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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of sodium ion transmembrane transporter activity
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Accession:GO:2000649 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.
Synonyms:exact_synonym: regulation of sodium transporter activity


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regulation of sodium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV3 caveolin 3 involved_in IDA (PMID:17060380), (PMID:17275750) BHF-UCL PMID:17060380 PMID:17275750 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
JBrowse link
G FGF12 fibroblast growth factor 12 involved_in ISS (PMID:12401812) BHF-UCL PMID:12401812 NCBI chr 3:192,139,390...192,727,541
Ensembl chr 3:192,139,390...192,767,764
JBrowse link
G FXYD1 FXYD domain containing ion transport regulator 1 involved_in ISS
IBA
(PMID:21873635) BHF-UCL
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr19:35,137,206...35,143,109
Ensembl chr19:35,138,824...35,143,109
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3584231|PMID:15755730)
GO_Central
MGI
PMID:15755730 PMID:21873635 MGI:3584231 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
JBrowse link
G FXYD3 FXYD domain containing ion transport regulator 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:35,115,823...35,124,324
Ensembl chr19:35,115,823...35,124,324
JBrowse link
G FXYD4 FXYD domain containing ion transport regulator 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:43,371,636...43,376,335
Ensembl chr10:43,371,636...43,376,335
JBrowse link
G FXYD5 FXYD domain containing ion transport regulator 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:35,154,735...35,169,881
Ensembl chr19:35,154,730...35,169,881
JBrowse link
G FXYD6 FXYD domain containing ion transport regulator 6 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:117,836,981...117,877,430
Ensembl chr11:117,836,976...117,877,486
JBrowse link
G FXYD6P3 FXYD domain containing ion transport regulator 6 pseudogene 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:73,875,509...73,876,960
Ensembl chr  X:73,875,068...73,875,635
JBrowse link
G FXYD7 FXYD domain containing ion transport regulator 7 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:35,143,255...35,154,302
Ensembl chr19:35,143,250...35,154,302
JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like involved_in IMP (PMID:17967977), (PMID:19666841) BHF-UCL PMID:17967977 PMID:19666841 NCBI chr 3:32,106,620...32,168,715
Ensembl chr 3:32,105,689...32,168,709
JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 involved_in IDA (PMID:16930557) BHF-UCL PMID:16930557 NCBI chr 9:109,375,694...109,538,395
Ensembl chr 9:109,375,466...109,498,313
JBrowse link
G RANGRF RAN guanine nucleotide release factor involved_in IMP
IDA
(PMID:21621375), (PMID:23420830)
(PMID:18184654)
BHF-UCL PMID:18184654 PMID:21621375 PMID:23420830 NCBI chr17:8,288,670...8,290,087
Ensembl chr17:8,288,654...8,290,092
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IDA
IEA
IBA
(PMID:19808477)
(PMID:21873635)
BHF-UCL
InterPro
GO_Central
PMID:19808477 PMID:21873635 GO_REF:0000002 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IDA
IBA
(PMID:19808477)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:19808477 PMID:21873635 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IBA
IMP
(PMID:21873635)
(PMID:20042427)
GO_Central
BHF-UCL
PMID:20042427 PMID:21873635 NCBI chr11:123,629,187...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IDA
IBA
(PMID:17592081), (PMID:24297919)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:17592081 PMID:21873635 PMID:24297919 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888
JBrowse link
G UTRN utrophin involved_in ISS (PMID:21677768) BHF-UCL PMID:21677768 NCBI chr 6:144,285,261...144,853,034
Ensembl chr 6:144,285,701...144,853,034
JBrowse link
G YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta involved_in IDA (PMID:16728661) BHF-UCL PMID:16728661 NCBI chr22:31,944,535...31,957,603
Ensembl chr22:31,944,522...31,957,603
JBrowse link
negative regulation of acid-sensing ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STOML1 stomatin like 1 acts_upstream_of_or_within ISO (MGI:5619720|PMID:24247984) MGI PMID:24247984 MGI:5619720 NCBI chr15:73,978,926...73,994,636
Ensembl chr15:73,978,926...73,994,622
JBrowse link
negative regulation of calcium:sodium antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
negative regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGRN agrin involved_in ISO (MGI:4352602|PMID:19376779) BHF-UCL PMID:19376779 MGI:4352602 NCBI chr 1:1,020,102...1,056,119
Ensembl chr 1:1,020,120...1,056,118
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO RGD PMID:15280368 RGD:1598989 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
JBrowse link
negative regulation of sodium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in TAS (PMID:19193863) BHF-UCL PMID:19193863 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in IDA (PMID:22514276) BHF-UCL PMID:22514276 NCBI chr 4:113,451,032...113,762,177
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:43,112,580...43,566,001
Ensembl chr 7:43,112,629...43,566,001
JBrowse link
G HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:196,194,072...196,593,692
Ensembl chr 2:196,189,099...196,593,684
JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase involved_in IDA
IBA
(PMID:10642508)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:10642508 PMID:21873635 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660
JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase involved_in IBA
IDA
(PMID:21873635)
(PMID:15217910)
GO_Central
BHF-UCL
PMID:15217910 PMID:21873635 NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IDA (PMID:25531585) ParkinsonsUK-UCL PMID:25531585 NCBI chr 2:19,351,485...19,358,623
Ensembl chr 2:19,351,485...19,358,623
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IDA (PMID:22493497) BHF-UCL PMID:22493497 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link
G PRKCE protein kinase C epsilon involved_in TAS (PMID:19193863) BHF-UCL PMID:19193863 NCBI chr 2:45,651,315...46,187,990
Ensembl chr 2:45,651,345...46,187,990
JBrowse link
G STK39 serine/threonine kinase 39 involved_in IDA (PMID:25531585) ParkinsonsUK-UCL PMID:25531585 NCBI chr 2:167,954,020...168,247,595
Ensembl chr 2:167,954,020...168,247,595
JBrowse link
negative regulation of sodium:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD3 dopamine receptor D3 involved_in IEA
ISO
Ensembl
RGD
PMID:15265811 GO_REF:0000107 RGD:1625070 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G SLC9A3R1 SLC9A3 regulator 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3702223|PMID:12586353) Ensembl
MGI
PMID:12586353 GO_REF:0000107 MGI:3702223 NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353
JBrowse link
positive regulation of calcium:sodium antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,132,722
JBrowse link
G SLC9A1 solute carrier family 9 member A1 involved_in IMP (PMID:15105296) BHF-UCL PMID:15105296 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
JBrowse link
positive regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 involved_in IDA
IGI
ISS
(PMID:10636900), (PMID:19542013), (PMID:23954377)
(PMID:20100892)
(PMID:18728015), (PMID:20100892)
ARUK-UCL
BHF-UCL
PMID:10636900 PMID:18728015 PMID:19542013 PMID:20100892 PMID:23954377 GO_REF:0000024 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,132,722
JBrowse link
G DNM2 dynamin 2 involved_in IEA
ISO
Ensembl
RGD
PMID:12205083 GO_REF:0000107 RGD:727418 NCBI chr19:10,718,079...10,831,903
Ensembl chr19:10,718,055...10,833,488
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:22492652) AgBase PMID:22492652 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
JBrowse link
positive regulation of sodium ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK3 ankyrin 3 involved_in ISS (PMID:18180363) BHF-UCL PMID:18180363 NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490
JBrowse link
G CNKSR3 CNKSR family member 3 acts_upstream_of_or_within ISO (MGI:5467171|PMID:22851176) MGI PMID:22851176 MGI:5467171 NCBI chr 6:154,387,515...154,510,685
Ensembl chr 6:154,387,515...154,510,685
JBrowse link
G DMD dystrophin involved_in ISS
IEA
(PMID:21677768) BHF-UCL
Ensembl
PMID:21677768 GO_REF:0000107 NCBI chr  X:31,119,219...33,339,460
Ensembl chr  X:31,097,677...33,339,609
JBrowse link
G GLRX glutaredoxin involved_in IDA (PMID:19542013) BHF-UCL PMID:19542013 NCBI chr 5:95,813,849...95,822,726
Ensembl chr 5:95,751,319...95,822,726
JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:752,579...911,452
Ensembl chr12:752,579...911,452
JBrowse link
G WNK2 WNK lysine deficient protein kinase 2 involved_in IMP
IBA
(PMID:21733846)
(PMID:21873635)
UniProt
GO_Central
PMID:21733846 PMID:21873635 NCBI chr 9:93,184,139...93,327,581
Ensembl chr 9:93,184,916...93,320,572
JBrowse link
G WNK3 WNK lysine deficient protein kinase 3 involved_in IMP
IBA
IDA
(PMID:21613606)
(PMID:21873635)
(PMID:16275913)
UniProt
GO_Central
PMID:16275913 PMID:21613606 PMID:21873635 NCBI chr  X:54,192,823...54,358,695
Ensembl chr  X:54,192,823...54,358,642
JBrowse link
G WNK4 WNK lysine deficient protein kinase 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:42,779,701...42,797,066
Ensembl chr17:42,780,610...42,797,066
JBrowse link
positive regulation of sodium:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN4 actinin alpha 4 involved_in NAS (PMID:11948184) UniProt PMID:11948184 NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589
JBrowse link
G CHP1 calcineurin like EF-hand protein 1 involved_in IDA
ISS
(PMID:11350981), (PMID:8901634) UniProt PMID:8901634 PMID:11350981 GO_REF:0000024 NCBI chr15:41,231,156...41,281,887
Ensembl chr15:41,230,839...41,281,887
JBrowse link
G DRD4 dopamine receptor D4 involved_in IDA (PMID:7512953) BHF-UCL PMID:7512953 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G TESC tescalcin involved_in IDA (PMID:18321853) UniProt PMID:18321853 NCBI chr12:117,038,923...117,099,490
Ensembl chr12:117,038,923...117,099,479
JBrowse link
positive regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 ISO RGD PMID:24097558 RGD:39939085 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815
JBrowse link
G KIF5B kinesin family member 5B involved_in IEA
ISO
Ensembl
RGD
PMID:24198377 GO_REF:0000107 RGD:11073607 NCBI chr10:32,009,015...32,056,425
Ensembl chr10:32,009,015...32,056,425
JBrowse link
regulation of acid-sensing ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STOM stomatin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:121,338,987...121,370,250
Ensembl chr 9:121,338,987...121,370,304
JBrowse link
regulation of kainate selective glutamate receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KLHL24 kelch like family member 24 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:183,635,619...183,684,519
Ensembl chr 3:183,635,610...183,684,519
JBrowse link
G NETO1 neuropilin and tolloid like 1 involved_in IDA (PMID:26277340) SynGO PMID:26277340 NCBI chr18:72,742,314...72,867,987
Ensembl chr18:72,742,314...72,868,146
JBrowse link
G NETO2 neuropilin and tolloid like 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:47,077,703...47,144,025
Ensembl chr16:47,077,703...47,143,945
JBrowse link
regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXYD1 FXYD domain containing ion transport regulator 1 involved_in ISO (PMID:12169672) UniProt PMID:12169672 NCBI chr19:35,137,206...35,143,109
Ensembl chr19:35,138,824...35,143,109
JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO RGD PMID:11756431 RGD:625472 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698
JBrowse link
regulation of sodium:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC9A3R1 SLC9A3 regulator 1 involved_in NAS (PMID:9560162) UniProt PMID:9560162 NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353
JBrowse link
regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF11 fibroblast growth factor 11 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:7,438,298...7,444,937
Ensembl chr17:7,438,273...7,444,937
JBrowse link
G FGF12 fibroblast growth factor 12 involved_in IMP
IBA
(PMID:27164707)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635 PMID:27164707 NCBI chr 3:192,139,390...192,727,541
Ensembl chr 3:192,139,390...192,767,764
JBrowse link
G FGF13 fibroblast growth factor 13 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:138,614,727...139,222,889
Ensembl chr  X:138,614,727...139,222,777
JBrowse link
G FGF14 fibroblast growth factor 14 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:101,710,804...102,402,443
Ensembl chr13:101,710,804...102,402,457
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SLMAP sarcolemma associated protein involved_in IMP
IBA
(PMID:23064965)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:21873635 PMID:23064965 NCBI chr 3:57,756,229...57,930,013
Ensembl chr 3:57,755,450...57,930,003
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18536
    biological regulation 13081
      regulation of molecular function 3271
        regulation of transporter activity 325
          regulation of transmembrane transporter activity 306
            regulation of ion transmembrane transporter activity 295
              regulation of sodium ion transmembrane transporter activity 61
                negative regulation of sodium ion transmembrane transporter activity + 16
                positive regulation of sodium ion transmembrane transporter activity + 19
                regulation of P-type sodium:potassium-exchanging transporter activity + 6
                regulation of acid-sensing ion channel activity + 2
                regulation of calcium:sodium antiporter activity + 3
                regulation of kainate selective glutamate receptor activity 3
                regulation of sodium:proton antiporter activity + 6
                regulation of voltage-gated sodium channel activity + 9
Path 2
Term Annotations click to browse term
  biological_process 18536
    localization 6636
      establishment of localization 5029
        transport 4867
          ion transport 1695
            cation transport 1292
              metal ion transport 964
                sodium ion transport 260
                  regulation of sodium ion transport 104
                    regulation of sodium ion transmembrane transport 72
                      regulation of sodium ion transmembrane transporter activity 61
                        negative regulation of sodium ion transmembrane transporter activity + 16
                        positive regulation of sodium ion transmembrane transporter activity + 19
                        regulation of P-type sodium:potassium-exchanging transporter activity + 6
                        regulation of acid-sensing ion channel activity + 2
                        regulation of calcium:sodium antiporter activity + 3
                        regulation of kainate selective glutamate receptor activity 3
                        regulation of sodium:proton antiporter activity + 6
                        regulation of voltage-gated sodium channel activity + 9
paths to the root