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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of double-strand break repair
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Accession:GO:2000781 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of double-strand break repair.


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positive regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX11 DEAD/H-box helicase 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,359,399...67,395,739
Ensembl chr 5:67,364,877...67,395,730 		JBrowse link
G FMN2 formin 2 involved_in ISO (PMID:26287480) UniProt PMID:26287480
G FOXM1 forkhead box M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,246,219...67,263,215
Ensembl chr 5:67,245,694...67,263,211
Ensembl chr 5:67,245,694...67,263,211 		JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (MGI:6467697|PMID:29125140), (MGI:6716977|PMID:33115731) UniProt PMID:29125140 PMID:33115731 MGI:6467697 MGI:6716977 NCBI chr 1:52,996,706...52,999,074 JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase involved_in ISO (PMID:24147153) BHF-UCL PMID:24147153 NCBI chr14:138,502,005...138,771,543
Ensembl chr14:138,499,309...138,771,540 		JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6467697|PMID:29125140) UniProt PMID:29125140 MGI:6467697 NCBI chr 1:53,006,898...53,007,877
Ensembl chr 1:53,006,761...53,007,877 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,568,539...74,577,774
Ensembl chr 2:74,568,493...74,577,772 		JBrowse link
G SLF1 SMC5-SMC6 complex localization factor 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:101,286,744...101,375,612
Ensembl chr 2:101,313,091...101,375,607 		JBrowse link
G SLF2 SMC5-SMC6 complex localization factor 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr14:111,996,781...112,049,309
Ensembl chr14:111,996,783...112,047,885 		JBrowse link
G SPIDR scaffold protein involved in DNA repair involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,874,937...80,190,744
Ensembl chr 4:79,874,831...80,190,655 		JBrowse link
G SPIRE1 spire type actin nucleation factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:96,934,023...97,114,591
Ensembl chr 6:96,934,227...97,114,587 		JBrowse link
G SPIRE2 spire type actin nucleation factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:211,480...246,109
Ensembl chr 6:211,487...243,561 		JBrowse link
G TIMELESS timeless circadian regulator involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:21,763,014...21,787,521 JBrowse link
G UBE2N ubiquitin conjugating enzyme E2 N involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:89,673,306...89,716,345
Ensembl chr 5:89,673,573...89,714,281 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,621,343...79,652,502
Ensembl chr 4:79,621,349...79,652,471 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,954,674...52,968,371
Ensembl chr12:52,954,669...52,968,364 		JBrowse link
G ZCWPW1 zinc finger CW-type and PWWP domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,318,683...8,356,195
Ensembl chr 3:8,323,191...8,358,487 		JBrowse link
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTB actin beta involved_in ISO (PMID:27153538) ComplexPortal PMID:27153538 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356 		JBrowse link
G ACTL6A actin like 6A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:117,598,415...117,627,311
Ensembl chr13:117,598,496...117,628,488 		JBrowse link
G ACTR2 actin related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:76,691,275...76,729,269
Ensembl chr 3:76,691,280...76,729,252 		JBrowse link
G ARID2 AT-rich interaction domain 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,637,385...76,800,155
Ensembl chr 5:76,636,967...76,797,043 		JBrowse link
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:25520194) MGI PMID:25520194 NCBI chr 7:53,317,515...53,412,649
Ensembl chr 7:53,317,540...53,412,645 		JBrowse link
G BRD8 bromodomain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:140,182,195...140,202,247
Ensembl chr 2:140,168,636...140,202,247 		JBrowse link
G CREBBP CREB binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,224 		JBrowse link
G DMAP1 DNA methyltransferase 1 associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:167,083,053...167,091,654
Ensembl chr 6:167,082,849...167,091,630 		JBrowse link
G EP400 E1A binding protein p400 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:23,286,938...23,396,316
Ensembl chr14:23,289,244...23,396,656 		JBrowse link
G EPC1 enhancer of polycomb homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:42,835,280...42,946,859
Ensembl chr10:42,836,047...42,946,857 		JBrowse link
G EPC2 enhancer of polycomb homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:3,417,446...3,526,223
Ensembl chr15:3,417,063...3,526,171 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) UniProt PMID:25820262 NCBI chr14:89,998,125...90,075,911
Ensembl chr14:90,002,024...90,075,898 		JBrowse link
G FANCB FA complementation group B involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 (PMID:25520194) GO_Central
MGI
TreeGrafter		 PMID:25520194 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:11,386,360...11,408,958
Ensembl chr  X:11,384,912...11,409,057 		JBrowse link
G FUS FUS RNA binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,314,936...17,326,663
Ensembl chr 3:17,314,332...17,326,637 		JBrowse link
G HDGFL2 HDGF like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,331,891...74,357,037
Ensembl chr 2:74,332,106...74,357,040 		JBrowse link
G HELQ helicase, POLQ like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:135,026,117...135,061,051
Ensembl chr 8:135,026,315...135,061,043 		JBrowse link
G ING3 inhibitor of growth family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:25,946,529...25,976,528
Ensembl chr18:25,948,097...25,976,499 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,560,544...6,572,461
Ensembl chr 2:6,560,513...6,572,466 		JBrowse link
G KHDC3L KH domain containing 3 like, subcortical maternal complex member involved_in ISO (PMID:31609975)
(MGI:6716962|PMID:25936915)		 UniProt PMID:25936915 PMID:31609975 MGI:6716962 NCBI chr 1:52,996,706...52,999,074 JBrowse link
G MBTD1 mbt domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:27,450,809...27,526,412
Ensembl chr12:27,450,806...27,526,194 		JBrowse link
G MEAF6 MYST/Esa1 associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:93,559,259...93,589,030
Ensembl chr 6:93,559,101...93,589,001 		JBrowse link
G MORF4L1 mortality factor 4 like 1 involved_in ISO (PMID:27153538) ComplexPortal PMID:27153538 NCBI chr 7:48,050,050...48,075,799
Ensembl chr 7:48,050,045...48,075,795 		JBrowse link
G MORF4L2 mortality factor 4 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:84,553,770...84,566,304
Ensembl chr  X:84,553,774...84,569,030 		JBrowse link
G MRGBP MRG domain binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:62,058,401...62,062,962
Ensembl chr17:62,058,424...62,062,960 		JBrowse link
G MRNIP MRN complex interacting protein involved_in ISO (PMID:27568553) UniProt PMID:27568553 NCBI chr 2:78,730,611...78,753,152 JBrowse link
G OOEP oocyte expressed protein involved_in ISO (MGI:6272426|PMID:29955025) UniProt PMID:29955025 MGI:6272426 NCBI chr 1:53,006,898...53,007,877
Ensembl chr 1:53,006,761...53,007,877 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:77,740,460...77,796,911
Ensembl chr 3:77,713,489...77,796,914 		JBrowse link
G PIAS4 protein inhibitor of activated STAT 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,702,915...74,729,792
Ensembl chr 2:74,702,945...74,729,775 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,718,845...54,730,411
Ensembl chr 6:54,714,157...54,732,574 		JBrowse link
G RAD51AP1 RAD51 associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:65,872,277...65,897,210
Ensembl chr 5:65,872,539...65,897,212 		JBrowse link
G RNF126 ring finger protein 126 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,673,302...77,683,312
Ensembl chr 2:77,673,353...77,683,311 		JBrowse link
G RNF8 ring finger protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:32,931,786...32,969,536
Ensembl chr 7:32,931,786...32,970,585 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:72,196,219...72,246,514
Ensembl chr13:72,200,511...72,248,582 		JBrowse link
G RUVBL2 RuvB like AAA ATPase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,250,494...54,263,492
Ensembl chr 6:54,250,515...54,266,893 		JBrowse link
G SKP2 S-phase kinase associated protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:21,463,270...21,500,925
Ensembl chr16:21,463,012...21,509,310 		JBrowse link
G TIMELESS timeless circadian regulator involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:21,763,014...21,787,521 JBrowse link
G TRRAP transformation/transcription domain associated protein involved_in ISO (PMID:27153538) ComplexPortal PMID:27153538 NCBI chr 3:5,903,205...6,029,343
Ensembl chr 3:5,909,022...6,029,333 		JBrowse link
G VPS72 vacuolar protein sorting 72 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,062,261...98,074,074
Ensembl chr 4:98,062,256...98,074,059 		JBrowse link
G WAS WASP actin nucleation promoting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,774,597...42,793,055
Ensembl chr  X:42,774,588...42,793,055 		JBrowse link
G WDR48 WD repeat domain 48 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,735,566...23,786,312
Ensembl chr13:23,735,567...23,786,308 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,954,674...52,968,371
Ensembl chr12:52,954,669...52,968,364 		JBrowse link
G YEATS4 YEATS domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:33,626,816...33,649,633
Ensembl chr 5:33,626,818...33,649,627 		JBrowse link
positive regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FH fumarate hydratase involved_in ISS UniProt GO_REF:0000024 NCBI chr10:12,404,143...12,431,843
Ensembl chr10:12,404,176...12,431,824 		JBrowse link
G KMT5B lysine methyltransferase 5B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:4,710,510...4,768,237
Ensembl chr 2:4,711,023...4,765,979 		JBrowse link
G KMT5C lysine methyltransferase 5C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:59,517,058...59,524,551
Ensembl chr 6:59,517,098...59,524,550 		JBrowse link
G LOC100514009 histone-lysine N-methyltransferase SETMAR involved_in ISO (PMID:20620605), (PMID:21491884) UniProt PMID:20620605 PMID:21491884 NCBI chr13:60,914,412...60,933,064 JBrowse link
G LOC100627380 lysine-specific demethylase 4D-like acts_upstream_of_or_within ISO (PMID:24550317) MGI PMID:24550317 NCBI chr 9:27,083,348...27,085,693 JBrowse link
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,773,680...71,779,192
Ensembl chr 6:71,773,682...71,779,183 		JBrowse link
G PARP3 poly(ADP-ribose) polymerase family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:34,075,807...34,084,384
Ensembl chr13:34,076,012...34,085,210 		JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,870,359...54,880,814
Ensembl chr 6:54,867,637...54,881,088 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656 		JBrowse link
G RIF1 replication timing regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:769,518...832,036
Ensembl chr15:774,191...832,010 		JBrowse link
G SHLD1 shieldin complex subunit 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr17:14,610,723...14,706,082
Ensembl chr17:14,610,817...14,707,872 		JBrowse link
G SHLD2 shieldin complex subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,005,599...88,121,155
Ensembl chr14:88,005,611...88,121,352 		JBrowse link
G SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:103,809,732...103,986,057
Ensembl chr 6:103,808,066...103,965,335 		JBrowse link
G TOP2B DNA topoisomerase II beta ISO RGD PMID:22019940 RGD:13432143 NCBI chr13:12,507,738...12,575,042
Ensembl chr13:12,507,138...12,575,583 		JBrowse link
G TRAPPC13 trafficking protein particle complex subunit 13 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:44,146,574...44,186,346
Ensembl chr16:44,156,163...44,184,662 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,954,674...52,968,371
Ensembl chr12:52,954,669...52,968,364 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    positive regulation of biological process 6500
      positive regulation of response to stimulus 2401
        positive regulation of DNA repair 118
          positive regulation of double-strand break repair 72
            positive regulation of double-strand break repair via homologous recombination 43
            positive regulation of double-strand break repair via nonhomologous end joining 16
Path 2
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      organic substance metabolic process 9930
        organic cyclic compound metabolic process 5601
          nucleobase-containing compound metabolic process 5148
            nucleic acid metabolic process 4652
              DNA metabolic process 926
                regulation of DNA metabolic process 467
                  positive regulation of DNA metabolic process 291
                    positive regulation of DNA repair 118
                      positive regulation of double-strand break repair 72
                        positive regulation of double-strand break repair via homologous recombination 43
                        positive regulation of double-strand break repair via nonhomologous end joining 16
paths to the root