO MGI:104798 (PMID:16260493) RGD PMID:16260493 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO
IEA 		(PMID:10756100)
GO_REF:0000107 		RGD
Ensembl		 PMID:10756100 GO_REF:0000107 NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:122,406,350...122,416,602 		JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO
IEA 		(PMID:25487955)
GO_REF:0000107 		RGD
Ensembl		 PMID:25487955 GO_REF:0000107 NCBI chr 1:191,060,271...191,065,722
Ensembl chr 1:191,060,280...191,065,339 		JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21059917) 		Ensembl
RGD		 PMID:21059917 GO_REF:0000107 NCBI chr 1:85,986,602...86,000,873
Ensembl chr 1:85,990,050...86,000,873 		JBrowse link
G Mir146a microRNA 146a acts_upstream_of ISO (PMID:28433754) RGD PMID:28433754 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:26780211) RGD PMID:26780211 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:205,755,917...205,756,034 		JBrowse link
G Mnt MAX network transcriptional repressor acts_upstream_of_or_within ISO MGI:2678322 (PMID:12970171) RGD PMID:12970171 NCBI chr10:60,197,654...60,213,221
Ensembl chr10:60,197,948...60,213,209 		JBrowse link
G Mrtfa myocardin related transcription factor A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:12019265) 		Ensembl
RGD		 PMID:12019265 GO_REF:0000107 NCBI chr 7:114,424,481...114,594,594
Ensembl chr 7:114,424,481...114,594,594 		JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of_or_within ISO MGI:2682607|MGI:99702 (PMID:18436203) RGD PMID:18436203 NCBI chr19:40,889,531...40,893,699
Ensembl chr19:40,882,845...40,894,263 		JBrowse link
G Nog noggin acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1862000 (PMID:16712836) 		Ensembl
RGD		 PMID:16712836 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in ISO (PMID:19429166) RGD PMID:19429166 NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769 		JBrowse link
G Pam16 presequence translocase associated motor 16 acts_upstream_of_or_within ISO (PMID:20719856) RGD PMID:20719856 NCBI chr10:11,449,316...11,457,071
Ensembl chr10:11,449,117...11,460,526 		JBrowse link
G Pcgf2 polycomb group ring finger 2 involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000117
MGI:88174 (PMID:11290297) 		UniProt
RGD		 PMID:11290297 GO_REF:0000117 NCBI chr10:83,178,926...83,191,610
Ensembl chr10:83,179,916...83,183,999 		JBrowse link
G Ppef2 protein phosphatase with EF-hand domain 2 involved_in ISO
IEA 		(PMID:20674765)
GO_REF:0000107 		RGD
Ensembl		 PMID:20674765 GO_REF:0000107 NCBI chr14:16,081,706...16,115,903
Ensembl chr14:16,081,706...16,115,903 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:109284 (PMID:15148382) 		Ensembl
RGD		 PMID:15148382 GO_REF:0000107 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (PMID:15148382) RGD PMID:15148382 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116 		JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO
IEA 		(PMID:11096076)
GO_REF:0000107 		RGD
Ensembl		 PMID:11096076 GO_REF:0000107 NCBI chr 8:118,086,243...118,094,274
Ensembl chr 8:118,086,228...118,094,274 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IMP PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA 		(PMID:21075086)
GO_REF:0000033 		RGD
GO_Central		 PMID:21075086 GO_REF:0000033 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO
IEA 		RNAcentral:URS0000330617_9606 (PMID:31124343)
GO_REF:0000107 		RGD
Ensembl		 PMID:31124343 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Wnt16 Wnt family member 16 involved_in ISO
IEA 		(PMID:17200136)
GO_REF:0000107 		RGD
Ensembl		 PMID:17200136 GO_REF:0000107 NCBI chr 4:51,786,728...51,797,137
Ensembl chr 4:51,786,660...51,816,568 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:88276|MGI:96571 (PMID:20454446) 		Ensembl
RGD		 PMID:20454446 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128 		JBrowse link
negative regulation of death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 involved_in IDA PMID:12191471
PMID:15383280 		UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:21785459) RGD PMID:21785459 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS 		(PMID:29507230)
GO_REF:0000024 		RGD
UniProt		 PMID:29507230 GO_REF:0000024 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO
IEA 		(PMID:16940180)
GO_REF:0000107 		RGD
Ensembl		 PMID:16940180 GO_REF:0000107 NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:62,613,638...62,619,500 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO 		PMID:15665855
(PMID:15665855) 		RGD PMID:15665855 PMID:15665855 RGD:1558627 NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:98,408,058...98,449,104 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1341830|MGI:99682 (PMID:22240901) 		Ensembl
RGD		 PMID:22240901 GO_REF:0000107 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IEA
IBA 		(PMID:15102845)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:15102845 GO_REF:0000033 GO_REF:0000107 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:23453807) RGD PMID:23453807 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:157,367,639...157,392,757 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO
IEA 		(PMID:21857923)
GO_REF:0000107 		RGD
Ensembl		 PMID:21857923 GO_REF:0000107 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:124,706,080...124,867,239 		JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:23453807)
GO_REF:0000107
UniProtKB:P58281 (PMID:23453807) 		ParkinsonsUK-UCL
RGD
Ensembl		 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2181360 (PMID:20811152) 		Ensembl
RGD		 PMID:20811152 GO_REF:0000107 NCBI chr12:12,793,957...12,799,156
Ensembl chr12:12,793,957...12,799,156 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:21113145)
GO_REF:0000107
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807) 		ParkinsonsUK-UCL
RGD
Ensembl		 PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21216966) 		Ensembl
RGD		 PMID:21216966 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416 		JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA 		(PMID:17210132)
GO_REF:0000107 		RGD
Ensembl		 PMID:17210132 GO_REF:0000107 NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:129,070,230...129,077,991 		JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:12459480), (PMID:17059562)
MGI:2679656 (PMID:15611074)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:12459480 PMID:15611074 PMID:17059562 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:212,768,907...212,776,457 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within 		ISO (PMID:21075086)
MGI:1913418 (PMID:22240901) 		RGD PMID:21075086 PMID:22240901 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492 		JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within ISO
IEA 		(PMID:18628206)
GO_REF:0000107 		RGD
Ensembl		 PMID:18628206 GO_REF:0000107 NCBI chr 5:128,815,471...128,841,574
Ensembl chr 5:128,815,374...128,841,571 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in IEA
ISO 		GO_REF:0000107
(PMID:16571599) 		Ensembl
RGD		 PMID:16571599 GO_REF:0000107 NCBI chr14:78,035,205...78,059,718
Ensembl chr14:78,034,864...78,060,459 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
IMP 		(PMID:19135031)
GO_REF:0000107
PMID:20625543 		RGD
Ensembl		 PMID:19135031 PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:17116640) 		Ensembl
RGD		 PMID:17116640 GO_REF:0000107 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:O15354 (PMID:17116640), (PMID:23453807) 		Ensembl
RGD		 PMID:17116640 PMID:23453807 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA 		(PMID:9884026)
GO_REF:0000107 		RGD
Ensembl		 PMID:9884026 GO_REF:0000107 NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:63,387,381...63,477,884 		JBrowse link
G Ar androgen receptor acts_upstream_of ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:21310825) 		UniProt
Ensembl
RGD		 PMID:21310825 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 involved_in ISO
IEA 		(PMID:14765125)
GO_REF:0000107 		RGD
Ensembl		 PMID:14765125 GO_REF:0000107 NCBI chr 6:26,474,843...26,668,275
Ensembl chr 6:26,474,843...26,668,507 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15070745) 		Ensembl
RGD		 PMID:15070745 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:22266862), (PMID:9208847)
MGI:109324|MGI:2154952 (PMID:22675671)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:9208847 PMID:22266862 PMID:22675671 GO_REF:0000107 GO_REF:0000117 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434 		JBrowse link
G Cttn cortactin acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1924375 (PMID:22660580) 		Ensembl
RGD		 PMID:22660580 GO_REF:0000107 NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211 		JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (PMID:15734730) RGD PMID:15734730 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888 		JBrowse link
G Fcmr Fc mu receptor acts_upstream_of_or_within ISO (PMID:15632112) RGD PMID:15632112 NCBI chr13:44,889,628...44,903,926
Ensembl chr13:44,889,697...44,906,314 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:104995 (PMID:15288121) 		Ensembl
RGD		 PMID:15288121 GO_REF:0000107 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:104990 (PMID:15288121) 		Ensembl
RGD		 PMID:15288121 GO_REF:0000107 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO
IEA 		(PMID:16636664)
GO_REF:0000107 		RGD
Ensembl		 PMID:16636664 GO_REF:0000107 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Htt huntingtin involved_in IMP
IEA
ISO 		GO_REF:0000107
(PMID:19240112) 		Ensembl
RGD		 PMID:19240112 PMID:17124493 GO_REF:0000107, RGD:6902918 NCBI chr14:80,070,456...80,219,668
Ensembl chr14:80,070,456...80,219,668 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
IDA 		(PMID:16942485)
GO_REF:0000107
PMID:17023532 		RGD
Ensembl		 PMID:16942485 PMID:17023532 GO_REF:0000107, RGD:1600072 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (PMID:23468852) RGD PMID:23468852 NCBI chr13:44,949,989...44,958,714
Ensembl chr13:44,949,989...44,958,714 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Itga6 integrin subunit alpha 6 involved_in ISO (PMID:21310825) RGD PMID:21310825 NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:77,017,766...77,097,076 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO
IEA 		(PMID:10708943)
GO_REF:0000107 		RGD
Ensembl		 PMID:10708943 GO_REF:0000107 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:89,245,095...89,333,511 		JBrowse link
G Lgals3 galectin 3 involved_in ISO
IBA
IEA 		(PMID:22761016)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:22761016 GO_REF:0000033 GO_REF:0000107 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
G Lmna lamin A/C acts_upstream_of_or_within ISO (PMID:21151901) RGD PMID:21151901 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:50,067,978...50,076,715
Ensembl chr19:50,069,015...50,076,709 		JBrowse link
G Mir142 microRNA 142 involved_in ISO UniProtKB:P01137 (PMID:26572508) RGD PMID:26572508 NCBI chr10:73,055,104...73,055,190
Ensembl chr10:73,055,097...73,055,207 		JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:22821565) RGD PMID:22821565 NCBI chr13:77,116,225...77,116,334
Ensembl chr13:77,116,225...77,116,334 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IBA 		(PMID:9560245)
GO_REF:0000033 		RGD
GO_Central		 PMID:9560245 GO_REF:0000033 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Nrp1 neuropilin 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21828096) 		Ensembl
RGD		 PMID:21828096 GO_REF:0000107 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702 		JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 acts_upstream_of_or_within ISO (PMID:12897128) RGD PMID:12897128 NCBI chr 3:143,848,404...144,156,674
Ensembl chr 3:143,849,223...144,156,640 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS 		(PMID:21785459)
GO_REF:0000024 		RGD
ParkinsonsUK-UCL		 PMID:21785459 GO_REF:0000024 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO
IEA 		(PMID:24113711)
MGI:5441750 (PMID:23950925)
GO_REF:0000107 		RGD
Ensembl		 PMID:23950925 PMID:24113711 GO_REF:0000107 NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:211,661,610...211,672,239 		JBrowse link
G Phip pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO
IEA 		(PMID:17636024)
GO_REF:0000107 		RGD
Ensembl		 PMID:17636024 GO_REF:0000107 NCBI chr 8:92,656,890...92,771,098
Ensembl chr 8:92,656,890...92,771,021 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (PMID:15259009) RGD PMID:15259009 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006 		JBrowse link
G Psme3 proteasome activator subunit 3 involved_in ISO (PMID:18309296) RGD PMID:18309296 NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3690329 (PMID:17015619) 		Ensembl
RGD		 PMID:17015619 GO_REF:0000107 NCBI chr 5:17,948,522...18,012,434
Ensembl chr 5:17,948,522...18,012,434 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:21310825)
(PMID:22244329)
GO_REF:0000107 		RGD
Ensembl		 PMID:21310825 PMID:22244329 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:21525013)
MGI:104798|MGI:109200 (PMID:22089168)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:21525013 PMID:22089168 GO_REF:0000107 GO_REF:0000117 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 acts_upstream_of_or_within ISO (PMID:11493700) RGD PMID:11493700 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Scg2 secretogranin II involved_in ISO (PMID:14970115) RGD PMID:14970115 NCBI chr 9:88,251,531...88,257,208
Ensembl chr 9:88,251,354...88,269,598 		JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within ISO (PMID:16226406) RGD PMID:16226406 NCBI chr 1:239,409,991...239,681,195
Ensembl chr 1:239,409,991...239,505,774 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO
IEA 		(PMID:21586138)
GO_REF:0000107 		RGD
Ensembl		 PMID:21586138 GO_REF:0000107 NCBI chr16:33,746,396...33,912,127
Ensembl chr16:33,746,396...33,912,153 		JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in ISO
IEA 		(PMID:21586138)
GO_REF:0000107 		RGD
Ensembl		 PMID:21586138 GO_REF:0000107 NCBI chr 2:145,063,847...145,081,675
Ensembl chr 2:145,063,857...145,081,873 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA 		(PMID:19767770)
GO_REF:0000033 		RGD
GO_Central		 PMID:19767770 GO_REF:0000033 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in IMP PMID:21965303 BHF-UCL PMID:21965303 RGD:14974246 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:264,791,335...264,984,225 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA 		(PMID:18625725)
GO_REF:0000107 		RGD
Ensembl		 PMID:18625725 GO_REF:0000107 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:11009421)
GO_REF:0000117 		Ensembl
RGD
UniProt		 PMID:11009421 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (PMID:11567634) RGD PMID:11567634 NCBI chr 5:171,889,134...171,891,824
Ensembl chr 5:171,889,117...171,892,616 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:21828096) RGD PMID:21828096 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:95484 (PMID:17980593) 		Ensembl
RGD		 PMID:17980593 GO_REF:0000107 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437 		JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:65,226,907...65,323,278
Ensembl chr17:65,234,045...65,323,276 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 7:64,782,618...64,799,624
Ensembl chr 7:64,782,612...64,799,640 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:99702 (PMID:8358790) RGD PMID:8358790 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:84,987,833...84,993,872 		JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2152978 (PMID:9299161) 		Ensembl
RGD		 PMID:9299161 GO_REF:0000107 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO
IEA 		(PMID:10666185)
GO_REF:0000107 		RGD
Ensembl		 PMID:10666185 GO_REF:0000107 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2677796 (PMID:22411810) 		Ensembl
RGD		 PMID:22411810 GO_REF:0000107 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:18322241), (PMID:18971423) 		Ensembl
RGD		 PMID:18322241 PMID:18971423 GO_REF:0000107 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 acts_upstream_of_or_within ISO MGI:2670351 (PMID:18971423) RGD PMID:18971423 NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
MGI:1857803 (PMID:15817220) 		GO_Central
RGD		 PMID:15817220 GO_REF:0000033 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:174,818,554...174,938,034 		JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:150,090,535...150,218,855
Ensembl chr 5:150,137,256...150,218,852 		JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:23,991,431...24,235,132
Ensembl chr 1:23,991,431...24,235,131 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1859647 (PMID:16956603) 		Ensembl
RGD		 PMID:16956603 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (PMID:15070677) RGD PMID:15070677 NCBI chr17:4,487,716...4,490,701
Ensembl chr17:4,484,283...4,497,657 		JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO
IEA 		(PMID:17167422)
GO_REF:0000107 		RGD
Ensembl		 PMID:17167422 GO_REF:0000107 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:17,201,633...17,209,459 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240 		JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within ISO (PMID:16086688) RGD PMID:16086688 NCBI chr 8:85,798,337...85,843,705
Ensembl chr 8:85,798,342...85,843,752 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:8950980) RGD PMID:8950980 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO
IEA 		(PMID:20551324)
GO_REF:0000107 		RGD
Ensembl		 PMID:20551324 GO_REF:0000107 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:72,520,617...72,747,373 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA 		UniProtKB:Q62862 (PMID:20551324)
GO_REF:0000107 		RGD
Ensembl		 PMID:20551324 GO_REF:0000107 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:20921992) RGD PMID:20921992 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849 		JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO (PMID:9115640) RGD PMID:9115640 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:20125124) 		Ensembl
RGD		 PMID:20125124 GO_REF:0000107 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:11050396) 		Ensembl
RGD		 PMID:11050396 GO_REF:0000107 NCBI chr 5:14,128,628...14,255,099
Ensembl chr 5:14,126,257...14,198,331 		JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within
involved_in 		ISO (PMID:10518215) RGD PMID:10518215 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349 		JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:12574163) 		Ensembl
RGD		 PMID:12574163 GO_REF:0000107 NCBI chr 9:67,908,277...67,927,224
Ensembl chr 9:67,908,309...67,927,222 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO
IEA 		(PMID:10449030)
GO_REF:0000107 		RGD
Ensembl		 PMID:10449030 GO_REF:0000107 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA 		(PMID:10666185), (PMID:10748004)
GO_REF:0000107 		RGD
Ensembl		 PMID:10666185 PMID:10748004 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO (PMID:18469807) RGD PMID:18469807 NCBI chr20:29,240,639...29,307,270
Ensembl chr20:29,240,650...29,307,270 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646 		JBrowse link
G Bcl2l1 Bcl2-like 1 acts_upstream_of_or_within ISO (PMID:26582200) RGD PMID:26582200 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO (PMID:23415688) RGD PMID:23415688 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763 		JBrowse link
G Caps calcyphosine acts_upstream_of_or_within ISO (PMID:12466268) RGD PMID:12466268 NCBI chr 9:1,630,871...1,632,758 JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:18202225)
GO_REF:0000107
(PMID:26582200) 		RGD
Ensembl		 PMID:18202225 PMID:26582200 GO_REF:0000107 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434 		JBrowse link
G Dapk1 death associated protein kinase 1 acts_upstream_of_or_within ISO (PMID:11485996) RGD PMID:11485996 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:12,152,346...12,165,983 		JBrowse link
G Faim Fas apoptotic inhibitory molecule involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
(PMID:10075978)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:10075978 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:108,423,259...108,445,365
Ensembl chr 8:108,423,221...108,440,151 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		(PMID:26582200)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:26582200 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:132,512,210...132,538,026 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO
IEA 		(PMID:10903502)
GO_REF:0000107 		RGD
Ensembl		 PMID:10903502 GO_REF:0000107 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12221075) 		Ensembl
RGD		 PMID:12221075 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:18846110) 		UniProt
Ensembl
RGD		 PMID:18846110 GO_REF:0000024 GO_REF:0000107 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:15314156) 		Ensembl
RGD		 PMID:15314156 GO_REF:0000107 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of_or_within ISO MGI:2387671 (PMID:19139395) RGD PMID:19139395 NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO
IEA 		(PMID:18202225)
GO_REF:0000107 		RGD
Ensembl		 PMID:18202225 GO_REF:0000107 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of_or_within ISO MGI:1916885 (PMID:20053891) RGD PMID:20053891 NCBI chr 1:256,704,087...256,727,661
Ensembl chr 1:256,699,832...256,727,644 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:12191471
PMID:15383280 		UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 involved_in ISO
IEA
IBA 		(PMID:10442631)
GO_REF:0000117
GO_REF:0000033
GO_REF:0000107 		RGD
UniProt
GO_Central
Ensembl		 PMID:10442631 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2388026|MGI:95484|MGI:99255 (PMID:16365167) 		Ensembl
RGD		 PMID:16365167 GO_REF:0000107 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISO
IBA
ISS 		(PMID:15069192)
GO_REF:0000033
GO_REF:0000024 		RGD
GO_Central
UniProt		 PMID:15069192 GO_REF:0000024 GO_REF:0000033 NCBI chr10:68,238,273...68,301,225
Ensembl chr10:68,238,273...68,321,902 		JBrowse link
G Rnf34 ring finger protein 34 involved_in ISS
IBA
IEA
ISO 		GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:15069192) 		UniProt
GO_Central
Ensembl
RGD		 PMID:15069192 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:39,364,461...39,385,391
Ensembl chr12:39,355,578...39,385,340 		JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA 		(PMID:18835034)
GO_REF:0000107 		RGD
Ensembl		 PMID:18835034 GO_REF:0000107 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:9391078) 		Ensembl
RGD		 PMID:9391078 GO_REF:0000107 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079 		JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in ISO
IEA 		(PMID:21107705)
GO_REF:0000107 		RGD
Ensembl		 PMID:21107705 GO_REF:0000107 NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:83,320,979...83,338,657 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA 		(PMID:12167698)
GO_REF:0000107 		RGD
Ensembl		 PMID:12167698 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 acts_upstream_of_or_within ISO (PMID:12466268) RGD PMID:12466268 NCBI chr 1:208,269,844...208,285,823
Ensembl chr 1:208,258,836...208,289,832 		JBrowse link
G Ybx3 Y box binding protein 3 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA 		(PMID:21177249)
GO_REF:0000107 		RGD
Ensembl		 PMID:21177249 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA 		(PMID:21177249), (PMID:23261939)
GO_REF:0000107 		RGD
Ensembl		 PMID:21177249 PMID:23261939 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950 		JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003 		JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IDA
IBA
IEA
ISO 		PMID:11231630
GO_REF:0000033
GO_REF:0000107
(PMID:10037731) 		GO_Central
Ensembl
RGD		 PMID:10037731 PMID:11231630 GO_REF:0000033 GO_REF:0000107, RGD:10047348 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997 		JBrowse link
G Kdm6a lysine demethylase 6A IMP RGD PMID:30887465 RGD:151665136 NCBI chr  X:6,920,374...7,060,027
Ensembl chr  X:6,920,343...7,059,960 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP 		PMID:15459207 CAFA PMID:15459207 PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA PMID:10590251 UniProt PMID:10590251 RGD:10047155 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO 		GO_REF:0000107
(PMID:30496354) 		Ensembl
RGD		 PMID:30496354 GO_REF:0000107 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:24553947) 		Ensembl
RGD		 PMID:24553947 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:21075086) RGD PMID:21075086 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:19911006) 		Ensembl
RGD		 PMID:19911006 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO (PMID:11684014) RGD PMID:11684014 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:12011449)
(PMID:21567405) 		RGD PMID:12011449 PMID:21567405 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:84,987,833...84,993,872 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:21883093) RGD PMID:21883093 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:12,152,346...12,165,983 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791 		JBrowse link
G Fignl1 fidgetin-like 1 acts_upstream_of_or_within ISO (PMID:20886204) RGD PMID:20886204 NCBI chr14:90,573,090...90,595,342
Ensembl chr14:90,581,771...90,592,316 		JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3808723 (PMID:18511420) RGD PMID:18511420 NCBI chr 6:74,498,801...74,530,703
Ensembl chr 6:74,503,109...74,528,198 		JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO MGI:1097691 (PMID:21093383) RGD PMID:21093383 NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:108086 (PMID:21093383) RGD PMID:21093383 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311 		JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2178586 (PMID:11325543) 		Ensembl
RGD		 PMID:11325543 GO_REF:0000107 NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:246,114,096...246,159,228 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IEA 		UniProtKB:P37840 (PMID:22045699)
GO_REF:0000107 		RGD
Ensembl		 PMID:22045699 GO_REF:0000107 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081 		JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997 		JBrowse link
G Ivns1abp influenza virus NS1A binding protein acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4820513 (PMID:15485691) 		Ensembl
RGD		 PMID:15485691 GO_REF:0000107 NCBI chr13:65,977,069...65,996,685
Ensembl chr13:65,977,045...65,997,547 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:10098834) 		Ensembl
RGD		 PMID:10098834 GO_REF:0000107 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO 		GO_REF:0000107
(PMID:22984561) 		Ensembl
RGD		 PMID:22984561 GO_REF:0000107 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor involved_in ISO
IEA 		(PMID:16322561)
GO_REF:0000107 		RGD
Ensembl		 PMID:16322561 GO_REF:0000107 NCBI chr 5:172,102,369...172,114,168
Ensembl chr 5:172,101,223...172,114,162 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP
IBA 		PMID:15383280
GO_REF:0000033 		GO_Central PMID:15383280 GO_REF:0000033, RGD:10047289 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in IEA
ISO 		GO_REF:0000107
(PMID:16839884) 		Ensembl
RGD		 PMID:16839884 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO 		GO_REF:0000024
(PMID:16839884) 		ParkinsonsUK-UCL
RGD		 PMID:16839884 GO_REF:0000024 NCBI chr11:94,097,559...94,124,915
Ensembl chr11:94,097,934...94,148,287 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA 		(PMID:15087508)
GO_REF:0000107 		RGD
Ensembl		 PMID:15087508 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950 		JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO
IEA 		(PMID:22984561)
GO_REF:0000107 		RGD
Ensembl		 PMID:22984561 GO_REF:0000107 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISO
ISS 		(PMID:19228691)
GO_REF:0000024 		RGD
UniProt		 PMID:19228691 GO_REF:0000024 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954 		JBrowse link
G Rtkn2 rhotekin 2 involved_in ISO
IEA 		(PMID:26124677)
GO_REF:0000107 		RGD
Ensembl		 PMID:26124677 GO_REF:0000107 NCBI chr20:20,535,553...20,608,863
Ensembl chr20:20,535,553...20,608,899 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA 		(PMID:19767770)
GO_REF:0000033 		RGD
GO_Central		 PMID:19767770 GO_REF:0000033 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:19911006) RGD PMID:19911006 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in ISO
IBA 		(PMID:17936702)
GO_REF:0000033 		RGD
GO_Central		 PMID:17936702 GO_REF:0000033 NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:99,783,158...99,853,906 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO (PMID:12881569) RGD PMID:12881569 NCBI chr15:2,512,214...2,526,105
Ensembl chr15:2,512,216...2,532,229 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr14:78,035,205...78,059,718
Ensembl chr14:78,034,864...78,060,459 		JBrowse link
G Xbp1 X-box binding protein 1 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 involved_in ISO (PMID:17904127) RGD PMID:17904127 NCBI chr 4:14,291,211...14,306,799
Ensembl chr 4:14,291,211...14,306,817 		JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of_or_within ISO MGI:98834 (PMID:26158450) RGD PMID:26158450 NCBI chr 8:112,041,586...112,093,061
Ensembl chr 8:112,041,594...112,084,646 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO
IEA 		(PMID:17805299)
GO_REF:0000107 		RGD
Ensembl		 PMID:17805299 GO_REF:0000107 NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:154,065,543...154,121,775 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO
IEA 		(PMID:17310983)
GO_REF:0000107 		RGD
Ensembl		 PMID:17310983 GO_REF:0000107 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (PMID:12101245) RGD PMID:12101245 NCBI chr13:46,922,236...47,068,241
Ensembl chr13:46,958,298...47,026,372 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:18829576) RGD PMID:18829576 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA 		(PMID:23985028)
GO_REF:0000107 		RGD
Ensembl		 PMID:23985028 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304 		JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,029,608...11,047,395
Ensembl chr20:11,029,608...11,046,909 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2672883 (PMID:12858174) 		Ensembl
RGD		 PMID:12858174 GO_REF:0000107 NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:70,965,590...70,993,670 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3584037 (PMID:15989966) 		Ensembl
RGD		 PMID:15989966 GO_REF:0000107 NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,637,016...2,672,330 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (PMID:24523556) RGD PMID:24523556 NCBI chr 2:236,411,194...236,445,225
Ensembl chr 2:236,410,436...236,445,140 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 involved_in ISO
IEA 		(PMID:20388803)
GO_REF:0000107 		RGD
Ensembl		 PMID:20388803 GO_REF:0000107 NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:15983387) 		Ensembl
RGD		 PMID:15983387 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,568,591...65,616,376 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:16608847) RGD PMID:16608847 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:5428930 (PMID:26219591) 		Ensembl
RGD		 PMID:26219591 GO_REF:0000107 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275 		JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO
IEA 		(PMID:23352644)
GO_REF:0000107 		RGD
Ensembl		 PMID:23352644 GO_REF:0000107 NCBI chr15:51,622,519...51,637,911
Ensembl chr15:51,622,464...51,637,774 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in ISO
IEA 		(PMID:15750620)
GO_REF:0000107 		RGD
Ensembl		 PMID:15750620 GO_REF:0000107 NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:28,108,044...28,110,809 		JBrowse link
G Clu clusterin involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:16113678) 		UniProt
Ensembl
RGD		 PMID:16113678 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO
IEA 		(PMID:20388803)
GO_REF:0000107 		RGD
Ensembl		 PMID:20388803 GO_REF:0000107 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor involved_in ISO
IEA 		(PMID:24214091)
GO_REF:0000107
GO_REF:0000002 		RGD
Ensembl
InterPro		 PMID:24214091 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:156,318,559...156,342,869
Ensembl chr 1:156,318,563...156,342,869 		JBrowse link
G Rnf114 ring finger protein 114 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:176,641,456...176,653,262
Ensembl chr 3:176,641,499...176,671,960 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:14561758) RGD PMID:14561758 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:176,667,476...176,671,965 JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349 		JBrowse link
G Tmem161a transmembrane protein 161A involved_in ISO (PMID:16551573) RGD PMID:16551573 NCBI chr16:19,272,433...19,282,173
Ensembl chr16:19,272,434...19,282,332 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 acts_upstream_of_or_within ISO (PMID:11598139) RGD PMID:11598139 NCBI chr15:57,562,217...57,568,968
Ensembl chr15:57,566,067...57,569,554 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:18632609) RGD PMID:18632609 NCBI chr 5:84,020,604...84,031,483
Ensembl chr 5:84,014,803...84,042,748 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4130032 (PMID:19966869) 		Ensembl
RGD		 PMID:19966869 GO_REF:0000107 NCBI chr 1:175,586,758...175,669,904
Ensembl chr 1:175,586,723...175,669,904 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15983387) 		Ensembl
RGD		 PMID:15983387 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,568,591...65,616,376 		JBrowse link
G Bcl2l12 Bcl2 like 12 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:20837658) 		Ensembl
RGD		 PMID:20837658 GO_REF:0000107 NCBI chr 1:104,608,753...104,617,472
Ensembl chr 1:104,608,753...104,617,472 		JBrowse link
G Cd44 CD44 molecule involved_in ISO
IEA 		(PMID:17045821)
GO_REF:0000107 		RGD
Ensembl		 PMID:17045821 GO_REF:0000107 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cd74 CD74 molecule involved_in ISO
IBA
ISS 		(PMID:17045821)
GO_REF:0000033
GO_REF:0000024 		RGD
GO_Central
BHF-UCL		 PMID:17045821 GO_REF:0000024 GO_REF:0000033 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410 		JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 acts_upstream_of_or_within ISO (PMID:22768269) RGD PMID:22768269 NCBI chr 3:128,866,755...128,870,896
Ensembl chr 3:128,864,777...128,870,852 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO
IEA 		(PMID:17805299)
GO_REF:0000107 		RGD
Ensembl		 PMID:17805299 GO_REF:0000107 NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:154,065,543...154,121,775 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
ISO 		GO_REF:0000024
(PMID:29295817) 		UniProt
RGD		 PMID:29295817 GO_REF:0000024 NCBI chr 3:65,090,640...65,128,768
Ensembl chr 3:65,090,310...65,128,864 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821) RGD PMID:17045821 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:11672522) 		Ensembl
RGD		 PMID:11672522 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO
IEA 		(PMID:15735003)
GO_REF:0000107 		RGD
Ensembl		 PMID:15735003 GO_REF:0000107 NCBI chr12:46,928,273...46,930,766
Ensembl chr12:46,928,273...46,930,766 		JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO
IEA 		(PMID:17719541)
GO_REF:0000107 		RGD
Ensembl		 PMID:17719541 GO_REF:0000107 NCBI chr 7:136,327,393...136,354,017
Ensembl chr 7:136,327,393...136,354,321 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca3 carbonic anhydrase 3 IMP RGD PMID:29559661 RGD:408427357 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 acts_upstream_of_or_within ISO (PMID:18681888) RGD PMID:18681888 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:24947010) RGD PMID:24947010 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA
IMP 		(PMID:17579517)
GO_REF:0000107 		RGD
Ensembl		 PMID:17579517 PMID:17579517 GO_REF:0000107, RGD:8693356 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q99497 (PMID:24947010) 		Ensembl
RGD		 PMID:24947010 GO_REF:0000107 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948 		JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,971,259...12,005,306
Ensembl chr10:11,970,995...12,005,355 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646 		JBrowse link
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857135 (PMID:16571598) 		Ensembl
RGD		 PMID:16571598 GO_REF:0000107 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209 		JBrowse link
G Epo erythropoietin involved_in ISO
IEA 		(PMID:14569084)
GO_REF:0000107 		RGD
Ensembl		 PMID:14569084 GO_REF:0000107 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725 		JBrowse link
G Ptger2 prostaglandin E receptor 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr15:20,694,765...20,708,475
Ensembl chr15:20,696,013...20,708,950 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ybx3 Y box binding protein 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:22711822) 		Ensembl
RGD		 PMID:22711822 GO_REF:0000107 NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:98834|MGI:99702 (PMID:16571598) 		Ensembl
RGD		 PMID:16571598 GO_REF:0000107 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209 		JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISS
ISO 		GO_REF:0000107
GO_REF:0000024
(PMID:18371312) 		Ensembl
UniProt
RGD		 PMID:18371312 GO_REF:0000024 GO_REF:0000107 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:15901672), (PMID:9393856)
GO_REF:0000114 		RGD
ComplexPortal		 PMID:9393856 PMID:15901672 GO_REF:0000114 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IEA
ISO 		GO_REF:0000107
(PMID:27098698) 		Ensembl
RGD		 PMID:27098698 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21370995) 		Ensembl
RGD		 PMID:21370995 GO_REF:0000107 NCBI chr 3:128,783,408...128,789,485
Ensembl chr 3:128,783,597...128,789,483 		JBrowse link
G ENSRNOG00000063076 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:104995 (PMID:15288121) 		Ensembl
RGD		 PMID:15288121 GO_REF:0000107 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:19096392) 		Ensembl
RGD		 PMID:19096392 GO_REF:0000107 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377 		JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:2,495,605...2,532,448
Ensembl chr10:2,495,607...2,532,448 		JBrowse link
G Slc25a31 solute carrier family 25 member 31 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:125,623,331...125,639,155
Ensembl chr 2:125,623,341...125,654,376 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:52,805,523...52,811,700 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
IBA
ISO 		GO_REF:0000024
GO_REF:0000033
(PMID:19154410) 		UniProt
GO_Central
RGD		 PMID:19154410 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:120,897,616...120,900,683
Ensembl chr  X:120,897,563...120,900,688 		JBrowse link
G Slc35f6 solute carrier family 35, member F6 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:19154410) 		UniProt
Ensembl
RGD		 PMID:19154410 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:31,445,738...31,457,580
Ensembl chr 6:31,445,742...31,457,608 		JBrowse link
G Tmem14a transmembrane protein 14A involved_in ISO (PMID:21723035) RGD PMID:21723035 NCBI chr 9:31,137,011...31,148,794
Ensembl chr 9:31,136,963...31,148,800 		JBrowse link
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:136,589,623...136,593,278
Ensembl chr 6:136,584,741...136,598,492 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of ISO (PMID:25590961) RGD PMID:25590961 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2158814 (PMID:16373599) 		Ensembl
RGD		 PMID:16373599 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15731106) 		Ensembl
RGD		 PMID:15731106 GO_REF:0000107 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA 		(PMID:23043106)
GO_REF:0000107 		RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806 		JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:50,067,978...50,076,715
Ensembl chr19:50,069,015...50,076,709 		JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr 4:60,618,334...60,618,414 JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr13:109,098,831...109,098,911
Ensembl chr13:109,098,827...109,098,916 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO
IEA 		(PMID:23043106)
GO_REF:0000107 		RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nme5 NME/NM23 family member 5 involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:12788088) 		GO_Central
RGD		 PMID:12788088 GO_REF:0000033 NCBI chr18:26,437,705...26,454,828
Ensembl chr18:26,437,781...26,454,828 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO (PMID:15004034) RGD PMID:15004034 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of ISO (PMID:22523093) RGD PMID:22523093 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS 		(PMID:26095851)
GO_REF:0000024 		RGD
UniProt		 PMID:26095851 GO_REF:0000024 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,361,379...21,362,147 JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA 		(PMID:17317627)
GO_REF:0000107 		RGD
Ensembl		 PMID:17317627 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO
IEA 		(PMID:12551919)
GO_REF:0000107 		RGD
Ensembl		 PMID:12551919 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07001519.1 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117
G Atf4 activating transcription factor 4 involved_in IMP
IEA
ISO 		PMID:23392669
GO_REF:0000107
UniProtKB:Q9ES19 (PMID:23392669) 		Ensembl
RGD		 PMID:23392669 PMID:23392669 GO_REF:0000107, RGD:10047168 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Cpe carboxypeptidase E IMP RGD PMID:25426952 RGD:405650601 NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21752258) 		Ensembl
RGD		 PMID:21752258 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of
involved_in 		ISO
IEA 		(PMID:26310625)
GO_REF:0000107
(PMID:25029497) 		RGD
Ensembl		 PMID:25029497 PMID:26310625 GO_REF:0000107 NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:19,696,961...19,725,180 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:25426952 RGD:405650601 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fzd1 frizzled class receptor 1 involved_in ISO (PMID:21752258) RGD PMID:21752258 NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA 		(PMID:24899725)
GO_REF:0000107 		RGD
Ensembl		 PMID:24899725 GO_REF:0000107 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Il10 interleukin 10 involved_in IEA
ISO 		GO_REF:0000107
ComplexPortal:CPX-1134 (PMID:21857966) 		Ensembl
RGD		 PMID:21857966 GO_REF:0000107 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO
IEA 		(PMID:15790595)
GO_REF:0000107 		RGD
Ensembl		 PMID:15790595 GO_REF:0000107 NCBI chr  X:70,594,116...70,611,976
Ensembl chr  X:70,593,888...70,611,979 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO 		GO_REF:0000024
(PMID:24899725)
(PMID:15790595), (PMID:16632486), (PMID:23743200) 		ParkinsonsUK-UCL
RGD		 PMID:15790595 PMID:16632486 PMID:23743200 PMID:24899725 GO_REF:0000024 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA 		(PMID:16632486)
GO_REF:0000107 		RGD
Ensembl		 PMID:16632486 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
IGI
ISS 		(PMID:17314283)
(PMID:23858059)
GO_REF:0000117
GO_REF:0000107
PMID:23392669
GO_REF:0000024 		RGD
UniProt
Ensembl
ParkinsonsUK-UCL		 PMID:17314283 PMID:23858059 PMID:23392669 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117, RGD:10047168 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:106,416,056...106,420,982
Ensembl chr10:106,412,576...106,423,393 		JBrowse link
G Wnt1 Wnt family member 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21752258) 		Ensembl
RGD		 PMID:21752258 GO_REF:0000107 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:131,817,558...131,821,605 		JBrowse link
negative regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:18977203)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:18977203 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:15901672), (PMID:9393856)
GO_REF:0000114 		RGD
ComplexPortal		 PMID:9393856 PMID:15901672 GO_REF:0000114 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl2l2 Bcl2-like 2 IDA RGD PMID:10724126 RGD:14394498 NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379 		JBrowse link
G Fxn frataxin involved_in ISO (PMID:16608849) RGD PMID:16608849 NCBI chr 1:231,300,457...231,323,989
Ensembl chr 1:231,300,150...231,323,989 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein involved_in ISO (PMID:18417609) RGD PMID:18417609 NCBI chr16:12,907,062...12,918,149
Ensembl chr16:12,905,806...12,918,123 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA 		(PMID:12221075)
GO_REF:0000107 		RGD
Ensembl		 PMID:12221075 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Hgf hepatocyte growth factor involved_in ISO
IEA 		(PMID:20655899)
GO_REF:0000107 		RGD
Ensembl		 PMID:20655899 GO_REF:0000107 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21856340) 		Ensembl
RGD		 PMID:21856340 GO_REF:0000107 NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:130,391,661...130,400,888 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in IMP
IEA 		GO_REF:0000117 UniProt
RGD		 PMID:16397188 GO_REF:0000117, RGD:1626654 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspa8-ps23 heat shock protein family A (Hsp70) member 8, pseudogene 23 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  X:36,166,923...36,170,616
Ensembl chr  X:36,166,178...36,169,273 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:18977203) 		UniProt
RGD		 PMID:18977203 GO_REF:0000024 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Lmna lamin A/C acts_upstream_of_or_within ISO (PMID:21151901) RGD PMID:21151901 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:50,067,978...50,076,715
Ensembl chr19:50,069,015...50,076,709 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:18006463 RGD:12738362 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IBA
ISO 		PMID:10590251
GO_REF:0000033
(PMID:15004034) 		GO_Central
RGD		 PMID:15004034 PMID:10590251 GO_REF:0000033, RGD:10047155 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:16839884)
GO_REF:0000107
(PMID:21149567) 		ParkinsonsUK-UCL
RGD
Ensembl		 PMID:16839884 PMID:21149567 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955 		JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:11,449,316...11,457,071
Ensembl chr10:11,449,117...11,460,526 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO 		GO_REF:0000024
(PMID:16839884) 		ParkinsonsUK-UCL
RGD		 PMID:16839884 GO_REF:0000024 NCBI chr11:94,097,559...94,124,915
Ensembl chr11:94,097,934...94,148,287 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO 		GO_REF:0000024
(PMID:19228691) 		UniProt
RGD		 PMID:19228691 GO_REF:0000024 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954 		JBrowse link
G Prelid1 PRELI domain containing 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr17:9,310,471...9,313,511
Ensembl chr17:9,310,472...9,313,531 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS 		(PMID:19880420), (PMID:23453807)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
ParkinsonsUK-UCL		 PMID:19880420 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
IEA
ISS 		(PMID:19729910)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:19729910 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:109,445,291...109,453,605
Ensembl chr  X:109,445,291...109,453,605 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO
IEA 		(PMID:23931759)
GO_REF:0000107 		RGD
Ensembl		 PMID:23931759 GO_REF:0000107 NCBI chr12:46,928,273...46,930,766
Ensembl chr12:46,928,273...46,930,766 		JBrowse link
negative regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir221 microRNA 221 involved_in ISO (PMID:18246122) RGD PMID:18246122 NCBI chr  X:6,023,182...6,023,290
Ensembl chr  X:6,023,182...6,023,290 		JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:18246122) RGD PMID:18246122 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:6,022,621...6,022,723 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO 		GO_REF:0000024
(PMID:21785459) 		ParkinsonsUK-UCL
RGD		 PMID:21785459 GO_REF:0000024 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      signal transduction 7098
        negative regulation of signal transduction 1591
          negative regulation of apoptotic signaling pathway 275
            negative regulation of apoptosome assembly 0
            negative regulation of extrinsic apoptotic signaling pathway + 110
            negative regulation of intrinsic apoptotic signaling pathway + 124
            negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 16
            negative regulation of release of cytochrome c from mitochondria 27
Path 2
Term Annotations click to browse term
  biological_process 19315
    biological regulation 13355
      regulation of biological process 12936
        signaling 7667
          signal transduction 7098
            regulation of signal transduction 3327
              negative regulation of signal transduction 1591
                negative regulation of apoptotic signaling pathway 275
                  negative regulation of apoptosome assembly 0
                  negative regulation of extrinsic apoptotic signaling pathway + 110
                  negative regulation of intrinsic apoptotic signaling pathway + 124
                  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 16
                  negative regulation of release of cytochrome c from mitochondria 27
paths to the root