ONTOLOGY REPORT - ANNOTATIONS |
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Term: | regulation of cellular senescence |
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Accession: | GO:2000772
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browse the term
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Definition: | Any process that modulates the frequency, rate or extent of cellular senescence. |
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Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
acts_upstream_of_or_within |
ISO |
MGI:1338938 (PMID:22729085) |
RGD |
PMID:22729085 |
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NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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Bmal1 |
basic helix-loop-helix ARNT like 1 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:22101268) |
UniProt RGD |
PMID:22101268 |
GO_REF:0000024 |
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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Bmpr1a |
bone morphogenetic protein receptor type 1A |
acts_upstream_of_or_within |
ISO |
MGI:87859 (PMID:22729085) |
RGD |
PMID:22729085 |
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NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
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Icmt |
isoprenylcysteine carboxyl methyltransferase |
acts_upstream_of_or_within |
ISO |
MGI:1890508 (PMID:23686339) |
RGD |
PMID:23686339 |
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NCBI chr 5:162,804,368...162,811,129
Ensembl chr 5:162,804,368...162,811,128
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Nek4 |
NIMA-related kinase 4 |
involved_in |
ISO |
(PMID:22851694) |
RGD |
PMID:22851694 |
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NCBI chr16:6,144,900...6,185,376
Ensembl chr16:6,144,959...6,188,932
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Nuak1 |
NUAK family kinase 1 |
involved_in |
ISO |
(PMID:19927127) |
RGD |
PMID:19927127 |
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NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913
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Pnpt1 |
polyribonucleotide nucleotidyltransferase 1 |
involved_in |
ISO |
(PMID:16055741) |
RGD |
PMID:16055741 |
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NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696
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Rsl1d1 |
ribosomal L1 domain containing 1 |
involved_in |
ISO |
(PMID:18678645) |
RGD |
PMID:18678645 |
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NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
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Suv39h1 |
SUV39H1 histone lysine methyltransferase |
acts_upstream_of_or_within |
ISO |
MGI:2445449 (PMID:23695662) |
RGD |
PMID:23695662 |
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NCBI chr X:14,421,028...14,433,993
Ensembl chr X:14,421,109...14,433,982
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Suv39h1-ps1 |
SUV39H1 histone lysine methyltransferase, pseudogene 1 |
acts_upstream_of_or_within |
ISO |
MGI:2445449 (PMID:23695662) |
RGD |
PMID:23695662 |
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NCBI chr X:141,792,589...141,795,257
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Tp53 |
tumor protein p53 |
acts_upstream_of_or_within |
ISO |
MGI:2139971 (PMID:22904064) |
RGD |
PMID:22904064 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Vash1 |
vasohibin 1 |
acts_upstream_of_or_within |
ISO |
(PMID:23056314) |
RGD |
PMID:23056314 |
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NCBI chr 6:106,330,374...106,345,740
Ensembl chr 6:106,329,123...106,345,726
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Zfp277 |
zinc finger protein 277 |
acts_upstream_of_or_within |
ISO |
MGI:5496522 (PMID:20808772) |
RGD |
PMID:20808772 |
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NCBI chr 6:57,383,454...57,512,785
Ensembl chr 6:57,383,951...57,512,765
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Zmpste24 |
zinc metallopeptidase STE24 |
acts_upstream_of_or_within |
ISO |
MGI:1888594|MGI:2180033 (PMID:16079796), (PMID:21746928), (PMID:23686339) |
RGD |
PMID:16079796 PMID:21746928 PMID:23686339 |
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NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
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Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
acts_upstream_of_or_within |
ISO |
MGI:104738 (PMID:22729085) |
RGD |
PMID:22729085 |
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NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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Akt3 |
AKT serine/threonine kinase 3 |
involved_in |
ISO IEA |
(PMID:25323119) GO_REF:0000107 |
RGD Ensembl |
PMID:25323119 |
GO_REF:0000107 |
NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
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Ang |
angiogenin |
involved_in |
ISO |
(PMID:33758201) |
RGD |
PMID:33758201 |
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NCBI chr15:24,312,711...24,323,361
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Bcl2l12 |
Bcl2 like 12 |
acts_upstream_of_or_within |
ISO |
(PMID:20837658) |
RGD |
PMID:20837658 |
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NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991
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Bcl6 |
BCL6, transcription repressor |
acts_upstream_of_or_within |
ISO |
MGI:2158436 (PMID:23209284) |
RGD |
PMID:23209284 |
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NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
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Cdk6 |
cyclin-dependent kinase 6 |
involved_in |
ISO |
(PMID:17420273) |
RGD |
PMID:17420273 |
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NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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Fbxo5 |
F-box protein 5 |
involved_in |
ISO |
(PMID:17875940) |
RGD |
PMID:17875940 |
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NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
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Fzr1 |
fizzy and cell division cycle 20 related 1 |
involved_in |
ISO |
(PMID:21241890) |
RGD |
PMID:21241890 |
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NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952
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Gch1 |
GTP cyclohydrolase 1 |
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IMP |
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RGD |
PMID:30690003 |
RGD:401717569 |
NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
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Hmga2 |
high mobility group AT-hook 2 |
involved_in |
ISO |
(PMID:23072816) |
RGD |
PMID:23072816 |
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NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
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Mif |
macrophage migration inhibitory factor |
involved_in |
ISO |
(PMID:10562313) |
RGD |
PMID:10562313 |
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NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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Nampt |
nicotinamide phosphoribosyltransferase |
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IDA |
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RGD |
PMID:28125705 |
RGD:13781884 |
NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
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Plk2 |
polo-like kinase 2 |
involved_in |
IEA ISO |
GO_REF:0000107 (PMID:27908889) |
Ensembl RGD |
PMID:27908889 |
GO_REF:0000107 |
NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
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Prkdc |
protein kinase, DNA-activated, catalytic subunit |
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IMP |
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RGD |
PMID:22981234 |
RGD:8696027 |
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
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Pten |
phosphatase and tensin homolog |
involved_in |
ISO |
(PMID:21241890) |
RGD |
PMID:21241890 |
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NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Rbl1 |
RB transcriptional corepressor like 1 |
involved_in |
ISO IEA |
(PMID:28595801) GO_REF:0000107 |
RGD Ensembl |
PMID:28595801 |
GO_REF:0000107 |
NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
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Sirt1 |
sirtuin 1 |
involved_in |
ISO IEA |
(PMID:20203304), (PMID:20424141) GO_REF:0000107 |
RGD Ensembl |
PMID:20203304 PMID:20424141 |
GO_REF:0000107 |
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Sirt6 |
sirtuin 6 |
involved_in |
ISO |
(PMID:22753495), (PMID:27043296), (PMID:29474172) |
RGD |
PMID:22753495 PMID:27043296 PMID:29474172 |
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NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
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Tbx2 |
T-box transcription factor 2 |
involved_in |
ISO |
(PMID:11062467), (PMID:12000749) |
RGD |
PMID:11062467 PMID:12000749 |
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NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
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Terc |
telomerase RNA component |
involved_in |
ISO |
(PMID:11313459) |
RGD |
PMID:11313459 |
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NCBI chr 2:112,815,654...112,816,041
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Terf2 |
telomeric repeat binding factor 2 |
involved_in |
ISO |
(PMID:11927518) |
RGD |
PMID:11927518 |
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NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
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Tert |
telomerase reverse transcriptase |
involved_in |
ISO |
(PMID:11313459), (PMID:11927518) |
RGD |
PMID:11313459 PMID:11927518 |
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NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
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Tp63 |
tumor protein p63 |
involved_in |
ISO |
(PMID:19451233) |
RGD |
PMID:19451233 |
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NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
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Twist1 |
twist family bHLH transcription factor 1 |
involved_in |
ISO |
(PMID:17690110) |
RGD |
PMID:17690110 |
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NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
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Wnt1 |
Wnt family member 1 |
involved_in |
ISO |
(PMID:16501043) |
RGD |
PMID:16501043 |
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NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
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Ybx1 |
Y box binding protein 1 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:29712925) |
UniProt RGD |
PMID:29712925 |
GO_REF:0000024 |
NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862
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Zkscan3 |
zinc finger with KRAB and SCAN domains 3 |
involved_in |
ISO |
(PMID:23434374) |
RGD |
PMID:23434374 |
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NCBI chr17:43,217,168...43,232,828
Ensembl chr17:43,217,222...43,232,827
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Abi3 |
ABI family, member 3 |
involved_in |
ISO |
(PMID:21223585) |
RGD |
PMID:21223585 |
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NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816
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Abi3bp |
ABI family member 3 binding protein |
involved_in |
ISS |
GO_REF:0000024 |
ARUK-UCL |
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GO_REF:0000024 |
NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929
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Arg2 |
arginase 2 |
involved_in |
IEA ISO |
GO_REF:0000107 (PMID:22928666) |
Ensembl RGD |
PMID:22928666 |
GO_REF:0000107 |
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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B2m |
beta-2 microglobulin |
involved_in |
ISO IEA |
(PMID:28213472) GO_REF:0000107 |
RGD Ensembl |
PMID:28213472 |
GO_REF:0000107 |
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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Ccn1 |
cellular communication network factor 1 |
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IEP |
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RGD |
PMID:30371213 |
RGD:329845516 |
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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Cgas |
cyclic GMP-AMP synthase |
involved_in |
ISO |
(PMID:28759028) |
RGD |
PMID:28759028 |
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NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
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Eef1e1 |
eukaryotic translation elongation factor 1 epsilon 1 |
involved_in |
ISO |
(PMID:25465621) |
RGD |
PMID:25465621 |
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NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720
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Ilk |
integrin-linked kinase |
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IMP |
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RGD |
PMID:17234816 |
RGD:2301768 |
NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
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Kras |
KRAS proto-oncogene, GTPase |
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IMP |
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RGD |
PMID:17706954 |
RGD:11060281 |
NCBI chr 4:178,185,418...178,218,484
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Mir20b |
microRNA 20b |
involved_in |
ISO |
(PMID:28595801) |
RGD |
PMID:28595801 |
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NCBI chr X:132,422,211...132,422,282
Ensembl chr X:132,422,211...132,422,282
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Mir217 |
microRNA 217 |
involved_in |
ISO |
(PMID:19786632) |
RGD |
PMID:19786632 |
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NCBI chr14:102,531,505...102,531,609
Ensembl chr14:102,531,505...102,531,609
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Mir22 |
microRNA 22 |
involved_in |
ISO |
(PMID:25323119) |
RGD |
PMID:25323119 |
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NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
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Mir34a |
microRNA 34a |
involved_in |
ISO |
(PMID:20424141) |
RGD |
PMID:20424141 |
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NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
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Morc3 |
MORC family CW-type zinc finger 3 |
acts_upstream_of_or_within |
ISO |
(PMID:17332504) |
RGD |
PMID:17332504 |
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NCBI chr11:33,151,906...33,194,650
Ensembl chr11:33,152,025...33,194,646
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Mtor |
mechanistic target of rapamycin kinase |
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IMP |
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RGD |
PMID:19698731 |
RGD:10003167 |
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Pawr |
pro-apoptotic WT1 regulator |
involved_in |
ISO |
(PMID:25472717) |
RGD |
PMID:25472717 |
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NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
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RT1-M3-1 |
RT1 class Ib, locus M3, gene 1 |
involved_in |
ISO |
(PMID:23184984) |
RGD |
PMID:23184984 |
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NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
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Sirt1 |
sirtuin 1 |
involved_in |
ISO IEA |
(PMID:18687677) GO_REF:0000107 |
RGD Ensembl |
PMID:18687677 |
GO_REF:0000107 |
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Stk11 |
serine/threonine kinase 11 |
involved_in |
ISO |
(PMID:20203304) |
RGD |
PMID:20203304 |
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NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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Tp53 |
tumor protein p53 |
involved_in acts_upstream_of_or_within |
ISO IEA |
(PMID:29474172) GO_REF:0000107 MGI:1920086 (PMID:17053789) (PMID:10562313) |
RGD Ensembl |
PMID:10562313 PMID:17053789 PMID:29474172 |
GO_REF:0000107 |
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Ypel3 |
yippee-like 3 |
involved_in |
ISO |
(PMID:20388804) |
RGD |
PMID:20388804 |
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NCBI chr 1:181,384,385...181,387,706
Ensembl chr 1:181,384,357...181,387,705
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Term paths to the root
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