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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of sodium ion transmembrane transporter activity
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Accession:GO:2000649 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.
Synonyms:exact_synonym: regulation of sodium transporter activity


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regulation of sodium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO (PMID:17060380), (PMID:17275750) RGD PMID:17060380 PMID:17275750 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Fgf12 fibroblast growth factor 12 involved_in IDA PMID:12401812 BHF-UCL PMID:12401812 RGD:6484231 NCBI chr11:75,606,360...76,171,078
Ensembl chr11:75,905,443...76,168,989
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 involved_in IEA
ISO
IBA
GO_REF:0000107
(MGI:3575337|PMID:15563542), (MGI:5582172|PMID:17095720)
PMID:21873635
Ensembl
RGD
PMID:15563542 PMID:17095720, PMID:21873635 GO_REF:0000107 MGI:3575337 MGI:5582172, RGD:13792537 NCBI chr 1:89,484,197...89,488,279
Ensembl chr 1:89,484,199...89,488,223
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3586329 (MGI:3584231|PMID:15755730)
RGD PMID:15755730, PMID:21873635 MGI:3584231, RGD:13792537 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:89,502,561...89,510,146
Ensembl chr 1:89,502,562...89,509,343
JBrowse link
G Fxyd4 FXYD domain-containing ion transport regulator 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:149,984,206...149,988,744
Ensembl chr 4:149,984,206...149,988,295
JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:89,464,853...89,474,450
Ensembl chr 1:89,464,860...89,474,252
JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:49,676,520...49,703,419
Ensembl chr 8:49,676,540...49,703,419
JBrowse link
G Fxyd7 FXYD domain-containing ion transport regulator 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:89,474,601...89,484,069
Ensembl chr 1:89,474,601...89,483,988
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like involved_in ISO (PMID:17967977), (PMID:19666841) RGD PMID:17967977 PMID:19666841 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 involved_in ISO (PMID:16930557) RGD PMID:16930557 NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186
JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:18184654), (PMID:21621375), (PMID:23420830)
(MGI:5508678|PMID:23420830)
RGD PMID:18184654 PMID:21621375 PMID:23420830 MGI:5508678 NCBI chr10:55,559,049...55,560,420
Ensembl chr10:55,559,041...55,560,422
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IEA
IBA
(PMID:19808477)
GO_REF:0000002
PMID:21873635
RGD
InterPro
PMID:19808477, PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in ISO
IBA
(PMID:19808477)
PMID:21873635
RGD PMID:19808477, PMID:21873635 RGD:13792537 NCBI chr 8:49,419,003...49,431,110
Ensembl chr 8:49,418,965...49,427,689
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO
IBA
(PMID:20042427)
PMID:21873635
RGD PMID:20042427, PMID:21873635 RGD:13792537 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17592081), (PMID:24297919)
UniProt
RGD
PMID:17592081 PMID:24297919, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:49,441,106...49,456,279
Ensembl chr 8:49,441,106...49,456,279
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:16728661)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:16728661 GO_REF:0000024 GO_REF:0000107 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link
negative regulation of acid-sensing ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stoml1 stomatin like 1 acts_upstream_of_or_within ISO (MGI:5619720|PMID:24247984) RGD PMID:24247984 MGI:5619720 NCBI chr 8:63,037,135...63,045,024
Ensembl chr 8:63,036,976...63,045,030
JBrowse link
negative regulation of calcium:sodium antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 involved_in IMP PMID:17442282 BHF-UCL PMID:17442282 RGD:6903343 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
negative regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrn agrin involved_in ISO (MGI:4352602|PMID:19376779) RGD PMID:19376779 MGI:4352602 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 IMP RGD PMID:15280368 RGD:1598989 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
negative regulation of sodium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in ISO (PMID:22514276) RGD PMID:22514276 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Hecw1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:53,229,997...53,777,474
Ensembl chr17:53,229,785...53,773,657
JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:60,451,476...60,843,160
Ensembl chr 9:60,457,215...60,672,246
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:10642508)
Ensembl
RGD
PMID:10642508, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in IBA
ISO
PMID:21873635
(PMID:15217910)
RGD PMID:15217910, PMID:21873635 RGD:13792537 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISO (PMID:25531585) RGD PMID:25531585 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22493497) RGD PMID:22493497 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (PMID:25531585) RGD PMID:25531585 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414
JBrowse link
negative regulation of sodium:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd3 dopamine receptor D3 IMP RGD PMID:15265811 RGD:1625070 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 acts_upstream_of_or_within ISO MGI:2386785 (MGI:3702223|PMID:12586353) RGD PMID:12586353 MGI:3702223 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
positive regulation of calcium:sodium antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 involved_in ISO (MGI:4359299|PMID:19683723) RGD PMID:19683723 MGI:4359299 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISO (PMID:15105296) RGD PMID:15105296 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
positive regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 involved_in ISO UniProtKB:P50993|UniProtKB:Q13733 (PMID:10636900), (PMID:18728015), (PMID:19542013), (PMID:20100892), (PMID:23954377)
(MGI:4359299|PMID:19683723)
UniProtKB:P05023 (PMID:18052210), (PMID:18075585), (PMID:19542013)
RGD PMID:10636900 PMID:18052210 PMID:18075585 PMID:18728015 PMID:19542013 PMID:19683723 PMID:20100892 PMID:23954377 MGI:4359299 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:12205083 RGD:727418 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:22492652) RGD PMID:22492652 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
positive regulation of sodium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 involved_in IMP PMID:18180363 BHF-UCL PMID:18180363 RGD:6767295 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Cnksr3 Cnksr family member 3 acts_upstream_of_or_within ISO (MGI:5467171|PMID:22851176) RGD PMID:22851176 MGI:5467171 NCBI chr 1:43,789,797...43,884,267
Ensembl chr 1:43,789,791...43,884,267
JBrowse link
G Dmd dystrophin involved_in ISO (MGI:5487517|PMID:21677768) RGD PMID:21677768 MGI:5487517 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Glrx glutaredoxin involved_in ISO (PMID:19542013) RGD PMID:19542013 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:152,452,211...152,578,469
Ensembl chr 4:152,452,848...152,578,446
JBrowse link
G Wnk2 WNK lysine deficient protein kinase 2 involved_in IBA
ISO
PMID:21873635
(PMID:21733846)
RGD PMID:21733846, PMID:21873635 RGD:13792537 NCBI chr17:15,923,508...16,032,271
Ensembl chr17:15,924,048...16,032,420
JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in IBA
ISO
PMID:21873635
(PMID:16275913), (PMID:21613606)
RGD PMID:16275913 PMID:21613606, PMID:21873635 RGD:13792537 NCBI chr  X:20,316,081...20,459,245
Ensembl chr  X:20,316,893...20,454,357
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:89,181,139...89,198,213
Ensembl chr10:89,181,165...89,198,213
JBrowse link
positive regulation of sodium:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:11350981), (PMID:8901634)
UniProt
RGD
PMID:8901634 PMID:11350981 GO_REF:0000024 NCBI chr 3:111,354,506...111,389,998
Ensembl chr 3:111,354,506...111,389,989
JBrowse link
G Drd4 dopamine receptor D4 involved_in ISO
IEA
(PMID:7512953)
GO_REF:0000107
RGD
Ensembl
PMID:7512953 GO_REF:0000107 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Tesc tescalcin involved_in ISO (PMID:18321853) RGD PMID:18321853 NCBI chr12:44,141,258...44,174,701
Ensembl chr12:44,141,422...44,174,583
JBrowse link
positive regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:24097558 RGD:39939085 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Kif5b kinesin family member 5B IMP RGD PMID:24198377 RGD:11073607 NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096
JBrowse link
regulation of acid-sensing ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stom stomatin involved_in ISO (MGI:5441174|PMID:22850675) RGD PMID:22850675 MGI:5441174 NCBI chr 3:14,515,576...14,538,199
Ensembl chr 3:14,514,868...14,538,241
JBrowse link
regulation of kainate selective glutamate receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klhl24 kelch-like family member 24 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr11:84,613,101...84,643,674
Ensembl chr11:84,615,760...84,633,504
JBrowse link
G Neto1 neuropilin and tolloid like 1 involved_in ISO (PMID:26277340) RGD PMID:26277340 NCBI chr18:83,471,342...83,585,043
Ensembl chr18:83,471,342...83,584,357
JBrowse link
G Neto2 neuropilin and tolloid like 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:22,450,579...22,486,530
Ensembl chr19:22,450,030...22,486,531
JBrowse link
regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxyd1 FXYD domain-containing ion transport regulator 1 involved_in ISO (PMID:12169672) RGD PMID:12169672 NCBI chr 1:89,484,197...89,488,279
Ensembl chr 1:89,484,199...89,488,223
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 IDA RGD PMID:11756431 RGD:625472 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf11 fibroblast growth factor 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:56,403,320...56,410,816
Ensembl chr10:56,403,256...56,409,017
JBrowse link
G Fgf12 fibroblast growth factor 12 involved_in IBA
ISO
ISS
PMID:21873635
(PMID:27164707)
GO_REF:0000024
RGD
UniProt
PMID:27164707, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:75,606,360...76,171,078
Ensembl chr11:75,905,443...76,168,989
JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Fgf14 fibroblast growth factor 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:110,382,274...111,077,027
Ensembl chr15:110,385,217...110,612,681
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(MGI:5575449|PMID:23542581)
GO_REF:0000107
RGD
Ensembl
PMID:23542581 GO_REF:0000107 MGI:5575449 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in IDA PMID:28012039 UniProt PMID:28012039 RGD:13825439 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Slmap sarcolemma associated protein involved_in ISO
IBA
(PMID:23064965)
PMID:21873635
RGD PMID:23064965, PMID:21873635 RGD:13792537 NCBI chr16:2,112,271...2,227,336
Ensembl chr16:2,112,274...2,227,309
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of molecular function 3070
        regulation of transporter activity 303
          regulation of transmembrane transporter activity 289
            regulation of ion transmembrane transporter activity 278
              regulation of sodium ion transmembrane transporter activity 56
                negative regulation of sodium ion transmembrane transporter activity + 14
                positive regulation of sodium ion transmembrane transporter activity + 17
                regulation of P-type sodium:potassium-exchanging transporter activity + 6
                regulation of acid-sensing ion channel activity + 2
                regulation of calcium:sodium antiporter activity + 3
                regulation of kainate selective glutamate receptor activity 3
                regulation of sodium:proton antiporter activity + 5
                regulation of voltage-gated sodium channel activity + 9
Path 2
Term Annotations click to browse term
  biological_process 19491
    localization 6443
      establishment of localization 4862
        transport 4698
          ion transport 1637
            cation transport 1258
              metal ion transport 940
                sodium ion transport 246
                  regulation of sodium ion transport 96
                    regulation of sodium ion transmembrane transport 65
                      regulation of sodium ion transmembrane transporter activity 56
                        negative regulation of sodium ion transmembrane transporter activity + 14
                        positive regulation of sodium ion transmembrane transporter activity + 17
                        regulation of P-type sodium:potassium-exchanging transporter activity + 6
                        regulation of acid-sensing ion channel activity + 2
                        regulation of calcium:sodium antiporter activity + 3
                        regulation of kainate selective glutamate receptor activity 3
                        regulation of sodium:proton antiporter activity + 5
                        regulation of voltage-gated sodium channel activity + 9
paths to the root