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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of stem cell differentiation
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Accession:GO:2000737 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.


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negative regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnk cyclin K acts_upstream_of_or_within ISO (MGI:5467199|PMID:22547058) RGD PMID:22547058 MGI:5467199 NCBI chr 6:132,090,235...132,113,560
Ensembl chr 6:132,090,218...132,113,557
JBrowse link
G Cdk12 cyclin-dependent kinase 12 acts_upstream_of_or_within ISO (MGI:5467199|PMID:22547058) RGD PMID:22547058 MGI:5467199 NCBI chr10:86,157,186...86,210,657
Ensembl chr10:86,157,608...86,222,707
JBrowse link
G Cdk13 cyclin-dependent kinase 13 acts_upstream_of_or_within ISO (MGI:5467199|PMID:22547058) RGD PMID:22547058 MGI:5467199 NCBI chr17:49,833,194...49,922,932
Ensembl chr17:49,833,400...49,921,550
JBrowse link
G Esrrb estrogen-related receptor beta involved_in ISS
ISO
GO_REF:0000024
(MGI:5887187|PMID:26206133)
UniProt
RGD
PMID:26206133 GO_REF:0000024 MGI:5887187 NCBI chr 6:110,360,940...110,458,406
Ensembl chr 6:110,410,141...110,455,906
JBrowse link
G H1f8 H1.8 linker histone involved_in ISS
ISO
GO_REF:0000024
(MGI:5559660|PMID:22868987)
CAFA
RGD
PMID:22868987 GO_REF:0000024 MGI:5559660 NCBI chr 4:147,844,658...147,849,779
Ensembl chr 4:147,844,658...147,849,779
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19682396)
Ensembl
RGD
PMID:19682396 GO_REF:0000107 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO
ISS
(PMID:19682396)
GO_REF:0000024
RGD
UniProt
PMID:19682396 GO_REF:0000024 NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5908336|PMID:21235343)
(PMID:21235343)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21235343 GO_REF:0000024 GO_REF:0000107 MGI:5908336 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in ISO
IEA
(PMID:19682396)
GO_REF:0000107
RGD
Ensembl
PMID:19682396 GO_REF:0000107 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Lbh LBH regulator of WNT signaling pathway involved_in ISO (MGI:5634223|PMID:25655704) RGD PMID:25655704 MGI:5634223 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Mir125a microRNA 125a acts_upstream_of_or_within ISO MGI:1921298 (MGI:5465045|PMID:22751012) RGD PMID:22751012 MGI:5465045 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO (MGI:5467164|PMID:22977234) RGD PMID:22977234 MGI:5467164 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
G Nelfb negative elongation factor complex member B involved_in ISO (MGI:3845453|PMID:19340312) RGD PMID:19340312 MGI:3845453 NCBI chr 3:2,414,448...2,431,148
Ensembl chr 3:2,414,451...2,431,148
JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:19682396) RGD PMID:19682396 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (MGI:5659778|PMID:25335925) RGD PMID:25335925 MGI:5659778 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (MGI:5492022|PMID:22328504) RGD PMID:22328504 MGI:5492022 NCBI chr 1:169,410,084...169,423,305
Ensembl chr 1:169,410,115...169,423,283
JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO (MGI:4455217|PMID:20516196) RGD PMID:20516196 MGI:4455217 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 involved_in ISO
IEA
(PMID:32169943)
GO_REF:0000107
RGD
Ensembl
PMID:32169943 GO_REF:0000107 NCBI chr 5:150,364,490...150,390,173
Ensembl chr 5:150,365,101...150,390,099
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO (MGI:5500826|PMID:23748442) RGD PMID:23748442 MGI:5500826 NCBI chr 6:7,417,416...7,423,447
Ensembl chr 6:7,417,425...7,421,456
JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rest RE1-silencing transcription factor involved_in ISO
ISS
IEA
(PMID:20942606)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:20942606 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO
IEA
(PMID:21199191)
GO_REF:0000107
RGD
Ensembl
PMID:21199191 GO_REF:0000107 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa9 heat shock protein family A (Hsp70) member 9 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5784980|PMID:21123823)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:21123823 GO_REF:0000024 GO_REF:0000107 MGI:5784980 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 involved_in ISO (PMID:19506020) RGD PMID:19506020 NCBI chr12:627,128...650,604
Ensembl chr12:628,488...650,376
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 involved_in ISO (MGI:5476857|PMID:23434824) RGD PMID:23434824 MGI:5476857 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Tcf15 transcription factor 15 involved_in IEA
ISO
GO_REF:0000107
(MGI:6479302|PMID:32669716)
Ensembl
RGD
PMID:32669716 GO_REF:0000107 MGI:6479302 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504
JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir154 microRNA 154 acts_upstream_of_or_within ISO (MGI:5705446|PMID:25959411) RGD PMID:25959411 MGI:5705446 NCBI chr 6:133,888,586...133,888,669
Ensembl chr 6:133,888,586...133,888,669
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO (PMID:18570921) RGD PMID:18570921 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    negative regulation of biological process 5607
      negative regulation of developmental process 1018
        negative regulation of cell differentiation 737
          negative regulation of stem cell differentiation 27
            negative regulation of cardioblast differentiation + 2
            negative regulation of hematopoietic stem cell differentiation 4
            negative regulation of mesenchymal stem cell differentiation + 2
            negative regulation of neural crest cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 19599
    cellular process 18451
      cellular developmental process 4460
        cell differentiation 4364
          regulation of cell differentiation 1699
            regulation of stem cell differentiation 67
              negative regulation of stem cell differentiation 27
                negative regulation of cardioblast differentiation + 2
                negative regulation of hematopoietic stem cell differentiation 4
                negative regulation of mesenchymal stem cell differentiation + 2
                negative regulation of neural crest cell differentiation + 0
paths to the root