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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of stem cell differentiation
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Accession:GO:2000736 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of stem cell differentiation.


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regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DICER1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (MGI:3528782|PMID:15713842) MGI PMID:15713842 MGI:3528782 NCBI chr 7:116,361,630...116,436,471
Ensembl chr 7:116,361,630...116,436,519
JBrowse link
G KDM3A lysine demethylase 3A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3759699|PMID:17938240) Ensembl
MGI
PMID:17938240 GO_REF:0000107 MGI:3759699 NCBI chr 3:58,300,109...58,355,000
Ensembl chr 3:58,299,706...58,354,941
JBrowse link
G KDM4C lysine demethylase 4C acts_upstream_of_or_within ISO (MGI:3759699|PMID:17938240) MGI PMID:17938240 MGI:3759699 NCBI chr 1:215,071,335...215,507,778
Ensembl chr 1:215,071,334...215,507,800
JBrowse link
G NSUN2 NOP2/Sun RNA methyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:75,335,565...75,414,659
Ensembl chr16:75,335,246...75,367,184
JBrowse link
G OCIAD1 OCIA domain containing 1 involved_in ISO (MGI:5908327|PMID:23972987) UniProt PMID:23972987 MGI:5908327 NCBI chr 8:38,745,415...38,769,255 JBrowse link
G PRDM4 PR/SET domain 4 involved_in ISO PMID:23048031 ParkinsonsUK-UCL PMID:23048031 RGD:10054084 NCBI chr 5:12,638,335...12,668,890
Ensembl chr 5:12,638,488...12,668,878
JBrowse link
G SMYD5 SMYD family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,552,731...69,566,013
Ensembl chr 3:69,552,731...69,571,128
JBrowse link
G SMYD5 SMYD family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,566,112...69,571,165
Ensembl chr 3:69,552,731...69,571,128
JBrowse link
G TEAD2 TEA domain transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5317256|PMID:21385842) Ensembl
MGI
PMID:21385842 GO_REF:0000107 MGI:5317256 NCBI chr 6:54,448,183...54,462,325
Ensembl chr 6:54,448,183...54,462,304
JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100621006 RE1-silencing transcription factor-like involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
G REST RE1 silencing transcription factor involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:56,035,182...56,061,140
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:73,707,026...73,826,529
Ensembl chr 5:73,707,022...73,826,431
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:51,153,978...51,203,678
Ensembl chr 2:51,154,086...51,202,176
JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:140,515,239...140,532,164
Ensembl chr 2:140,515,246...140,531,845
JBrowse link
G N4BP2L2 NEDD4 binding protein 2 like 2 involved_in ISO (PMID:19506020) UniProt PMID:19506020 NCBI chr11:8,891,053...8,997,810 JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G TCF15 transcription factor 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,626,682...34,632,881
Ensembl chr17:34,626,706...34,632,388
JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100621006 RE1-silencing transcription factor-like involved_in ISO (PMID:18570921) UniProt PMID:18570921 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013
JBrowse link
negative regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNK cyclin K acts_upstream_of_or_within ISO (MGI:5467199|PMID:22547058) MGI PMID:22547058 MGI:5467199 NCBI chr 7:120,487,140...120,514,223
Ensembl chr 7:120,487,206...120,514,014
JBrowse link
G CDK12 cyclin dependent kinase 12 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5467199|PMID:22547058) Ensembl
MGI
PMID:22547058 GO_REF:0000107 MGI:5467199 NCBI chr12:22,755,365...22,831,397
Ensembl chr12:22,755,909...22,831,333
JBrowse link
G CDK13 cyclin dependent kinase 13 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5467199|PMID:22547058) Ensembl
MGI
PMID:22547058 GO_REF:0000107 MGI:5467199 NCBI chr18:54,310,311...54,430,060
Ensembl chr18:54,308,144...54,429,939
JBrowse link
G ESRRB estrogen related receptor beta involved_in ISO (MGI:5887187|PMID:26206133) UniProt PMID:26206133 MGI:5887187 NCBI chr 7:99,511,135...99,699,478
Ensembl chr 7:99,514,168...99,699,011
JBrowse link
G H1FOO oocyte-specific H1 histone involved_in ISS UniProt GO_REF:0000024 NCBI chr13:68,921,491...68,943,061
Ensembl chr13:68,938,024...68,942,744
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:131,135,970...131,137,865
Ensembl chr13:131,135,724...131,138,236
JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:64,409,110...64,410,541
Ensembl chr 6:64,409,115...64,411,006
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:17,475,266...17,497,060
Ensembl chr10:17,475,270...17,497,130
JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:19,591,248...19,629,659
Ensembl chr17:19,591,252...19,630,085
JBrowse link
G LBH LBH regulator of WNT signaling pathway involved_in ISO (MGI:5634223|PMID:25655704) CAFA PMID:25655704 MGI:5634223 NCBI chr 3:109,078,285...109,113,536 JBrowse link
G LOC100622028 tripartite motif-containing protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,197,922...4,204,688
Ensembl chr 9:4,197,922...4,204,664
JBrowse link
G MIR125A microRNA mir-125a acts_upstream_of_or_within ISO (MGI:5465045|PMID:22751012) MGI PMID:22751012 MGI:5465045 NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
JBrowse link
G NCOA3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO (MGI:5467164|PMID:22977234) MGI PMID:22977234 MGI:5467164 NCBI chr17:49,528,275...49,660,471
Ensembl chr17:49,528,164...49,663,203
JBrowse link
G NELFB negative elongation factor complex member B involved_in ISO (MGI:3845453|PMID:19340312) UniProt PMID:19340312 MGI:3845453
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107
G STAT3 signal transducer and activator of transcription 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5659778|PMID:25335925) Ensembl
MGI
PMID:25335925 GO_REF:0000107 MGI:5659778 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993
JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4455217|PMID:20516196) Ensembl
MGI
PMID:20516196 GO_REF:0000107 MGI:4455217 NCBI chr 9:32,811,629...32,924,926
Ensembl chr 9:32,811,416...32,925,603
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:85,717,147...85,756,750
Ensembl chr 6:85,716,917...85,751,583
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:97,200,395...97,203,094
Ensembl chr 3:97,200,406...97,204,700
JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHX36 DEAH-box helicase 36 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:94,298,790...94,350,333
Ensembl chr13:94,298,790...94,350,312
JBrowse link
G GATA4 GATA binding protein 4 acts_upstream_of_or_within ISO (PMID:16137232) BHF-UCL PMID:16137232 NCBI chr14:14,858,470...14,938,156
Ensembl chr14:14,858,159...14,939,941
JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (PMID:16137232) BHF-UCL PMID:16137232 NCBI chr 6:107,282,709...107,314,725
Ensembl chr 6:107,282,847...107,314,634
JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in ISO (MGI:3784761|PMID:11889119) BHF-UCL PMID:11889119 MGI:3784761 NCBI chr16:51,086,014...51,089,165
Ensembl chr16:51,086,011...51,089,165
JBrowse link
G TBX5 T-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:37,772,205...37,826,015
Ensembl chr14:37,773,605...37,824,400
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr10:8,306,136...8,435,307
Ensembl chr10:8,305,424...8,405,771
JBrowse link
positive regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXC1 forkhead box C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:837,088...840,593
Ensembl chr 7:837,171...838,805
JBrowse link
positive regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,701,455...6,720,191
Ensembl chr 2:6,701,340...6,720,172
JBrowse link
G SOX5 SRY-box transcription factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:49,159,950...50,166,463
Ensembl chr 5:49,160,723...50,161,570
JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in ISO (PMID:21401405) UniProt PMID:21401405 NCBI chr 2:42,447,391...43,068,824
Ensembl chr 2:42,448,216...43,068,325
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315
JBrowse link
positive regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta acts_upstream_of_or_within ISO (MGI:5319061|PMID:22064483) MGI PMID:22064483 MGI:5319061 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,574
JBrowse link
G HOXB4 homeobox B4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:24,830,453...24,832,534 JBrowse link
G MIR100 microRNA mir-100 acts_upstream_of_or_within ISO (MGI:4822296|PMID:20439489) MGI PMID:20439489 MGI:4822296 NCBI chr 9:49,157,909...49,157,988
Ensembl chr 9:49,157,909...49,157,988
JBrowse link
G MIR137 microRNA mir-137 acts_upstream_of_or_within ISO (MGI:4822296|PMID:20439489) MGI PMID:20439489 MGI:4822296 NCBI chr 4:119,793,993...119,794,074
Ensembl chr 4:119,793,984...119,794,088
JBrowse link
G NUDT21 nudix hydrolase 21 involved_in ISO (MGI:6110185|PMID:29249356) UniProt PMID:29249356 MGI:6110185 NCBI chr 6:29,339,893...29,359,596
Ensembl chr 6:29,339,841...29,363,315
JBrowse link
G PTN pleiotrophin involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr18:12,219,708...12,309,045
Ensembl chr18:12,219,790...12,311,922
JBrowse link
G PWP1 PWP1 homolog, endonuclein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5659778|PMID:25335925) Ensembl
MGI
PMID:25335925 GO_REF:0000107 MGI:5659778 NCBI chr 5:12,703,067...12,730,884
Ensembl chr 5:12,701,584...12,730,850
JBrowse link
G RBM24 RNA binding motif protein 24 involved_in ISO (PMID:26990106) UniProt PMID:26990106 NCBI chr 7:13,126,518...13,139,504 JBrowse link
G SP7 Sp7 transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:18,541,368...18,566,668
Ensembl chr 5:18,540,952...18,575,436
JBrowse link
G TACSTD2 tumor associated calcium signal transducer 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5440097|PMID:23070813)
GO_Central
MGI
PMID:21873635 PMID:23070813 MGI:5440097 NCBI chr 6:153,859,488...153,861,508
Ensembl chr 6:153,859,482...153,861,492
JBrowse link
G TCF15 transcription factor 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,626,682...34,632,881
Ensembl chr17:34,626,706...34,632,388
JBrowse link
G VSIR V-set immunoregulatory receptor acts_upstream_of_or_within ISO (MGI:5465045|PMID:22751012) MGI PMID:22751012 MGI:5465045 NCBI chr14:74,667,081...74,693,347
Ensembl chr14:74,666,624...74,693,281
JBrowse link
regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK6 cyclin dependent kinase 6 acts_upstream_of_or_within ISO (MGI:5636128|PMID:25342715) MGI PMID:25342715 MGI:5636128 NCBI chr 9:72,510,858...72,765,631
Ensembl chr 9:72,518,101...72,764,129
JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:103,041,029...103,096,741
Ensembl chr 3:103,041,224...103,096,738
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,359...79,847,281
JBrowse link
G PUS7 pseudouridine synthase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:105,325,762...105,388,972
Ensembl chr 9:105,319,220...105,445,671
JBrowse link
G SETD1A SET domain containing 1A, histone lysine methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,463,768...17,490,397
Ensembl chr 3:17,463,768...17,488,594
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:85,717,147...85,756,750
Ensembl chr 6:85,716,917...85,751,583
JBrowse link
regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR21 microRNA mir-21 ISO RGD PMID:27798620 RGD:41404703 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:40,966,568...41,021,440
Ensembl chr 8:40,967,493...41,021,442
JBrowse link
G SLC4A11 solute carrier family 4 member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,445,360...32,458,246
Ensembl chr17:32,446,471...32,459,398
JBrowse link
regulation of neural crest cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr14:87,743,270...87,891,790
Ensembl chr14:87,742,459...87,891,793
JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr14:87,743,270...87,891,790
Ensembl chr14:87,742,459...87,891,793
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    developmental process 6309
      regulation of developmental process 2536
        regulation of cell differentiation 1631
          regulation of stem cell differentiation 67
            negative regulation of stem cell differentiation + 27
            positive regulation of stem cell differentiation + 23
            regulation of cardioblast differentiation + 8
            regulation of hematopoietic stem cell differentiation + 11
            regulation of mesenchymal stem cell differentiation + 9
            regulation of neural crest cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 16579
    cellular process 15862
      cellular developmental process 4176
        cell differentiation 4088
          regulation of cell differentiation 1631
            regulation of stem cell differentiation 67
              negative regulation of stem cell differentiation + 27
              positive regulation of stem cell differentiation + 23
              regulation of cardioblast differentiation + 8
              regulation of hematopoietic stem cell differentiation + 11
              regulation of mesenchymal stem cell differentiation + 9
              regulation of neural crest cell differentiation + 1
paths to the root