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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cellular senescence
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Accession:GO:2000773 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.



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negative regulation of cellular senescence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:104738 (MGI:5449665|PMID:22729085) RGD PMID:22729085 MGI:5449665 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Akt3 AKT serine/threonine kinase 3 involved_in ISO
IEA
(PMID:25323119)
GO_REF:0000107
RGD
Ensembl
PMID:25323119 GO_REF:0000107 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Bcl2l12 Bcl2-like 12 acts_upstream_of_or_within ISO (MGI:4834958|PMID:20837658) RGD PMID:20837658 MGI:4834958 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (MGI:5469797|PMID:23209284) RGD PMID:23209284 MGI:5469797 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:17420273) RGD PMID:17420273 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO
IEA
(MGI:5009768|PMID:21241890)
GO_REF:0000107
RGD
Ensembl
PMID:21241890 GO_REF:0000107 MGI:5009768 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO (MGI:5582375|PMID:23072816) RGD PMID:23072816 MGI:5582375 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G LOC100912427 nuclease-sensitive element-binding protein 1-like involved_in ISO (MGI:6158172|PMID:29712925) RGD PMID:29712925 MGI:6158172 NCBI chr 1:171,304,587...171,306,092
Ensembl chr 1:171,304,774...171,306,097
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 involved_in ISO (PMID:28640956) RGD PMID:28640956 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:10562313) RGD PMID:10562313 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IDA RGD PMID:28125705 RGD:13781884 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Plk2 polo-like kinase 2 involved_in ISO (MGI:6120300|PMID:27908889) RGD PMID:27908889 MGI:6120300 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:22981234 RGD:8696027 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:5009768|PMID:21241890) RGD PMID:21241890 MGI:5009768 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 involved_in ISO
IEA
(PMID:28595801)
GO_REF:0000107
RGD
Ensembl
PMID:28595801 GO_REF:0000107 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:20203304), (PMID:20424141) RGD PMID:20203304 PMID:20424141 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:22753495), (PMID:27043296), (PMID:29474172) RGD PMID:22753495 PMID:27043296 PMID:29474172 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Slc30a10 solute carrier family 30, member 10 involved_in ISO (PMID:22427991) RGD PMID:22427991 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103
JBrowse link
G Tbx2 T-box transcription factor 2 involved_in ISO (PMID:11062467), (PMID:12000749) RGD PMID:11062467 PMID:12000749 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
G Terc telomerase RNA component involved_in ISO (PMID:11313459) RGD PMID:11313459 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11927518) RGD PMID:11927518 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:11313459), (PMID:11927518) RGD PMID:11313459 PMID:11927518 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tp63 tumor protein p63 involved_in ISO (PMID:19451233) RGD PMID:19451233 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO
IEA
(PMID:16501043)
GO_REF:0000107
RGD
Ensembl
PMID:16501043 GO_REF:0000107 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Ybx1 Y box binding protein 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6158172|PMID:29712925)
UniProt
Ensembl
RGD
PMID:29712925 GO_REF:0000024 GO_REF:0000107 MGI:6158172 NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 involved_in ISO (PMID:23434374) RGD PMID:23434374 NCBI chr17:43,217,168...43,232,828
Ensembl chr17:43,217,222...43,232,827
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular metabolic process 9697
        negative regulation of cellular metabolic process 2376
          negative regulation of cellular senescence 28
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        negative regulation of biological process 5769
          negative regulation of metabolic process 3297
            negative regulation of cellular metabolic process 2376
              negative regulation of cellular senescence 28
paths to the root