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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of stem cell differentiation
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Accession:GO:2000737 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.


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negative regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BBS12 Bardet-Biedl syndrome 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22958920) Ensembl
MGI		 PMID:22958920 GO_REF:0000107 NCBI chr19:17,537,840...17,550,443
Ensembl chr19:17,538,346...17,540,487 		JBrowse link
G CCNK cyclin K acts_upstream_of_or_within ISO (PMID:22547058) MGI PMID:22547058 NCBI chr 8:67,910,772...67,927,216
Ensembl chr 8:67,901,426...67,945,214 		JBrowse link
G CDK12 cyclin dependent kinase 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22547058) Ensembl
MGI		 PMID:22547058 GO_REF:0000107 NCBI chr 9:22,900,170...22,979,353
Ensembl chr 9:22,917,979...22,979,019 		JBrowse link
G CDK13 cyclin dependent kinase 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22547058) Ensembl
MGI		 PMID:22547058 GO_REF:0000107 NCBI chr18:9,801,350...9,920,401
Ensembl chr18:9,803,535...9,920,281 		JBrowse link
G ESRRB estrogen related receptor beta involved_in ISO (MGI:5887187|PMID:26206133) UniProt PMID:26206133 MGI:5887187 NCBI chr 8:49,253,877...49,424,148
Ensembl chr 8:49,253,332...49,421,332 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107
G HES5 hes family bHLH transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388 		JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:35,832,956...35,842,898
Ensembl chr 7:35,833,988...35,843,754 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:11,656,926...11,693,146
Ensembl chr24:11,657,416...11,692,199 		JBrowse link
G LBH LBH regulator of WNT signaling pathway involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:23,939,135...23,969,611
Ensembl chr17:23,938,772...24,022,140 		JBrowse link
G MIR125A microRNA mir-125a acts_upstream_of_or_within ISO (PMID:22751012) MGI PMID:22751012 NCBI chr 1:105,400,273...105,400,332
Ensembl chr 1:105,400,270...105,400,337 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:17940068) MGI PMID:17940068 NCBI chr27:37,262,558...37,266,449 JBrowse link
G NCOA3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO (PMID:22977234) MGI PMID:22977234 Ensembl chr24:34,585,305...34,728,674
Ensembl chr24:34,585,305...34,728,674 		JBrowse link
G NELFB negative elongation factor complex member B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,411,725...48,425,044
Ensembl chr 9:48,408,005...48,423,308 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25335925) Ensembl
MGI		 PMID:25335925 GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TBX3 T-box transcription factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18356246) Ensembl
MGI		 PMID:18356246 GO_REF:0000107 NCBI chr26:11,694,885...11,709,594
Ensembl chr26:11,696,565...11,708,918 		JBrowse link
G TRIM6 tripartite motif containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:28,595,887...28,611,562
Ensembl chr21:28,595,448...28,611,124 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20516196) Ensembl
MGI		 PMID:20516196 GO_REF:0000107 NCBI chr 5:29,394,760...29,495,977
Ensembl chr 5:29,394,541...29,496,251 		JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:71,760,232...71,791,420
Ensembl chr 2:71,760,312...71,792,527 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:45,746,952...45,751,268
Ensembl chr10:45,748,936...45,751,250 		JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G REST RE1 silencing transcription factor involved_in ISO (PMID:20942606) UniProt PMID:20942606 NCBI chr13:49,041,082...49,062,596
Ensembl chr13:49,041,047...49,059,388 		JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,327,086...11,437,799
Ensembl chr27:11,426,647...11,437,303 		JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:26,122,917...26,142,458
Ensembl chr11:26,121,499...26,142,434 		JBrowse link
G LOC100683370 thymosin beta-4 involved_in ISO (PMID:7694679) UniProt PMID:7694679 NCBI chr 1:21,127,694...21,128,346 JBrowse link
G N4BP2L2 NEDD4 binding protein 2 like 2 involved_in ISO (PMID:19506020) UniProt PMID:19506020 NCBI chr25:7,622,032...7,694,396
Ensembl chr25:7,623,670...7,694,398 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G TCF15 transcription factor 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:20,274,113...20,281,081
Ensembl chr24:20,274,050...20,280,270 		JBrowse link
G ZFP36 ZFP36 ring finger protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11588035) Ensembl
MGI		 PMID:11588035 GO_REF:0000107 NCBI chr 1:113,815,972...113,818,093
Ensembl chr 1:113,816,273...113,818,065 		JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
G REST RE1 silencing transcription factor involved_in ISO (PMID:18570921) UniProt PMID:18570921 NCBI chr13:49,041,082...49,062,596
Ensembl chr13:49,041,047...49,059,388 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    negative regulation of biological process 5778
      negative regulation of developmental process 1072
        negative regulation of cell differentiation 773
          negative regulation of stem cell differentiation 31
            negative regulation of cardioblast differentiation + 1
            negative regulation of hematopoietic stem cell differentiation 6
            negative regulation of mesenchymal stem cell differentiation + 2
            negative regulation of neural crest cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      cellular developmental process 4594
        cell differentiation 4593
          regulation of cell differentiation 1757
            regulation of stem cell differentiation 81
              negative regulation of stem cell differentiation 31
                negative regulation of cardioblast differentiation + 1
                negative regulation of hematopoietic stem cell differentiation 6
                negative regulation of mesenchymal stem cell differentiation + 2
                negative regulation of neural crest cell differentiation + 0
paths to the root