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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cardiac muscle cell differentiation
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Accession:GO:2000725 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation.
Synonyms:exact_synonym: regulation of cardiomyocyte differentiation
 related_synonym: regulation of heart muscle cell differentiation


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negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:18545679) BHF-UCL PMID:18545679 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chrNW_004936787:307,290...309,963 JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5902683|PMID:18371447) BHF-UCL PMID:18371447 MGI:5902683 NCBI chrNW_004937098:212,704...220,589 JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 involved_in ISO (PMID:23939491) BHF-UCL PMID:23939491 NCBI chrNW_004936545:7,286,018...7,407,623 JBrowse link
G Fzd7 frizzled class receptor 7 involved_in ISO (PMID:23939491) BHF-UCL PMID:23939491 NCBI chrNW_004936726:1,256,684...1,275,324 JBrowse link
G Hdac3 histone deacetylase 3 acts_upstream_of_or_within ISO (MGI:5571645|PMID:24565863) MGI PMID:24565863 MGI:5571645 NCBI chrNW_004936504:12,530,546...12,546,556 JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO (PMID:20081117) BHF-UCL PMID:20081117 NCBI chrNW_004936528:2,331,706...2,912,423 JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in ISO (MGI:3689643|PMID:16151019) BHF-UCL PMID:16151019 MGI:3689643 NCBI chrNW_004936497:12,242,869...12,278,012 JBrowse link
positive regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 involved_in ISO (MGI:5784966|PMID:24974728) BHF-UCL PMID:24974728 MGI:5784966 NCBI chrNW_004936677:3,173,054...3,181,475 JBrowse link
G Efnb2 ephrin B2 involved_in ISO (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chrNW_004936472:5,138,751...5,181,630 JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (MGI:5315691|PMID:18545679) BHF-UCL PMID:18545679 MGI:5315691 NCBI chrNW_004936673:1,394,743...1,399,726 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (MGI:5784966|PMID:24974728) BHF-UCL PMID:24974728 MGI:5784966 NCBI chrNW_004936536:6,730,070...6,893,818 JBrowse link
G Kat2a lysine acetyltransferase 2A ISO RGD PMID:20835911 RGD:8693751 NCBI chrNW_004936490:16,952,698...16,960,424 JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (PMID:9857019)
(MGI:3830899|PMID:16680724)
UniProt PMID:9857019 PMID:16680724 MGI:3830899 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Myocd myocardin involved_in ISO (PMID:18451334) BHF-UCL PMID:18451334 NCBI chrNW_004936595:5,256,615...5,356,563 JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (PMID:25163461) BHF-UCL PMID:25163461 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chrNW_004936864:150,742...179,205 JBrowse link
positive regulation of cardiac muscle fiber development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:20702560) BHF-UCL PMID:20702560 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12164
    developmental process 5729
      regulation of developmental process 2368
        regulation of cell differentiation 1526
          regulation of cardiocyte differentiation 31
            regulation of cardiac muscle cell differentiation 19
              negative regulation of cardiac muscle cell differentiation + 8
              positive regulation of cardiac muscle cell differentiation + 11
              regulation of cardiac muscle fiber development + 1
Path 2
Term Annotations click to browse term
  biological_process 12164
    developmental process 5729
      anatomical structure development 5357
        multicellular organism development 4905
          system development 4621
            circulatory system development 1117
              heart development 639
                cardiac muscle tissue development 244
                  cardiac muscle cell differentiation 142
                    regulation of cardiac muscle cell differentiation 19
                      negative regulation of cardiac muscle cell differentiation + 8
                      positive regulation of cardiac muscle cell differentiation + 11
                      regulation of cardiac muscle fiber development + 1
paths to the root