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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of stem cell differentiation
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Accession:GO:2000736 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of stem cell differentiation.


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regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DICER1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (MGI:3528782|PMID:15713842) MGI PMID:15713842 MGI:3528782 NCBI chr14:95,086,228...95,158,263
Ensembl chr14:95,086,228...95,158,010
JBrowse link
G GDNF glial cell derived neurotrophic factor involved_in TAS (PMID:23626767) ParkinsonsUK-UCL PMID:23626767 NCBI chr 5:37,812,677...37,840,044
Ensembl chr 5:37,812,677...37,840,041
JBrowse link
G KDM3A lysine demethylase 3A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3759699|PMID:17938240) Ensembl
MGI
PMID:17938240 GO_REF:0000107 MGI:3759699 NCBI chr 2:86,440,647...86,492,716
Ensembl chr 2:86,440,647...86,492,716
JBrowse link
G KDM4C lysine demethylase 4C acts_upstream_of_or_within ISO (MGI:3759699|PMID:17938240) MGI PMID:17938240 MGI:3759699 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,720,863...7,175,648
JBrowse link
G NSUN2 NOP2/Sun RNA methyltransferase 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:6,599,239...6,633,044
Ensembl chr 5:6,599,239...6,633,291
JBrowse link
G OCIAD1 OCIA domain containing 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:48,830,924...48,861,815
Ensembl chr 4:48,805,212...48,861,817
JBrowse link
G PRDM4 PR/SET domain 4 involved_in ISO PMID:23048031 ParkinsonsUK-UCL PMID:23048031 RGD:10054084 NCBI chr12:107,732,866...107,761,272
Ensembl chr12:107,732,871...107,761,272
JBrowse link
G SMYD5 SMYD family member 5 involved_in ISS
IMP
(PMID:28951459) UniProt PMID:28951459 GO_REF:0000024 NCBI chr 2:73,214,245...73,227,221
Ensembl chr 2:73,214,222...73,227,221
JBrowse link
G TEAD2 TEA domain transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5317256|PMID:21385842) Ensembl
MGI
PMID:21385842 GO_REF:0000107 MGI:5317256 NCBI chr19:49,340,595...49,362,452
Ensembl chr19:49,340,595...49,362,457
JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G REST RE1 silencing transcription factor involved_in IMP (PMID:20942606) UniProt PMID:20942606 NCBI chr 4:56,907,900...56,935,847
Ensembl chr 4:56,907,876...56,966,808
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IDA (PMID:21199191) UniProt PMID:21199191 NCBI chr12:42,456,757...42,589,755
Ensembl chr12:42,456,757...42,590,355
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in IDA (PMID:19736317) BHF-UCL PMID:19736317 NCBI chr 1:228,006,998...228,067,113
Ensembl chr 1:228,006,998...228,061,271
JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675
JBrowse link
G N4BP2L2 NEDD4 binding protein 2 like 2 involved_in IMP (PMID:19506020) UniProt PMID:19506020 NCBI chr13:32,432,485...32,542,710
Ensembl chr13:32,432,417...32,538,885
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G TCF15 transcription factor 15 involved_in ISS UniProt GO_REF:0000024 NCBI chr20:604,257...610,309
Ensembl chr20:604,257...610,309
JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR154 microRNA 154 acts_upstream_of_or_within ISO (MGI:5705446|PMID:25959411) MGI PMID:25959411 MGI:5705446 NCBI chr14:101,059,755...101,059,838
Ensembl chr14:101,059,755...101,059,838
JBrowse link
G REST RE1 silencing transcription factor involved_in IMP (PMID:18570921) UniProt PMID:18570921 NCBI chr 4:56,907,900...56,935,847
Ensembl chr 4:56,907,876...56,966,808
JBrowse link
negative regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNK cyclin K acts_upstream_of_or_within ISO (MGI:5467199|PMID:22547058) MGI PMID:22547058 MGI:5467199 NCBI chr14:99,481,409...99,512,440
Ensembl chr14:99,481,169...99,535,044
JBrowse link
G CDK12 cyclin dependent kinase 12 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5467199|PMID:22547058) Ensembl
MGI
PMID:22547058 GO_REF:0000107 MGI:5467199 NCBI chr17:39,461,486...39,567,560
Ensembl chr17:39,461,486...39,564,907
JBrowse link
G CDK13 cyclin dependent kinase 13 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5467199|PMID:22547058) Ensembl
MGI
PMID:22547058 GO_REF:0000107 MGI:5467199 NCBI chr 7:39,949,664...40,099,580
Ensembl chr 7:39,950,121...40,099,580
JBrowse link
G ESRRB estrogen related receptor beta involved_in ISS UniProt GO_REF:0000024 NCBI chr14:76,371,271...76,501,839
Ensembl chr14:76,310,712...76,501,837
JBrowse link
G H1-8 H1.8 linker histone involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:129,543,175...129,555,185
Ensembl chr 3:129,543,175...129,551,467
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in IMP (PMID:19682396) UniProt PMID:19682396 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in IMP (PMID:19682396) UniProt PMID:19682396 NCBI chr 1:2,528,745...2,530,554
Ensembl chr 1:2,528,745...2,530,263
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IMP
ISS
(PMID:21235343) UniProt PMID:21235343 GO_REF:0000024 NCBI chr 1:244,850,297...244,864,543
Ensembl chr 1:244,840,638...244,864,560
JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in IMP (PMID:19682396) UniProt PMID:19682396 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
JBrowse link
G LBH LBH regulator of WNT signaling pathway involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:30,231,534...30,260,028
Ensembl chr 2:30,231,534...30,323,730
JBrowse link
G MIR125A microRNA 125a acts_upstream_of_or_within ISO (MGI:5465045|PMID:22751012) MGI PMID:22751012 MGI:5465045 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339
JBrowse link
G NCOA3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO (MGI:5467164|PMID:22977234) MGI PMID:22977234 MGI:5467164 NCBI chr20:47,501,887...47,656,872
Ensembl chr20:47,501,887...47,656,877
JBrowse link
G NELFB negative elongation factor complex member B involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:137,255,327...137,273,542
Ensembl chr 9:137,255,327...137,273,542
JBrowse link
G NOTCH1 notch receptor 1 involved_in IMP (PMID:19682396) UniProt PMID:19682396 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G STAT3 signal transducer and activator of transcription 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5659778|PMID:25335925) MGI
Ensembl
PMID:25335925 GO_REF:0000107 MGI:5659778 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,540
JBrowse link
G TRIM6 tripartite motif containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958
JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4455217|PMID:20516196) Ensembl
MGI
PMID:20516196 GO_REF:0000107 MGI:4455217 NCBI chr11:102,109,957...102,233,424
Ensembl chr11:102,110,447...102,233,424
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 involved_in IMP (PMID:32169943) UniProt PMID:32169943 NCBI chr 1:28,736,624...28,769,775
Ensembl chr 1:28,736,621...28,769,775
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:43,222,402...43,226,606
Ensembl chr 2:43,222,402...43,226,606
JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHX36 DEAH-box helicase 36 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:154,272,546...154,324,487
Ensembl chr 3:154,272,546...154,324,487
JBrowse link
G GATA4 GATA binding protein 4 involved_in
acts_upstream_of_or_within
ISS
ISO
(PMID:16137232) BHF-UCL
BHF-UCL
PMID:16137232 GO_REF:0000024 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16137232) Ensembl
BHF-UCL
PMID:16137232 GO_REF:0000107 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in ISS (PMID:8900537) BHF-UCL PMID:8900537 NCBI chr 5:173,232,109...173,235,321
Ensembl chr 5:173,232,109...173,235,311
JBrowse link
G TBX5 T-box transcription factor 5 involved_in IDA (PMID:11431700) UniProt PMID:11431700 NCBI chr12:114,353,911...114,408,708
Ensembl chr12:114,353,911...114,408,442
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IDA (PMID:15896309) UniProt PMID:15896309 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
positive regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXC1 forkhead box C1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:1,609,915...1,613,897
Ensembl chr 6:1,609,915...1,613,897
JBrowse link
positive regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in IMP (PMID:18672106) UniProt PMID:18672106 NCBI chr11:65,538,559...65,558,389
Ensembl chr11:65,538,559...65,558,930
JBrowse link
G SOX5 SRY-box transcription factor 5 involved_in IDA (PMID:21401405) UniProt PMID:21401405 NCBI chr12:23,529,499...24,562,701
Ensembl chr12:23,529,504...24,562,544
JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in IDA (PMID:21401405) UniProt PMID:21401405 NCBI chr11:15,966,449...16,738,477
Ensembl chr11:15,966,449...16,739,591
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in IDA (PMID:21401405) UniProt PMID:21401405 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
positive regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta acts_upstream_of_or_within ISO (MGI:5319061|PMID:22064483) MGI PMID:22064483 MGI:5319061 NCBI chr 3:119,821,321...120,095,823
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G HOXB4 homeobox B4 involved_in IDA (PMID:18932205) BHF-UCL PMID:18932205 NCBI chr17:48,575,507...48,578,350
Ensembl chr17:48,575,507...48,578,350
JBrowse link
G MIR100 microRNA 100 acts_upstream_of_or_within ISO (MGI:4822296|PMID:20439489) MGI PMID:20439489 MGI:4822296 NCBI chr11:122,152,229...122,152,308
Ensembl chr11:122,152,229...122,152,308
JBrowse link
G MIR137 microRNA 137 acts_upstream_of_or_within ISO (MGI:4822296|PMID:20439489) MGI PMID:20439489 MGI:4822296 NCBI chr 1:98,046,070...98,046,171
Ensembl chr 1:98,046,070...98,046,171
JBrowse link
G MIR34A microRNA 34a acts_upstream_of_or_within ISO (MGI:4822296|PMID:20439489) MGI PMID:20439489 MGI:4822296 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777
JBrowse link
G NUDT21 nudix hydrolase 21 involved_in ISS UniProt GO_REF:0000024 NCBI chr16:56,429,133...56,451,332
Ensembl chr16:56,429,133...56,452,199
JBrowse link
G PTN pleiotrophin involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774
JBrowse link
G PWP1 PWP1 homolog, endonuclein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5659778|PMID:25335925) Ensembl
MGI
PMID:25335925 GO_REF:0000107 MGI:5659778 NCBI chr12:107,685,799...107,713,162
Ensembl chr12:107,685,799...107,713,162
JBrowse link
G RBM24 RNA binding motif protein 24 involved_in IMP (PMID:26990106) UniProt PMID:26990106 NCBI chr 6:17,281,361...17,293,875
Ensembl chr 6:17,281,361...17,293,871
JBrowse link
G SP7 Sp7 transcription factor involved_in IDA (PMID:18932205) BHF-UCL PMID:18932205 NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315
JBrowse link
G TACSTD2 tumor associated calcium signal transducer 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5440097|PMID:23070813)
GO_Central
MGI
PMID:21873635 PMID:23070813 MGI:5440097 NCBI chr 1:58,575,433...58,577,252
Ensembl chr 1:58,575,433...58,577,252
JBrowse link
G TCF15 transcription factor 15 involved_in ISS UniProt GO_REF:0000024 NCBI chr20:604,257...610,309
Ensembl chr20:604,257...610,309
JBrowse link
G VSIR V-set immunoregulatory receptor acts_upstream_of_or_within ISO (MGI:5465045|PMID:22751012) MGI PMID:22751012 MGI:5465045 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-8939236 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G CDK6 cyclin dependent kinase 6 acts_upstream_of_or_within ISO (MGI:5636128|PMID:25342715) MGI PMID:25342715 MGI:5636128 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573
JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:37,099,210...37,157,065
Ensembl chr 2:37,099,210...37,157,522
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in TAS Reactome Reactome:R-HSA-8939236 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,241...34,540,748
JBrowse link
G METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISS UniProt GO_REF:0000024 NCBI chr14:21,498,138...21,511,340
Ensembl chr14:21,498,133...21,511,342
JBrowse link
G OSM oncostatin M involved_in TAS (PMID:1542793) GO_Central PMID:1542793 NCBI chr22:30,262,829...30,266,851
Ensembl chr22:30,262,829...30,266,851
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178
JBrowse link
G PUS7 pseudouridine synthase 7 involved_in IMP (PMID:29628141) UniProt PMID:29628141 NCBI chr 7:105,456,501...105,522,271
Ensembl chr 7:105,439,661...105,522,271
JBrowse link
G SETD1A SET domain containing 1A, histone lysine methyltransferase involved_in IDA (PMID:27141965) ParkinsonsUK-UCL PMID:27141965 NCBI chr16:30,956,618...30,984,664
Ensembl chr16:30,957,754...30,984,664
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:28,736,624...28,769,775
Ensembl chr 1:28,736,621...28,769,775
JBrowse link
regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR21 microRNA 21 ISO RGD PMID:27798620 RGD:41404703 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in IMP (PMID:21596750) UniProt PMID:21596750 NCBI chr 4:54,229,127...54,298,245
Ensembl chr 4:54,229,280...54,298,245
JBrowse link
G SLC4A11 solute carrier family 4 member 11 involved_in ISS UniProt GO_REF:0000024 NCBI chr20:3,227,417...3,241,484
Ensembl chr20:3,227,417...3,239,559
JBrowse link
regulation of neural crest cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr10:86,755,786...86,927,969
Ensembl chr10:86,756,601...86,932,825
JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr10:86,755,786...86,927,969
Ensembl chr10:86,756,601...86,932,825
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    developmental process 7222
      regulation of developmental process 2771
        regulation of cell differentiation 1790
          regulation of stem cell differentiation 72
            negative regulation of stem cell differentiation + 27
            positive regulation of stem cell differentiation + 24
            regulation of cardioblast differentiation + 8
            regulation of hematopoietic stem cell differentiation + 15
            regulation of mesenchymal stem cell differentiation + 9
            regulation of neural crest cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 18537
    cellular process 17456
      cellular developmental process 4815
        cell differentiation 4708
          regulation of cell differentiation 1790
            regulation of stem cell differentiation 72
              negative regulation of stem cell differentiation + 27
              positive regulation of stem cell differentiation + 24
              regulation of cardioblast differentiation + 8
              regulation of hematopoietic stem cell differentiation + 15
              regulation of mesenchymal stem cell differentiation + 9
              regulation of neural crest cell differentiation + 1
paths to the root