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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of stem cell differentiation
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Accession:GO:2000736 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of stem cell differentiation.


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regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DICER1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (MGI:3528782|PMID:15713842) MGI PMID:15713842 MGI:3528782 NCBI chr14:75,709,029...75,780,779
Ensembl chr14:95,036,385...95,107,940
JBrowse link
G KDM3A lysine demethylase 3A acts_upstream_of_or_within ISO (MGI:3759699|PMID:17938240) MGI PMID:17938240 MGI:3759699 NCBI chr2A:86,497,531...86,548,772 JBrowse link
G KDM4C lysine demethylase 4C acts_upstream_of_or_within ISO (MGI:3759699|PMID:17938240) MGI PMID:17938240 MGI:3759699 NCBI chr 9:6,568,569...6,978,741
Ensembl chr 9:6,746,265...7,155,298
JBrowse link
G NSUN2 NOP2/Sun RNA methyltransferase 2 involved_in ISO (MGI:5304206|PMID:22144916) UniProt PMID:22144916 MGI:5304206 NCBI chr 5:6,921,073...6,953,622
Ensembl chr 5:6,596,414...6,629,121
JBrowse link
G OCIAD1 OCIA domain containing 1 involved_in ISO (MGI:5908327|PMID:23972987) UniProt PMID:23972987 MGI:5908327 NCBI chr 4:73,293,733...73,323,889
Ensembl chr 4:84,022,716...84,052,739
JBrowse link
G PRDM4 PR/SET domain 4 involved_in ISO PMID:23048031 ParkinsonsUK-UCL PMID:23048031 RGD:10054084 NCBI chr12:105,303,009...105,331,305
Ensembl chr12:108,699,444...108,727,304
JBrowse link
G SMYD5 SMYD family member 5 involved_in ISO (PMID:28951459)
(MGI:6103640|PMID:28951459), (MGI:6709288|PMID:28250819)
UniProt PMID:28250819 PMID:28951459 MGI:6103640 MGI:6709288 NCBI chr2A:73,267,007...73,280,006
Ensembl chr2A:74,755,794...74,768,776
JBrowse link
G TEAD2 TEA domain transcription factor 2 acts_upstream_of_or_within ISO (MGI:5317256|PMID:21385842) MGI PMID:21385842 MGI:5317256 NCBI chr19:46,355,283...46,377,224
Ensembl chr19:55,280,287...55,299,341
JBrowse link
negative regulation of amniotic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G REST RE1 silencing transcription factor involved_in ISO (PMID:20942606) UniProt PMID:20942606 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRICKLE1 prickle planar cell polarity protein 1 involved_in ISO (PMID:21199191) UniProt PMID:21199191 NCBI chr12:46,127,673...46,262,333
Ensembl chr12:47,100,393...47,126,102
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469
JBrowse link
negative regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA9 heat shock protein family A (Hsp70) member 9 involved_in ISO (MGI:5784980|PMID:21123823) UniProt PMID:21123823 MGI:5784980 NCBI chr 5:133,934,859...133,955,048
Ensembl chr 5:140,064,207...140,084,551
JBrowse link
G N4BP2L2 NEDD4 binding protein 2 like 2 involved_in ISO (PMID:19506020) UniProt PMID:19506020 NCBI chr13:13,691,326...13,803,162
Ensembl chr13:32,133,603...32,231,003
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 involved_in ISO (MGI:5476857|PMID:23434824) CACAO PMID:23434824 MGI:5476857 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G TCF15 transcription factor 15 involved_in ISO (MGI:6479302|PMID:32669716) UniProt PMID:32669716 MGI:6479302 NCBI chr20:811,907...817,971 JBrowse link
negative regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G REST RE1 silencing transcription factor involved_in ISO (PMID:18570921) UniProt PMID:18570921 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242
JBrowse link
negative regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNK cyclin K acts_upstream_of_or_within ISO (MGI:5467199|PMID:22547058) MGI PMID:22547058 MGI:5467199 NCBI chr14:80,105,372...80,136,511
Ensembl chr14:99,438,814...99,480,842
JBrowse link
G CDK12 cyclin dependent kinase 12 acts_upstream_of_or_within ISO (MGI:5467199|PMID:22547058) MGI PMID:22547058 MGI:5467199 NCBI chr17:17,721,266...17,826,521
Ensembl chr17:17,970,248...18,040,763
JBrowse link
G CDK13 cyclin dependent kinase 13 acts_upstream_of_or_within ISO (MGI:5467199|PMID:22547058) MGI PMID:22547058 MGI:5467199 NCBI chr 7:44,138,345...44,285,606
Ensembl chr 7:44,177,204...44,324,683
JBrowse link
G ESRRB estrogen related receptor beta involved_in ISO (MGI:5887187|PMID:26206133) UniProt PMID:26206133 MGI:5887187 NCBI chr14:56,868,361...57,060,552
Ensembl chr14:75,839,333...76,266,895
JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in ISO (PMID:19682396) UniProt PMID:19682396 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257
JBrowse link
G HES5 hes family bHLH transcription factor 5 involved_in ISO (PMID:19682396) UniProt PMID:19682396 NCBI chr 1:1,261,260...1,263,128 JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:21235343)
(MGI:5908336|PMID:21235343)
UniProt PMID:21235343 MGI:5908336 NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031
JBrowse link
G JAG1 jagged canonical Notch ligand 1 involved_in ISO (PMID:19682396) UniProt PMID:19682396 NCBI chr20:10,582,234...10,618,507
Ensembl chr20:10,582,094...10,618,383
JBrowse link
G LBH LBH regulator of WNT signaling pathway involved_in ISO (MGI:5634223|PMID:25655704) CAFA PMID:25655704 MGI:5634223 NCBI chr2A:30,244,474...30,273,048
Ensembl chr2A:30,320,249...30,411,779
JBrowse link
G LOC100993446 histone H1.8 involved_in ISO (MGI:5559660|PMID:22868987) UniProt PMID:22868987 MGI:5559660 NCBI chr 3:126,600,616...126,609,319
Ensembl chr 3:133,952,981...133,961,243
JBrowse link
G NCOA3 nuclear receptor coactivator 3 acts_upstream_of_or_within ISO (MGI:5467164|PMID:22977234) MGI PMID:22977234 MGI:5467164 NCBI chr20:43,838,227...43,992,407
Ensembl chr20:45,000,422...45,073,549
JBrowse link
G NELFB negative elongation factor complex member B involved_in ISO (MGI:3845453|PMID:19340312) UniProt PMID:19340312 MGI:3845453 NCBI chr 9:108,314,535...108,333,050
Ensembl chr 9:137,278,964...137,301,751
JBrowse link
G NOTCH1 notch receptor 1 involved_in ISO (PMID:19682396) UniProt PMID:19682396 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740
JBrowse link
G STAT3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (MGI:5659778|PMID:25335925) MGI PMID:25335925 MGI:5659778 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G TRIM6 tripartite motif containing 6 involved_in ISO (MGI:5492022|PMID:22328504) UniProt PMID:22328504 MGI:5492022 NCBI chr11:5,731,256...5,748,057
Ensembl chr11:5,413,491...5,460,532
JBrowse link
G YAP1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO (MGI:4455217|PMID:20516196) MGI PMID:20516196 MGI:4455217 NCBI chr11:97,061,367...97,186,961
Ensembl chr11:100,552,424...100,681,301
JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 involved_in ISO (PMID:32169943) UniProt PMID:32169943 NCBI chr 1:28,007,592...28,041,179
Ensembl chr 1:29,038,831...29,070,533
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in ISO (MGI:5500826|PMID:23748442) UniProt PMID:23748442 MGI:5500826 NCBI chr2A:43,311,744...43,315,928 JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHX36 DEAH-box helicase 36 involved_in ISO (MGI:6201954|PMID:26489465) UniProt PMID:26489465 MGI:6201954 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G GATA4 GATA binding protein 4 acts_upstream_of_or_within ISO (PMID:16137232) BHF-UCL PMID:16137232 NCBI chr 8:7,442,921...7,526,731 JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (PMID:16137232) BHF-UCL PMID:16137232 NCBI chr18:15,411,764...15,444,402 JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in ISO (MGI:3784761|PMID:11889119) BHF-UCL PMID:11889119 MGI:3784761 NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514
JBrowse link
G TBX5 T-box transcription factor 5 involved_in ISO (PMID:11431700) UniProt PMID:11431700 NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739
JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in ISO (PMID:15896309) UniProt PMID:15896309 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041
JBrowse link
positive regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXC1 forkhead box C1 involved_in ISO (MGI:5569870|PMID:24590069) UniProt PMID:24590069 MGI:5569870 NCBI chr 6:1,429,051...1,433,180 JBrowse link
positive regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in ISO (PMID:18672106) UniProt PMID:18672106 NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
JBrowse link
G SOX5 SRY-box transcription factor 5 involved_in ISO (PMID:21401405) UniProt PMID:21401405 NCBI chr12:62,361,631...62,780,805
Ensembl chr12:64,971,818...65,388,694
JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in ISO (PMID:21401405) UniProt PMID:21401405 NCBI chr11:16,053,730...16,488,566
Ensembl chr11:15,747,495...16,175,246
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISO (PMID:21401405) UniProt PMID:21401405 NCBI chr17:66,028,737...66,034,122 JBrowse link
positive regulation of stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta acts_upstream_of_or_within ISO (MGI:5319061|PMID:22064483) MGI PMID:22064483 MGI:5319061 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771
JBrowse link
G HOXB4 homeobox B4 involved_in ISO (PMID:18932205) BHF-UCL PMID:18932205 NCBI chr17:8,958,253...8,961,261
Ensembl chr17:9,143,173...9,146,161
JBrowse link
G NUDT21 nudix hydrolase 21 involved_in ISO (MGI:6110185|PMID:29249356) UniProt PMID:29249356 MGI:6110185 NCBI chr16:36,715,373...36,737,593
Ensembl chr16:55,851,302...55,869,856
JBrowse link
G PTN pleiotrophin involved_in ISO (MGI:3045656|PMID:15121180) UniProt PMID:15121180 MGI:3045656 NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
JBrowse link
G PWP1 PWP1 homolog, endonuclein acts_upstream_of_or_within ISO (MGI:5659778|PMID:25335925) MGI PMID:25335925 MGI:5659778 NCBI chr12:105,255,755...105,282,519
Ensembl chr12:108,652,024...108,679,503
JBrowse link
G RBM24 RNA binding motif protein 24 involved_in ISO (PMID:26990106) UniProt PMID:26990106 NCBI chr 6:17,140,450...17,153,035 JBrowse link
G SP7 Sp7 transcription factor involved_in ISO (PMID:18932205) BHF-UCL PMID:18932205 NCBI chr12:35,409,055...35,427,871
Ensembl chr12:36,199,673...36,209,494
JBrowse link
G TACSTD2 tumor associated calcium signal transducer 2 acts_upstream_of_or_within ISO (MGI:5440097|PMID:23070813) MGI PMID:23070813 MGI:5440097 NCBI chr 1:57,838,661...57,841,444
Ensembl chr 1:59,545,625...59,546,596
JBrowse link
G TCF15 transcription factor 15 involved_in ISO (MGI:6508503|PMID:23395635) UniProt PMID:23395635 MGI:6508503 NCBI chr20:811,907...817,971 JBrowse link
G VSIR V-set immunoregulatory receptor acts_upstream_of_or_within ISO (MGI:5465045|PMID:22751012) MGI PMID:22751012 MGI:5465045 NCBI chr10:68,218,230...68,243,687
Ensembl chr10:70,742,062...70,767,613
JBrowse link
regulation of hematopoietic stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK6 cyclin dependent kinase 6 acts_upstream_of_or_within ISO (MGI:5636128|PMID:25342715) MGI PMID:25342715 MGI:5636128 NCBI chr 7:84,603,419...84,835,082 JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in ISO (MGI:5487705|PMID:23403623) UniProt PMID:23403623 MGI:5487705 NCBI chr2A:37,130,386...37,184,587
Ensembl chr2A:37,895,814...37,941,686
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in ISO (MGI:6414739|PMID:32103174) UniProt PMID:32103174 MGI:6414739 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
G PUS7 pseudouridine synthase 7 involved_in ISO (PMID:29628141) UniProt PMID:29628141 NCBI chr 7:97,447,332...97,512,812
Ensembl chr 7:110,177,284...110,243,923
JBrowse link
G SETD1A SET domain containing 1A, histone lysine methyltransferase involved_in ISO (PMID:27141965) ParkinsonsUK-UCL PMID:27141965 NCBI chr16:23,984,260...24,019,579 JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein 2 involved_in ISO (MGI:6316688|PMID:30065315), (MGI:6317061|PMID:30150673) UniProt PMID:30065315 PMID:30150673 MGI:6316688 MGI:6317061 NCBI chr 1:28,007,592...28,041,179
Ensembl chr 1:29,038,831...29,070,533
JBrowse link
regulation of mesenchymal stem cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRA platelet derived growth factor receptor alpha involved_in ISO (PMID:21596750) UniProt PMID:21596750 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097
JBrowse link
G SLC4A11 solute carrier family 4 member 11 involved_in ISO (MGI:6695689|PMID:33247189) UniProt PMID:33247189 MGI:6695689 NCBI chr20:3,311,640...3,324,966
Ensembl chr20:3,074,804...3,086,157
JBrowse link
regulation of neural crest cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912
JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A NOT|involved_in ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12656
    developmental process 5904
      regulation of developmental process 2429
        regulation of cell differentiation 1562
          regulation of stem cell differentiation 61
            negative regulation of stem cell differentiation + 25
            positive regulation of stem cell differentiation + 21
            regulation of cardioblast differentiation + 8
            regulation of hematopoietic stem cell differentiation + 11
            regulation of mesenchymal stem cell differentiation + 7
            regulation of neural crest cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 12656
    cellular process 11789
      cellular developmental process 3832
        cell differentiation 3766
          regulation of cell differentiation 1562
            regulation of stem cell differentiation 61
              negative regulation of stem cell differentiation + 25
              positive regulation of stem cell differentiation + 21
              regulation of cardioblast differentiation + 8
              regulation of hematopoietic stem cell differentiation + 11
              regulation of mesenchymal stem cell differentiation + 7
              regulation of neural crest cell differentiation + 1
paths to the root