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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of CD8-positive, alpha-beta T cell activation
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Accession:GO:2001185 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.


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regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRTAM cytotoxic and regulatory T cell molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:11,458,360...11,485,469
Ensembl chr 5:11,458,008...11,485,448 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) UniProt PMID:28813410 PMID:28813417 NCBI chr 1:93,461,735...93,605,772
Ensembl chr 1:93,585,518...93,603,522 		JBrowse link
G DAPL1 death associated protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:4,678,544...4,698,711
Ensembl chr36:4,678,563...4,698,710 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC4A2 solute carrier family 4 member 2 involved_in ISO (MGI:6840447|PMID:24515893) UniProt PMID:24515893 MGI:6840447 NCBI chr16:15,111,078...15,126,618
Ensembl chr16:15,111,116...15,126,617 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in ISO (MGI:6140589|PMID:24880459) UniProt PMID:24880459 MGI:6140589 NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC4A2 solute carrier family 4 member 2 involved_in ISO (MGI:6840447|PMID:24515893) UniProt PMID:24515893 MGI:6840447 NCBI chr16:15,111,078...15,126,618
Ensembl chr16:15,111,116...15,126,617 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687 		JBrowse link
positive regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLA-12 MHC class I DLA-12 involved_in ISO (PMID:28676677) UniProt PMID:28676677 NCBI chr12:933,321...936,671
Ensembl chr12:932,613...987,561 		JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFB core-binding factor subunit beta involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168 		JBrowse link
G LOC484306 leukocyte immunoglobulin-like receptor subfamily B member 3 involved_in ISO (PMID:18420485) ARUK-UCL PMID:18420485 NCBI chr 1:102,779,562...102,786,924 JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439 		JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G RUNX3 RUNX family transcription factor 3 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948
positive regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD244 CD244 molecule involved_in ISO (MGI:5700312|PMID:11739483) UniProt PMID:11739483 MGI:5700312 NCBI chr38:21,495,649...21,522,656
Ensembl chr38:21,495,720...21,517,043 		JBrowse link
G DLA-12 MHC class I DLA-12 involved_in ISO (PMID:25631937) UniProt PMID:25631937 NCBI chr12:933,321...936,671
Ensembl chr12:932,613...987,561 		JBrowse link
G LOC490356 lymphotactin involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chr 7:29,986,433...29,991,096 JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:51,623,628...51,683,039
Ensembl chr17:51,623,623...51,682,858 		JBrowse link
regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZBTB7B zinc finger and BTB domain containing 7B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18776904) Ensembl
MGI		 PMID:18776904 GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF1 interferon regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608 		JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:43,517,186...43,522,603
Ensembl chr18:43,517,677...43,526,379 		JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in ISO (MGI:5546548|PMID:23963642) UniProt PMID:23963642 MGI:5546548 NCBI chr25:20,025,920...20,208,470
Ensembl chr25:20,015,915...20,205,946 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    immune system process 2495
      leukocyte activation 1025
        lymphocyte activation 833
          T cell activation 588
            alpha-beta T cell activation 198
              regulation of alpha-beta T cell activation 123
                regulation of CD8-positive, alpha-beta T cell activation 20
                  negative regulation of CD8-positive, alpha-beta T cell activation + 7
                  positive regulation of CD8-positive, alpha-beta T cell activation + 9
                  regulation of CD8-positive, alpha-beta T cell differentiation + 8
                  regulation of CD8-positive, alpha-beta T cell proliferation + 9
Path 2
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of biological process 12078
        regulation of cellular process 11571
          regulation of cell activation 641
            regulation of leukocyte activation 587
              regulation of lymphocyte activation 509
                regulation of T cell activation 371
                  regulation of alpha-beta T cell activation 123
                    regulation of CD8-positive, alpha-beta T cell activation 20
                      negative regulation of CD8-positive, alpha-beta T cell activation + 7
                      positive regulation of CD8-positive, alpha-beta T cell activation + 9
                      regulation of CD8-positive, alpha-beta T cell differentiation + 8
                      regulation of CD8-positive, alpha-beta T cell proliferation + 9
paths to the root